Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Ruwani P Hewawasam"'
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0162415 (2016)
The cardiac ryanodine receptor (RyR2) is an intracellular ion channel that regulates Ca2+ release from the sarcoplasmic reticulum (SR) during excitation-contraction coupling in the heart. The glutathione transferases (GSTs) are a family of phase II d
Externí odkaz:
https://doaj.org/article/6ed2d91727c74af68a1447490b4726f5
Autor:
Jayasinghe Arachchige Nirosha Sandamali, Ruwani Punyakanthi Hewawasam, Madappuli Arachchige Chaminda Sri Sampath Fernando, Kamani Ayoma Perera Wijewardana Jayatilaka
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-17 (2023)
Abstract Background The clinical application of anthracycline chemotherapy is hindered due to the cumulative dose-dependent cardiotoxicity followed by the oxidative stress initiated during the mechanism of action of anthracyclines. Due to a lack of p
Externí odkaz:
https://doaj.org/article/6cbe2ecb4af04a22ad18a19f473f726c
Autor:
Mawanane Hewa Aruna Devapriya de Silva, Ruwani Punyakanthi Hewawasam, Chanika Roshini Kulatunge, Rathnayake Mudiyanselage Anjali Chamika
Publikováno v:
BMC Pediatrics, Vol 22, Iss 1, Pp 1-10 (2022)
Abstract Background Non-alcoholic fatty liver disease (NAFLD) has become the most common liver disease among children with a higher prevalence among obese. Fatty liver index (FLI), an algorithm derived to screen NAFLD using the waist circumference, b
Externí odkaz:
https://doaj.org/article/d84f856fc046493988f0df05fe2ae40e
Autor:
Jayasinghe Arachchige Nirosha Sandamali, Ruwani Punyakanthi Hewawasam, Kamani Ayoma Perera Wijewardana Jayatilaka, Lakmini Kumari Boralugoda Mudduwa
Publikováno v:
Saudi Pharmaceutical Journal, Vol 29, Iss 8, Pp 820-832 (2021)
Anti-tumour efficacy of doxorubicin is hindered by the cumulative dose-dependent cardiotoxicity induced by reactive oxygen species during its metabolism. As Cinnamomum zeylanicum has proven antioxidant potential, objective of this study was to invest
Externí odkaz:
https://doaj.org/article/e080ef11cdcb4510b914fae51c4b6f60
Publikováno v:
The Scientific World Journal, Vol 2022 (2022)
Background. Deposition and formation of stones in any part of the urinary system is called urolithiasis. CaOx is the predominant component of most stones, and the formation of these stones is a multistep process that includes supersaturation, nucleat
Externí odkaz:
https://doaj.org/article/9c306e82a4df4357b7234333c0f85f69
Publikováno v:
International Journal of Pediatrics, Vol 2021 (2021)
Dual-energy X-ray absorptiometry (DXA) is the reference standard in the measurement of body composition indices. But, its utility is limited due to the high cost, expertise required, lack of portability, and restricted availability. Therefore, bioele
Externí odkaz:
https://doaj.org/article/2756cc79972145f282a3f07ce4c386e6
Autor:
Hasanga Rathnayake, Manikkuwadura Hasara Nethmini De Zoysa, Ruwani Punyakanthi Hewawasam, Weerasinghe Mudiyanselage Dilip Gaya Bandara Wijayaratne
Publikováno v:
Scientifica, Vol 2020 (2020)
Methicillin-resistant Staphylococcus aureus (MRSA) is a major cause of hospital- and community-acquired infections worldwide. Therefore, this study was conducted to explore the antibacterial activity of the two medicinal plants Epaltes divaricata and
Externí odkaz:
https://doaj.org/article/8761b798d90347b285a835a75282466f
Autor:
Manikkuwadura Hasara Nethmini De Zoysa, Hasanga Rathnayake, Ruwani Punyakanthi Hewawasam, Weerasinghe Mudiyanselage Dilip Gaya Bandara Wijayaratne
Publikováno v:
International Journal of Microbiology, Vol 2019 (2019)
Introduction. Antibiotic resistance is one of the greatest threats of the 21st century. Scientists search for potential antimicrobial sources that can cope with antibiotic resistance. Plants used in traditional medicine can be identified as potential
Externí odkaz:
https://doaj.org/article/632fd91dcf9945948e27e90766612ca4
Autor:
Jayasinghe A. N. Sandamali, Ruwani P. Hewawasam, Kamani A. P. W. Jayatilaka, Lakmini K. B. Mudduwa
Publikováno v:
Oxidative Medicine and Cellular Longevity.
The therapeutic efficacy of anthracycline antibiotic, doxorubicin (Dox), is hampered due to the dose-dependent cardiotoxicity. The objective of the study was to explore the counteraction of aqueous bark extract of Nauclea orientalis in Dox-induced ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f68d92870a980838f070c5c3d20a3d7
Autor:
Jayasinghe A N, Sandamali, Ruwani P, Hewawasam, Kamani A P W, Jayatilaka, Lakmini K B, Mudduwa
Publikováno v:
Evidence-based Complementary and Alternative Medicine : eCAM
Dose-dependent cardiotoxicity of doxorubicin may lead to irreversible congestive heart failure. Although multiple mechanisms are involved, generation of free radicals is the most commonly postulated mechanism. Therefore, free radical scavengers are c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b21042c404f886b27edc2ca512f208a0
https://pubmed.ncbi.nlm.nih.gov/32308710
https://pubmed.ncbi.nlm.nih.gov/32308710