Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Ruzhu Chen"'
Publikováno v:
European Journal of Pharmacology. 713:58-67
Secalonic acid A (SAA) is a natural compound found in marine fungi. We have reported that SAA can attenuate the cytotoxicity of colchicine in rat cortical neurons. Whether SAA can also inhibit the neurotoxicity of 1-methyl-4-phenylpyridinium (MPP + )
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b394b3eb53c64b290613f92de05f244
https://doi.org/10.1016/j.ejphar.2013.04.029
https://doi.org/10.1016/j.ejphar.2013.04.029
Publikováno v:
Journal of Pharmacy and Pharmacology. 63:1169-1174
Objectives Previously, the flavonoid (±)-catechin was shown to exert potent neuroprotective action in the mouse 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinson's disease model. The purpose of this study was to investigate whether the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b45412b660c4e7687dea70966d9e590b
https://doi.org/10.1111/j.2042-7158.2011.01293.x
https://doi.org/10.1111/j.2042-7158.2011.01293.x
Publikováno v:
Neurochemistry International. 58:85-91
There are few articles about the cytotoxicity evoked by secalonic acid A (SAA) in some tumor cells. It has not yet been reported whether SAA has any action on neurons of the central nervous system. The aim of this study was to investigate the protect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d67dd35b1e1a942faceeefaf3158cb0
https://doi.org/10.1016/j.neuint.2010.10.016
https://doi.org/10.1016/j.neuint.2010.10.016
Autor:
Dan Li, Ruzhu Chen, Mingtao Li, Wenming Li, Bin Song, Yick-Pang Ching, Yulin Liu, Chi Ma, Bingquan Lai, Chunyi Ying, Zhongmin Yuan
Publikováno v:
Journal of Biological Chemistry. 282:30901-30909
In cerebellar granule neurons, a BH3-only Bcl-2 family member, death protein 5/harakiri, is up-regulated in a JNK-dependent manner during apoptosis induced by potassium deprivation. However, it is not clear whether c-Jun is directly involved in the i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c370fb3dc7ac833562bbccce68b0574
https://doi.org/10.1074/jbc.m608694200
https://doi.org/10.1074/jbc.m608694200
Autor:
Yi Yang, Wenming Li, Ruzhu Chen, Yizheng Wang, Hao-Lan Ruan, Yifan Han, Yan You, Xiaonan Zhu, Wenya Wang, Chunyi Ying, Mingtao Li
Publikováno v:
Neuropharmacology. 52:1678-1684
Glycogen synthase kinase-3 beta (GSK-3 beta) is closely involved in neuronal apoptosis and pathogenesis of many neurodegenerative diseases, such as Alzheimer's disease. However, whether GSK-3 beta mediates apoptosis of dopaminergic neurons in Parkins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::def9cd5670f7884c10e3443e20a7dfed
https://doi.org/10.1016/j.neuropharm.2007.03.017
https://doi.org/10.1016/j.neuropharm.2007.03.017
Publikováno v:
Neurochemical research. 41(4)
Different patterns of olfactory dysfunction have been found in both patients and mouse models of Alzheimer's Disease. However, the underlying mechanism of the dysfunction remained unknown. Deficits of nitric oxide production in brain can cause olfact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7feead8464aee1b101395ab55035859e
https://pubmed.ncbi.nlm.nih.gov/26493872
https://pubmed.ncbi.nlm.nih.gov/26493872
Autor:
Shoufang Gong, Zhongmin Yuan, Yifan Han, Yanling Liu, Leyu Shi, Ruzhu Chen, Rongbiao Pi, Mingtao Li, Shoujian Huang, Zixu Mao, Chi Ma, Wenming Li, Chuanfu Wang
Publikováno v:
Neuroscience Letters. 375:7-12
Bcl-2-interacting mediator of cell death (Bim), a proapoptotic BH3-only protein, plays a critical role in neuronal apoptosis. Cerebellar granule neurons (CGNs) depend on activity for their survival and undergo apoptosis when deprived of depolarizing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab5b97fdeff5a2dbd483bd430ad097bc
https://doi.org/10.1016/j.neulet.2004.10.082
https://doi.org/10.1016/j.neulet.2004.10.082
Autor:
Mingtao Li, Yuanbin Xie, Zhongmin Yuan, Xuelan Wang, Zhenyu Zhu, Yanling Liu, Shoujian Huang, Wenya Wang, Hengxin Yuan, Guoquan Gao, Xiaonan Zhu, Ruzhu Chen, Zixu Mao, Xian-Guo Liu, Xuemin Wang, Chi Ma
Publikováno v:
Neuroscience Letters. 367:355-359
Previous studies have demonstrated that c-Jun NH2-terminal protein kinase (JNK) plays a crucial role in neuronal apoptosis. Here, we report that indirubin-3'-oxime, a known effective inhibitor of cyclin-dependent kinases (CDKs) and glycogen synthase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4d7ed00792a9967b8edf0b6f2489b9f
https://doi.org/10.1016/j.neulet.2004.06.044
https://doi.org/10.1016/j.neulet.2004.06.044
Autor:
Xingwen Su, Mingtao Li, Ruzhu Chen, Wengming Li, Zixu Mao, Yuanbin Xie, Wenya Wang, Zhenyu Zhu, Chi Ma, Yifan Han, Leyu Shi, Shoujian Huang
Publikováno v:
Neuroscience Research. 48:195-202
Increasing evidence suggests that c-Jun N-terminal kinase (JNK) is an important kinase mediating neuronal apoptosis in Parkinson's disease (PD) model induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). In order to study roles of JNK activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65a4c0e80b0ad6465d39c29a9b373746
https://doi.org/10.1016/j.neures.2003.10.012
https://doi.org/10.1016/j.neures.2003.10.012
Publikováno v:
The International journal of neuroscience. 122(6)
Although nicotine is known to protect against β-amyloid (Aβ)-induced neurotoxicity, the effect of nicotine on colchicine-induced neurotoxicity remains unknown. Colchicine is a microtubule-interfering agent and is able to induce neural apoptosis. He
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ae168b0f7e95d0e8ea503cebe49be46
https://pubmed.ncbi.nlm.nih.gov/22248034
https://pubmed.ncbi.nlm.nih.gov/22248034