Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Ruud Leemans"'
Autor:
Steven Nijs, Thomas N. Kakuda, Veerle Vyncke, Monika Peeters, Goedele De Smedt, Richard M. W. Hoetelmans, Lorant Leopold, Ruud Leemans, Cindy Berckmans, Rodica Van Solingen-Ristea
Publikováno v:
Int. Journal of Clinical Pharmacology and Therapeutics. 51:725-736
Objectives Three studies were conducted to assess the pharmacokinetics, methods of administration and ease of swallowability of etravirine tablets. Methods Two randomized studies in healthy adults investigated the single-dose pharmacokinetics of etra
Autor:
Ruud Leemans, Sheng Qi, Sigrid Stokbroekx, Ilse Weuts, Mike Reading, Duncan Q.M. Craig, Steve De Cort, Peter S. Belton
Publikováno v:
Journal of Pharmaceutical Sciences. 99:196-208
The aim of this study was to evaluate the glass transition and recrystallisation of a cryomilled drug, TMC125 (Etravirine), with particular emphasis on assessing the physical stability of the drug above and below the glass transition temperature. DSC
Autor:
Carlo Giaquinto, Ruud Leemans, Rebecca Mack, Christoph Königs, Claudio Viscoli, Thomas N. Kakuda, Raffaella Rosso, Ingeborg Peeters, Monika Peeters, Katia Boven, Rekha Sinha, Susanna Esposito, Cornelia Feiterna-Sperling
OBJECTIVES To evaluate the pharmacokinetics, weight-based dose selection and short-term safety and tolerability of etravirine in HIV-1-infected children and adolescents. DESIGN Phase I, nonrandomized, open-label study in two stages. METHODS Children
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cc4d2e2c4de2600908096b949072823
http://hdl.handle.net/11577/2802500
http://hdl.handle.net/11577/2802500
Autor:
Thomas N. Kakuda, Ann Debunne, Ruud Leemans, Brian Woodfall, Marie-Pierre de Béthune, Michael Joseph Kukla, Koen Andries, Johan Vingerhoets
Publikováno v:
Antiviral Drugs: From Basic Discovery through Clinical Trials
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4bc9ec6313e5b84a25c24840a2a79846
https://doi.org/10.1002/9780470929353.ch6
https://doi.org/10.1002/9780470929353.ch6
Autor:
Monika Peeters, Thomas N. Kakuda, Veerle Vyncke, Marta Boffito, Brian Woodfall, Monika Schöller-Gyüre, Richard M. W. Hoetelmans, Kati Vandermeulen, Ruud Leemans, Anton L Pozniak
Publikováno v:
Pharmacotherapy. 28(10)
Study Objective. To determine the effects of various meal compositions and the fasted state on the pharmacokinetics of etravirine, a nonnucleoside reverse transcriptase inhibitor. Design. Phase I, open-label, randomized, repeated single-dose, three-p