Zobrazeno 1 - 10
of 105
pro vyhledávání: '"Ruurd van der Zee"'
Autor:
Irene S. Ludwig, Femke Broere, Sarmauli Manurung, Tim T. Lambers, Ruurd van der Zee, Willem van Eden
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Probiotics and probiotic-related nutritional interventions have been described to have beneficial effects on immune homeostasis and gut health. In previous studies, Lactobacillus rhamnosus GG (LGG) soluble mediators (LSM) have been demonstrated to ex
Externí odkaz:
https://doaj.org/article/d07a20664a7c44ae9bc58ca0475f7eb8
Autor:
Willem van Eden, Manon A. A. Jansen, Irene Ludwig, Peter van Kooten, Ruurd van der Zee, Femke Broere
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
The fundamental problem of autoimmune diseases is the failure of the immune system to downregulate its own potentially dangerous cells, which leads to destruction of tissue expressing the relevant autoantigens. Current immunosuppressive therapies off
Externí odkaz:
https://doaj.org/article/9e3e0d196c5244a3baf92494b8a60512
Publikováno v:
PLoS ONE, Vol 12, Iss 5, p e0177365 (2017)
Autoimmune and other chronic inflammatory diseases (AID) are prevalent diseases which can severely impact the quality of life of those that suffer from the disease. In most cases, the etiology of these conditions have remained unclear. Immune respons
Externí odkaz:
https://doaj.org/article/c041d7f361e24f6f9c320cd68da0b468
Autor:
A Charlotte M T de Wolf, Susan van Aalst, Irene S Ludwig, Caroline L Bodinham, David J Lewis, Ruurd van der Zee, Willem van Eden, Femke Broere
Publikováno v:
PLoS ONE, Vol 12, Iss 6, p e0179942 (2017)
Regulatory T cells (Treg) function in the prevention of excessive inflammation and maintenance of immunological homeostasis. However, these cells may also interfere with resolution of infections or with immune reactions following vaccination. Effects
Externí odkaz:
https://doaj.org/article/28a785d4e0214c0c8c43459be75ea79c
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0128373 (2015)
Therapeutic peptides that target antigen-specific regulatory T cells (Tregs) can suppress experimental autoimmune diseases. The heat shock protein (Hsp) 70, with its expression elevated in inflamed tissue, is a suitable candidate antigen because admi
Externí odkaz:
https://doaj.org/article/b3b6fef5770d4508a88ae47b09fa5f46
Autor:
Rachel Spiering, Ruurd van der Zee, Josée Wagenaar, Dimos Kapetis, Francesca Zolezzi, Willem van Eden, Femke Broere
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e46336 (2012)
Tolerogenic dendritic cells (DCs) can induce regulatory T cells and dampen pathogenic T cell responses. Therefore, they are possible therapeutic targets in autoimmune diseases. In this study we investigated whether mouse tolerogenic DCs are induced b
Externí odkaz:
https://doaj.org/article/de0de426dad7468590871997368f6c9f
Autor:
Joost A Aalberse, Berber Kapitein, Sytze de Roock, Mark R Klein, Wilco de Jager, Ruurd van der Zee, Maarten O Hoekstra, Femke van Wijk, Berent J Prakken
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e24119 (2011)
BACKGROUND: To prevent harmful autoimmunity most immune responses to self proteins are controlled by central and peripheral tolerance. T cells specific for a limited set of self-proteins such as human heat shock protein 60 (HSP60) may contribute to p
Externí odkaz:
https://doaj.org/article/655d914378b049f98944337f9f9b636e
Publikováno v:
PLoS ONE, Vol 6, Iss 11, p e26684 (2011)
Development of vaccines in autoimmune diseases has received wide attention over the last decade. However, many vaccines showed limited clinical efficacy. To enhance vaccine efficacy in infectious diseases, biocompatible and biodegradable polymeric na
Externí odkaz:
https://doaj.org/article/8e1c863091c8419b82a1933cf04f5fc4
Autor:
Lotte Wieten, Suzanne E Berlo, Corlinda B Ten Brink, Peter J van Kooten, Mahavir Singh, Ruurd van der Zee, Tibor T Glant, Femke Broere, Willem van Eden
Publikováno v:
PLoS ONE, Vol 4, Iss 1, p e4186 (2009)
BACKGROUND: The anti-inflammatory capacity of heat shock proteins (HSP) has been demonstrated in various animal models of inflammatory diseases and in patients. However, the mechanisms underlying this anti-inflammatory capacity are poorly understood.
Externí odkaz:
https://doaj.org/article/e6e917b67c8745eb8c512bc868124ff6
