Zobrazeno 1 - 10
of 371
pro vyhledávání: '"Ruusalepp A"'
Autor:
Hua Gao, Mao Zhang, Richard A. Baylis, Fudi Wang, Johan L.M. Björkegren, Jason J. Kovacic, Arno Ruusalepp, Nicholas J. Leeper
Publikováno v:
STAR Protocols, Vol 5, Iss 1, Pp 102883- (2024)
Summary: The accumulation of omics and biobank resources allows for a genome-wide understanding of the shared pathologic mechanisms between diseases and for strategies to identify drugs that could be repurposed as novel treatments. Here, we present a
Externí odkaz:
https://doaj.org/article/aec9b6c76c0d4355bc39bed0e3b9b685
Autor:
Alfirevic, Andrej, Anton, James M., Antoniou, Theofani, Auci, Elisabetta, Badakhsh, Orode, Banks, Dalia A., Barrio, Jose M., Bartels, Karsten, Belli, Erol V., Bermede, Onat, Bettex, Dominique, Biedermann, Sébastien, Boelsen, Jonas, Boisen, Michael L., Book, Malte, Bottiger, Brandi A., Bouchez, Stefaan, Bräuer, Anselm, Brodt, Jessica L, Chaudhry, Sunit-Preet, Conlin, Frederick T., Cormican, Daniel S., Cristinar, Mircea, Curtis, Michael S., Dalia, Adam A., D'Avino, Emilio, Durand, Michel, Eberle, Balthasar, Emmert, Daniel A., Erb, Joachim M., Falterman, Jason, Forner, Anna Flo, Gatha, Nehal M., Gaudard, Philippe, Giebler, Antasia, Gliga, Louise A., Guarracino, Fabio, Gürcü, Mustafa E., Hans, Gregory A., Hanson, Ross S., Heringlake, Matthias, Hilberath, Jan N., Hommel, Matthias, Huhn, Ragnar, Iyer, Manoj H., Jacquet, Luc M., Karadeniz, Ümit, Kertai, Miklos D., Martin, Archer Kilbourne, Kolarczyk, Lavinia M., Koller, Tobias, Kurian, Dinesh J., Kornfield, Zev N., Koster, Andreas, Kranke, Peter, Krauss, Bernadette, Kudsioglu, Turkan, Kwak, Jenny, Lachauer, Steffen, Lagier, David, Lango, Romuald, Liang, Hong, Lilie, Craig J., Logeman, Elisabeth Angelique, Magunia, Harry, Mahmoud, Saifeldin, Makar, Moody, Markovic, Dejan, Mathis, Michael R., Mattei, Mathieu, Mazzeffi, Michael A., McCabe, Melissa D., Meers, J. Brad, Moitra, Vivek K., Møller-Sørensen, Hasse, Moravcova, Sarka, Muellejans, Bernd, Münch, Christopher M., Murray, Andrew W., Moncho, Azucena Pajares, Ngai, Jennie, Nielsen, Dorthe V., Ortoleva, Jamel P., Ouattara, Alexandre, Patel, Bhoumesh, Paul, Frank, Peng, Yong G., Pittarello, Demetrio, Prabhu, Mahesh, Rancati, Valentina, Rex, Steffen, Riha, Hynek, Robitaille, Mark J., Blanco, Yiliam Rodriguez, Rovira, Irene, Ruusalepp, Arno, Samalavicius, Robertas, Saatee, Siavosh, Sauer, William J., Scheiermann, Patrick, Schlesinger, Rachel E., Schroeder, Andrew M., Schroeder, Sarah E., Shih, Henry, Slaughter, Mark S., Sostaric, Maja, Šribar, Andrej, Svalebjørg, Morten, Székely, Andrea, Szentgyorgyi, Lajos, ter Horst, Maarten, Tschernko, Edda M., Twite, Mark, Ulrichs, Christoph, van der Maaten, Joost M.A.A., van der Ploeg, Nathalie, Vilela, Hugo P., von Homeyer, Peter, Wagner, Nana-Maria, Weiner, Menachem M., Wunder, Christian, Zink, Wolfgang, Kummerow, Maren *, von Dossow, Vera, Pasero, Daniela, Martinez Lopez de Arroyabe, Blanca, Abrams, Benjamin, Kowalsky, Markus, Wilkey, Barbara J., Subramanian, Kathirvel, Martin, Archer K., Marczin, Nandor, de Waal, Eric E.C.
Publikováno v:
In Journal of Cardiothoracic and Vascular Anesthesia January 2024 38(1):197-206
Autor:
Radoslav Savić, Jialiang Yang, Simon Koplev, Mahru C. An, Priyanka L. Patel, Robert N. O’Brien, Brittany N. Dubose, Tetyana Dodatko, Eduard Rogatsky, Katyayani Sukhavasi, Raili Ermel, Arno Ruusalepp, Sander M. Houten, Jason C. Kovacic, Andrew F. Stewart, Christopher B. Yohn, Eric E. Schadt, Remi-Martin Laberge, Johan L.M. Björkegren, Zhidong Tu, Carmen Argmann
Publikováno v:
Cell Reports, Vol 42, Iss 11, Pp 113371- (2023)
Summary: Senescent cells are a major contributor to age-dependent cardiovascular tissue dysfunction, but knowledge of their in vivo cell markers and tissue context is lacking. To reveal tissue-relevant senescence biology, we integrate the transcripto
Externí odkaz:
https://doaj.org/article/1c20f6d542d54b86acc9526737df22b2
Autor:
Sean Bankier, Lingfei Wang, Andrew Crawford, Ruth A. Morgan, Arno Ruusalepp, Ruth Andrew, Johan L. M. Björkegren, Brian R. Walker, Tom Michoel
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
Genome-wide association meta-analysis (GWAMA) by the Cortisol Network (CORNET) consortium identified genetic variants spanning the SERPINA6/SERPINA1 locus on chromosome 14 associated with morning plasma cortisol, cardiovascular disease (CVD), and SER
Externí odkaz:
https://doaj.org/article/0d93e428326e4f94a5933ee714cc2c07
Autor:
Savić, Radoslav, Yang, Jialiang, Koplev, Simon, An, Mahru C., Patel, Priyanka L., O’Brien, Robert N., Dubose, Brittany N., Dodatko, Tetyana, Rogatsky, Eduard, Sukhavasi, Katyayani, Ermel, Raili, Ruusalepp, Arno, Houten, Sander M., Kovacic, Jason C., Stewart, Andrew F., Yohn, Christopher B., Schadt, Eric E., Laberge, Remi-Martin, Björkegren, Johan L.M., Tu, Zhidong, Argmann, Carmen
Publikováno v:
In Cell Reports 28 November 2023 42(11)
Autor:
Kleeman, Sam O., Thakir, Tuba Mansoor, Demestichas, Breanna, Mourikis, Nicholas, Loiero, Dominik, Ferrer, Miriam, Bankier, Sean, Riazat-Kesh, Yosef J.R.A., Lee, Hassal, Chantzichristos, Dimitrios, Regan, Claire, Preall, Jonathan, Sinha, Sarthak, Rosin, Nicole, Yipp, Bryan, de Almeida, Luiz G.N., Biernaskie, Jeff, Dufour, Antoine, Tober-Lau, Pinkus, Ruusalepp, Arno, Bjorkegren, Johan L.M., Ralser, Markus, Kurth, Florian, Demichev, Vadim, Heywood, Todd, Gao, Qing, Johannsson, Gudmundur, Koelzer, Viktor H., Walker, Brian R., Meyer, Hannah V., Janowitz, Tobias
Publikováno v:
In Cell Genomics 9 August 2023 3(8)
Akademický článek
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Autor:
Wang, Ying, Nanda, Vivek, Direnzo, Daniel, Ye, Jianqin, Xiao, Sophia, Kojima, Yoko, Howe, Kathryn L., Jarr, Kai-Uwe, Flores, Alyssa M., Tsantilas, Pavlos, Tsao, Noah, Rao, Abhiram, Newmane, Alexandra A. C., Eberhard, Anne V., Priest, James R., Ruusalepp, Arno, Pasterkamp, Gerard, Maegdefessel, Lars, Miller, Clint L., Lind, Lars, Koplev, Simon, Björkegren, Johan L. M., Owense, Gary K., Ingelsson, Erik, Weissmanr, Irving L., Leeper, Nicholas J.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2020 Jul 01. 117(27), 15818-15826.
Externí odkaz:
https://www.jstor.org/stable/26935148
Autor:
Lijiang Ma, Nicole S Bryce, Adam W Turner, Antonio F Di Narzo, Karishma Rahman, Yang Xu, Raili Ermel, Katyayani Sukhavasi, Valentina d'Escamard, Nirupama Chandel, Bhargavi V'Gangula, Kathryn Wolhuter, Daniella Kadian-Dodov, Oscar Franzen, Arno Ruusalepp, Ke Hao, Clint L Miller, Johan L M Björkegren, Jason C Kovacic
Publikováno v:
PLoS Genetics, Vol 18, Iss 6, p e1010261 (2022)
Genome wide association studies (GWAS) have identified thousands of single nucleotide polymorphisms (SNPs) associated with the risk of common disorders. However, since the large majority of these risk SNPs reside outside gene-coding regions, GWAS gen
Externí odkaz:
https://doaj.org/article/8f50972152a349d08f4369b9b5980542
Autor:
Ariella T. Cohain, William T. Barrington, Daniel M. Jordan, Noam D. Beckmann, Carmen A. Argmann, Sander M. Houten, Alexander W. Charney, Raili Ermel, Katyayani Sukhavasi, Oscar Franzen, Simon Koplev, Carl Whatling, Gillian M. Belbin, Jialiang Yang, Ke Hao, Eimear E. Kenny, Zhidong Tu, Jun Zhu, Li-Ming Gan, Ron Do, Chiara Giannarelli, Jason C. Kovacic, Arno Ruusalepp, Aldons J. Lusis, Johan L. M. Bjorkegren, Eric E. Schadt
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Some cholesterol-lowering drugs can increase the risk of type 2 diabetes, but the mechanism behind this is not fully understood. Here the authors show that there is a single genetic regulatory module that influences both cholesterol levels and glucos
Externí odkaz:
https://doaj.org/article/0c2afd1828064aad921b2b15f3e5c1e2