Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Ruud van Oorschot"'
GABA(A) receptor α subunits differentially contribute to diazepam tolerance after chronic treatment.
Autor:
Christiaan H Vinkers, Ruud van Oorschot, Elsebet Ø Nielsen, James M Cook, Henrik H Hansen, Lucianne Groenink, Berend Olivier, Naheed R Mirza
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e43054 (2012)
Within the GABA(A)-receptor field, two important questions are what molecular mechanisms underlie benzodiazepine tolerance, and whether tolerance can be ascribed to certain GABA(A)-receptor subtypes.We investigated tolerance to acute anxiolytic, hypo
Externí odkaz:
https://doaj.org/article/5ee477737fd54740b0f36ab1931d5e23
Autor:
Hendrikus Hendriksen, Sundari K. Rallipalli, Christiaan H. Vinkers, Millan Mark, Lucianne Groenink, James M. Cook, Shengming Huang, Berend Olivier, Ruud van Oorschot
Publikováno v:
Psychopharmacology
Rationale Repeated activation of corticotropin-releasing factor (CRF) receptors is associated with increased anxiety and enhanced stress responsivity, which may be mediated via limbic GABAergic and glutamatergic transmission. Objective The present st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70baee7ecd0075261f9df733d03c3f6e
https://doi.org/10.1007/s00213-011-2423-0
https://doi.org/10.1007/s00213-011-2423-0
Autor:
Christiaan H. Vinkers, Berend Olivier, Lucianne Groenink, Noëlle M. de Jong, Ruud van Oorschot, Koen G.C. Westphal, Cor J. Kalkman, S. Mechiel Korte
Publikováno v:
Pharmacology Biochemistry and Behavior. 93:413-418
Background Stress-induced hyperthermia (SIH) is the transient rise in body temperature after encountering a stressor. The SIH response can be blocked by administration of various anxiolytic drugs prior to inducing stress. However, a drug injection in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97d73eb3936eec280dfc73d1e64577dc
https://doi.org/10.1016/j.pbb.2009.05.017
https://doi.org/10.1016/j.pbb.2009.05.017
Autor:
S. Mechiel Korte, Ruud van Oorschot, Christiaan H. Vinkers, Koen G.C. Westphal, Berend Olivier, Cor J. Kalkman, Lucianne Groenink, Ronald S. Oosting, Meg J.V. van Bogaert
Publikováno v:
Physiology & Behavior. 98:37-43
Stress exposure activates the autonomic nervous system and leads to a body temperature increase (stress-induced hyperthermia, SIH). On the other hand, an activation of the immune system in response to an infection leads to fever. Both processes incre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::353ac7f690191aad787d35b910b0e6a3
https://doi.org/10.1016/j.physbeh.2009.04.004
https://doi.org/10.1016/j.physbeh.2009.04.004
Autor:
Ruud van Oorschot, Berend Olivier
Publikováno v:
European Journal of Pharmacology. 526:207-217
The serotonergic (5-HT) system in the brain is involved in the modulation of offensive aggressive behavior. The dogma that activity of the 5-HT system is inversely related to aggression is obsolete now. Research on the status of the 5-HT system befor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f905933876d807f6d84b76b002e926a
https://doi.org/10.1016/j.ejphar.2005.09.066
https://doi.org/10.1016/j.ejphar.2005.09.066
Autor:
Arjan Bouwknecht, Ronald S. Oosting, Lucianne Groenink, Jan van der Gugten, Tommy Pattij, Berend Olivier, Ruud van Oorschot, Jan G. Veening, Christina Leahy, Theo J.J. Zethof, Meg van Boogaert
Publikováno v:
European Journal of Pharmacology, 463, 117-32
European Journal of Pharmacology, 463, 1-3, pp. 117-32
Olivier, B, Zethof, T, Pattij, T, Van Boogaert, M, Van Oorschot, R, Leahy, C, Oosting, R, Bouwknecht, A, Veening, J, Van Der Gugten, J & Groenink, L 2003, ' Stress-induced hyperthermia and anxiety : Pharmacological validation ', European Journal of Pharmacology, vol. 463, no. 1-3, pp. 117-132 . https://doi.org/10.1016/S0014-2999(03)01326-8
European Journal of Pharmacology, 463, 1-3, pp. 117-32
Olivier, B, Zethof, T, Pattij, T, Van Boogaert, M, Van Oorschot, R, Leahy, C, Oosting, R, Bouwknecht, A, Veening, J, Van Der Gugten, J & Groenink, L 2003, ' Stress-induced hyperthermia and anxiety : Pharmacological validation ', European Journal of Pharmacology, vol. 463, no. 1-3, pp. 117-132 . https://doi.org/10.1016/S0014-2999(03)01326-8
When mammals, including man, are confronted with a stressful event, their core body temperature rises, stress-induced hyperthermia. In mice, the stress-induced hyperthermia procedure has been developed to measure antistress or anxiolytic-like effects
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1cc9177d3e07868628782945bf4d244
https://doi.org/10.1016/s0014-2999(03)01326-8
https://doi.org/10.1016/s0014-2999(03)01326-8
Autor:
Tommy Pattij, Afke van de Plas, Marcel D. Waldinger, Ruud van Oorschot, Lique M. Coolen, Jan G. Veening, Berend Olivier
Publikováno v:
Psychopharmacology, 160(3), 283-289. Springer Verlag
Psychopharmacology, 160, 3, pp. 283-9
Waldinger, M D, Van de Plas, A, Pattij, T, Van Oorschot, R, Coolen, L M, Veening, J G & Olivier, B 2002, ' The selective serotonin re-uptake inhibitors fluvoxamine and paroxetine differ in sexual inhibitory effects after chronic treatment ', Psychopharmacology, vol. 160, no. 3, pp. 283-289 . https://doi.org/10.1007/s00213-001-0980-3
Psychopharmacology, 160, 283-9
Psychopharmacology, 160, 3, pp. 283-9
Waldinger, M D, Van de Plas, A, Pattij, T, Van Oorschot, R, Coolen, L M, Veening, J G & Olivier, B 2002, ' The selective serotonin re-uptake inhibitors fluvoxamine and paroxetine differ in sexual inhibitory effects after chronic treatment ', Psychopharmacology, vol. 160, no. 3, pp. 283-289 . https://doi.org/10.1007/s00213-001-0980-3
Psychopharmacology, 160, 283-9
Item does not contain fulltext RATIONALE: The selective serotonin re-uptake inhibitors (SSRIs) delay orgasm and ejaculation in men. In men with rapid ejaculation it was shown that, of the SSRIs, paroxetine exerted the strongest delay in ejaculation a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::febe94a9002d22dfed4a962ad64eae27
https://doi.org/10.1007/s00213-001-0980-3
https://doi.org/10.1007/s00213-001-0980-3
Publikováno v:
Neuropraxis. 4:1-6
Agressie wordt tegenwoordig omschreven als de bewuste intentie om anderen pijn, vernedering of schade te berokkenen, terwijl dit door hen ook als zodanig wordt ervaren. Deze definitie is echter geenszins sluitend voor humane agressie omdat in de mens
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::988fd8d04e5b69897a944b138cf68468
https://doi.org/10.1007/bf03078954
https://doi.org/10.1007/bf03078954
Autor:
Berend Olivier, Jan Mos, Theo H. Hijzen, Arnoud H.J. Herremans, Ruud van Oorschot, Martin Tulp, Marlies L. Van Drimmelen
Publikováno v:
Pharmacology Biochemistry and Behavior. 64:421-427
Twelve pigeons were successfully (ED 50 = 2.4 mg/kg PO) trained to discriminate the 5-HT 1A/B receptor agonist eltoprazine (5.0 mg/kg PO) from its vehicle in a fixed-ratio (FR)30 two-key operant drug discrimination procedure. Tests for generalization
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2557da0af786244723d68e610d099fb
https://doi.org/10.1016/s0091-3057(99)00073-8
https://doi.org/10.1016/s0091-3057(99)00073-8
Publikováno v:
European Neuropsychopharmacology. 6:1-7
The behavioral effects of eltoprazine and haloperidol during a 4 week treatment period were studied in the resident-intruder model of aggression in male rats. Eltoprazine, a serotonergic (5-HT1A/1B) agonist with specific anti-aggressive actions in an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50b887f22e8ac6696806c32e29c76283
https://doi.org/10.1016/0924-977x(95)00051-p
https://doi.org/10.1016/0924-977x(95)00051-p