Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Ruyuan Zhou"'
Autor:
Ruyuan Zhou, Qirou Wu, Mengqiu Wang, Seema Irani, Xiao Li, Qian Zhang, Fansen Meng, Shengduo Liu, Fei Zhang, Liming Wu, Xia Lin, Xiaojian Wang, Jian Zou, Hai Song, Jun Qin, Tingbo Liang, Xin-Hua Feng, Yan Jessie Zhang, Pinglong Xu
Publikováno v:
PLoS Biology, Vol 19, Iss 2, p e3001122 (2021)
The Hippo-YAP pathway responds to diverse environmental cues to manage tissue homeostasis, organ regeneration, tumorigenesis, and immunity. However, how phosphatase(s) directly target Yes-associated protein (YAP) and determine its physiological activ
Externí odkaz:
https://doaj.org/article/1c1a795a50ae4782ad49dfdef46b4e3e
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
The Hippo pathway responds to diverse environmental cues and plays key roles in cell fate determination, tissue homeostasis, and organ regeneration. Aberrant Hippo signaling, on the other hand, has frequently been implicated in diversified pathologie
Externí odkaz:
https://doaj.org/article/cc998bc5cb564be09d0f1879210ed707
Publikováno v:
Journal of Physiology and Biochemistry. 77:461-468
Little is known about the biological functions and underlying mechanisms of long non-coding RNA AFAP1-AS1 in degenerative calcified aortic valve disease (DCAVD). This study aims to explore whether AFAP1-AS1 regulates macrophage polarization in aortic
Publikováno v:
Acta Biochimica et Biophysica Sinica. 52:757-767
Sensing of intracellular and extracellular environments is one of the fundamental processes of cell. Surveillance of aberrant nucleic acids, derived either from invading pathogens or damaged organelle, is conducted by pattern recognition receptors (P
Autor:
Qian Zhang, Shengduo Liu, Chen-Song Zhang, Qirou Wu, Xinyuan Yu, Ruyuan Zhou, Fansen Meng, Ailian Wang, Fei Zhang, Shasha Chen, Xiaojian Wang, Lei Li, Jun Huang, Yao-Wei Huang, Jian Zou, Jun Qin, Tingbo Liang, Xin-Hua Feng, Sheng-Cai Lin, Pinglong Xu
Publikováno v:
Molecular Cell. 82:4519-4536.e7
Nutrient sensing and damage sensing are two fundamental processes in living organisms. While hyperglycemia is frequently linked to diabetes-related vulnerability to microbial infection, how body glucose levels affect innate immune responses to microb
Autor:
Li Shen, Jian Zou, Qingzhe Wu, Shengduo Liu, Shiying Wu, Jun Qin, Songying Ouyang, Fansen Meng, Xin-Hua Feng, Fei Zhang, Xinran Li, Ruyuan Zhou, Jun Huang, Pinglong Xu, Zongping Xia, Hai Song, Qian Zhang
Publikováno v:
Nature Cell Biology. 21:1027-1040
Sensing cytosolic DNA through the cGAS–STING pathway constitutes a widespread innate immune mechanism to monitor cellular damage and microbial invasion. Evading this surveillance is crucial in tumorigenesis, but the process remains largely unexplor
Autor:
Jun Qin, Yan Jessie Zhang, Qirou Wu, Xiaojian Wang, Xin-Hua Feng, Fansen Meng, Pinglong Xu, Mengqiu Wang, Liming Wu, Shengduo Liu, Xia Lin, Fei Zhang, Seema Irani, Xiao Li, Jian Zou, Tingbo Liang, Ruyuan Zhou, Hai Song, Qian Zhang
Publikováno v:
PLoS Biology
PLoS Biology, Vol 19, Iss 2, p e3001122 (2021)
PLoS Biology, Vol 19, Iss 2, p e3001122 (2021)
The Hippo-YAP pathway responds to diverse environmental cues to manage tissue homeostasis, organ regeneration, tumorigenesis, and immunity. However, how phosphatase(s) directly target Yes-associated protein (YAP) and determine its physiological activ
Autor:
Jun Qin, Ruyuan Zhou, Xinran Li, Fansen Meng, Pinglong Xu, Shasha Chen, Jian Zou, Kun-Liang Guan, Shiying Wu, Bin Zhao, Shengduo Liu, Junxian Wang, Qian Zhang, Xin-Hua Feng, Jianming Liu, Steven W. Plouffe
Publikováno v:
Nature cell biology
The Hippo pathway senses cellular conditions and regulates YAP/TAZ to control cellular and tissue homeostasis, while TBK1 is central for cytosolic nucleic acid sensing and antiviral defence. The correlation between cellular nutrient/physical status a
Autor:
Shasha Chen, Shengduo Liu, Zongping Xia, Xinran Li, Qian Zhang, Fansen Meng, Jian Zou, Zhengyang Yu, Qiuheng Jin, Ruyuan Zhou, Xin-Hua Feng, Yao-Wei Huang, Sheng Ye, Lin Hu, Shiying Wu, Pinglong Xu, Li Shen, Siwen Wang
Publikováno v:
Cell hostmicrobe. 21(6)
Cytosolic nucleic acid sensing elicits interferon production for primary antiviral defense through cascades controlled by protein ubiquitination and Ser/Thr phosphorylation. Here we show that TBK1, a core kinase of antiviral pathways, is inhibited by
Autor:
Jian Zou, Yao Zhou, Steven W. Plouffe, Xin-Hua Feng, Kun-Liang Guan, Qiuheng Jin, Ruyuan Zhou, Sheng Ye, Qian Zhang, Pinglong Xu, Hai Song, Shiying Wu, Bin Zhao, Shengduo Liu, Fansen Meng, Zongping Xia
Publikováno v:
Meng, F; Zhou, R; Wu, S; Zhang, Q; Jin, Q; Zhou, Y; et al.(2016). Mst1 shuts off cytosolic antiviral defense through IRF3 phosphorylation. GENES & DEVELOPMENT, 30(9), 1086-1100. doi: 10.1101/gad.277533.116. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/4fs2s75z
Genes & development, vol 30, iss 9
Genes & development, vol 30, iss 9
Cytosolic RNA/DNA sensing elicits primary defense against viral pathogens. Interferon regulatory factor 3 (IRF3), a key signal mediator/transcriptional factor of the antiviral-sensing pathway, is indispensible for interferon production and antiviral
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5345e4e0bd692eda1955b8c2d78158ea
http://www.escholarship.org/uc/item/4fs2s75z
http://www.escholarship.org/uc/item/4fs2s75z