Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Ruud Verrijk"'
Autor:
Nanno F A W Peek, Marja J Nell, Ronald Brand, Thekla Jansen-Werkhoven, Ewoud J van Hoogdalem, Ruud Verrijk, Marcel J Vonk, Amon R Wafelman, A Rob P M Valentijn, Johan H M Frijns, Pieter S Hiemstra, Jan W Drijfhout, Peter H Nibbering, Jan J Grote
Publikováno v:
PLoS ONE, Vol 15, Iss 4, p e0231573 (2020)
OBJECTIVE:Chronic suppurative otitis media (CSOM) is a chronic infectious disease with worldwide prevalence that causes hearing loss and decreased quality of life. As current (antibiotic) treatments often unsuccessful and antibiotic resistance is eme
Externí odkaz:
https://doaj.org/article/016758d3e2bf487cacaca5ca149296a8
Autor:
S. K. D. Waasdorp, Wim Jiskoot, Jelte Meulenaar, Ruud Verrijk, Ahmad S. Sediq, M. R. Nejadnik, M. M. C. van Beers
Publikováno v:
Pharmaceutical Research
PHARMACEUTICAL RESEARCH, 34(5), 1104-1114
PHARMACEUTICAL RESEARCH, 34(5), 1104-1114
Purpose To investigate whether particle sedimentation velocity tracking using a flow imaging microscope (FlowCAM) can be used to determine microparticle porosity. Methods Two different methods were explored. In the first method the sedimentation rate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::745fe137f55e389f82b75000e8c37942
https://doi.org/10.1007/s11095-017-2120-8
https://doi.org/10.1007/s11095-017-2120-8
Autor:
Cees Slooten, Wim Jiskoot, Jelte Meulenaar, Ruud Verrijk, Ahmad S. Sediq, Miranda M. C. van Beers
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics
European Journal of Pharmaceutics and Biopharmaceutics, 117, 91–104
European Journal of Pharmaceutics and Biopharmaceutics, 117, 91–104
The purpose of this study was to explore the potential of flow imaging microscopy to measure particle size and agglomeration of poly(lactic-co-glycolic acid) (PLGA) microparticles. The particle size distribution of pharmaceutical PLGA microparticle p
Autor:
Justyna Korczynska, Lemy Tsikna, Zoe Hughes-Thomas, Richard Haworth, Christopher J. Roberts, John Warrack, Steven D. Sorden, Irene Papanicolaou, Rodd Polsky, Eric Dobrzynski, Edit Kurali, Timothy Streit, Thomas Wilde, Jeffery J Prusakiewicz, Brian J Christian, Peter C. Adamson, T Michael Nork, Ian Richard Catchpole, Craig Struble, Caroline Sychterz, James Walford, Chi-Man Tang, Daniel Gibson, Ruud Verrijk, Paul E. Miller, Fiona Cook, Jos Smal
Publikováno v:
Journal of controlled release : official journal of the Controlled Release Society
A potent anti-vascular endothelial growth factor (VEGF) biologic and a compatible delivery system were co-evaluated for protection against wet age-related macular degeneration (AMD) over a 6month period following a single intravitreal (IVT) injection
Autor:
Wim E. Hennink, Cornelus F. van Nostrum, Leo G.J. de Leede, Johan Kemmink, Pascal H.J.L.F. de Jong, Ruud Verrijk, Daan J.A. Crommelin, Myrra G. Carstens
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 68:596-606
Docetaxel (DCTX) and paclitaxel (PTX) are very potent anti-cancer drugs, but the currently marketed formulations, Taxotere ® and Taxol ® , respectively, are associated with vehicle-related toxicity. An attractive alternative to formulate these hydr
Autor:
Heleen M.M. van Beusekom, Ilona Krabbendam-Peters, Rorry van Haeren, Willem J. van der Giessen, Tommi Markkula, Tirza Springeling, Richard W. B. van Duin, Stefan Sneep, Matthijs van Kranenburg, Charlotte Gorsse-Bakker, Robert-Jan van Geuns, André Uitterdijk, Ruud Verrijk, Dirk J. Duncker
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology, 309(3), H396-H406. American Physiological Society
Angiogenesis induced by growth factor-releasing microspheres can be an off-the-shelf and immediate alternative to stem cell therapy for acute myocardial infarction (AMI), independent of stem cell yield and comorbidity-induced dysfunction. Reliable an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f4176259251f3670e3c92a3bbdc89d7
https://pure.eur.nl/en/publications/e028c2c1-16f4-474d-a275-0567c1441463
https://pure.eur.nl/en/publications/e028c2c1-16f4-474d-a275-0567c1441463
Autor:
Mies J. van Steenbergen, Cornelus F. van Nostrum, Leo G.J. de Leede, Frits M. Flesch, Myrra G. Carstens, Jan J. L. Bevernage, Daan J.A. Crommelin, Ruud Verrijk, Wim E. Hennink
Publikováno v:
Macromolecules. 40:116-122
To design stable biodegradable micelles with a size smaller than 20 nm, the self-assembly of methoxypoly(ethylene glycol)-b-oligocaprolactones (mPEG-b-OCLs), and the effect of OCL block length and ...
Autor:
Wim E. Hennink, Wim Jiskoot, K.D.F. Vlugt-Wensink, Ruud Verrijk, Thijs J. H. Vlugt, Daan J.A. Crommelin
Publikováno v:
Journal of Controlled Release. 111:117-127
To optimize and predict the release of proteins from biodegradable microspheres based on crosslinked dextran, a fundamental understanding of the mechanisms controlling their release is necessary. For that purpose, a mathematical model has been develo
Publikováno v:
International Journal of Pharmaceutics. 266:3-16
Biopharmaceuticals are pharmaceutical products consisting of (glyco)proteins. Nowadays a substantial part of the FDA-approved drugs belong to this class of drugs. Biopharmaceuticals deserve special attention as they have a number of characteristics t
Autor:
Leo G.J. de Leede, Anne C. Bechet, Ewoud J. van Hoogdalem, John Elliott Humphries, Ruud Verrijk, David Gelvin. Spencer
Publikováno v:
Journal of interferoncytokine research : the official journal of the International Society for Interferon and Cytokine Research. 28(2)
Locteron, a newly developed controlled-release formulation of Lemna-derived free (unpegylated) recombinant interferon-alpha2b (IFN-alpha2b, Biolex Therapeutics, Pittsboro, NC) in poly(ether-ester) microspheres (PolyActive, OctoPlus N.V., Leiden, the