Zobrazeno 1 - 10
of 167
pro vyhledávání: '"Ruud L.M. Bekkers"'
Autor:
Stephanie W. Vrede, Hannah Donkers, Casper Reijnen, Anke Smits, Nicole C.M. Visser, Peggy M. Geomini, Huy Ngo, Dennis van Hamont, Brenda M. Pijlman, Maria Caroline Vos, Marc P.L.M. Snijders, Roy Kruitwagen, Ruud L.M. Bekkers, Khadra Galaal, Johanna M.A. Pijnenborg
Publikováno v:
Journal of Obstetrics and Gynaecology, Vol 44, Iss 1 (2024)
Background In endometrial cancer (EC), preoperative anaemia, thrombocytosis and leucocytosis appear to be associated with worse prognosis. It remains unclear whether these parameters solely reflect tumour aggressiveness, or also impact response to ad
Externí odkaz:
https://doaj.org/article/47c1e1cca20140df8cdf7eeb83eb6baa
Autor:
Federica Inturrisi, Clare A. Aitken, Willem J.G. Melchers, Adriaan J.C. van den Brule, Anco Molijn, John W.J. Hinrichs, Hubert G.M. Niesters, Albert G. Siebers, Rob Schuurman, Daniëlle A.M. Heideman, Inge M.C.M. de Kok, Ruud L.M. Bekkers, Folkert J. van Kemenade, Johannes Berkhof
Publikováno v:
The Lancet Regional Health. Europe, Vol 11, Iss , Pp 100235- (2021)
Background: High-risk human papillomavirus (hrHPV) testing on self-collected samples has potential as a primary screening tool in cervical screening, but real-world evidence on its accuracy in hrHPV-based screening programmes is lacking. Methods: In
Externí odkaz:
https://doaj.org/article/4cc9b937a2b341cfba264de00ab94f81
Autor:
Tirza Wouters, Natasja Hendriks, Margot Koeneman, Arnold-Jan Kruse, Anna van de Sande, Heleen J. van Beekhuizen, Kees G. Gerestein, Ruud L.M. Bekkers, Jurgen M.J. Piek
Publikováno v:
Case Reports in Women's Health, Vol 21, Iss , Pp - (2019)
Treatment for cervical intraepithelial neoplasia (CIN) often consists of an excisional procedure. However, less invasive treatment methods have been explored, such as topical treatment with imiquimod cream. Imiquimod has been proven to be effective i
Externí odkaz:
https://doaj.org/article/e1a7bfc0c1874c17addc22d35cba48ea
Autor:
Hans H.B. Wenzel, Anna N. Hardie, Arturo Moncada-Torres, Claus K. Høgdall, Ruud L.M. Bekkers, Henrik Falconer, Pernille T. Jensen, Hans W. Nijman, Maaike A. van der Aa, Frank Martin, Anna J. van Gestel, Valery E.P.P. Lemmens, Pernilla Dahm-Kähler, Emilia Alfonzo, Jan Persson, Linnea Ekdahl, Sahar Salehi, Ligita P. Frøding, Algirdas Markauskas, Katrine Fuglsang, Tine H. Schnack
Publikováno v:
Wenzel, H H B, Hardie, A N, Moncada-Torres, A, Høgdall, C K, Bekkers, R L M, Falconer, H, Jensen, P T, Nijman, H W, van der Aa, M A, Martin, F, van Gestel, A J, Lemmens, V E P P, Dahm-Kähler, P, Alfonzo, E, Persson, J, Ekdahl, L, Salehi, S, Frøding, L P, Markauskas, A, Fuglsang, K & Schnack, T H 2023, ' A federated approach to identify women with early-stage cervical cancer at low risk of lymph node metastases ', European Journal of Cancer, vol. 185, pp. 61-68 . https://doi.org/10.1016/j.ejca.2023.02.021
European Journal of Cancer, 185, 61-68. Elsevier Ltd.
European Journal of Cancer, 185, 61-68. Elsevier Ltd.
OBJECTIVE: Lymph node metastases (pN+) in presumed early-stage cervical cancer negatively impact prognosis. Using federated learning, we aimed to develop a tool to identify a group of women at low risk of pN+, to guide the shared decision-making proc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f3a5ae0ef636bab7530ed4548aab730
https://pure.au.dk/portal/da/publications/a-federated-approach-to-identify-women-with-earlystage-cervical-cancer-at-low-risk-of-lymph-node-metastases(53222236-a198-489c-a4ac-d5c1c2947e6d).html
https://pure.au.dk/portal/da/publications/a-federated-approach-to-identify-women-with-earlystage-cervical-cancer-at-low-risk-of-lymph-node-metastases(53222236-a198-489c-a4ac-d5c1c2947e6d).html
Autor:
Renske D.M. Steenbergen, Chris J.L.M. Meijer, Mark A. van de Wiel, Johannes Berkhof, Folkert J. van Kemenade, Willem J.G. Melchers, Ruud L.M. Bekkers, Leon F.A.G. Massuger, Nienke E. van Trommel, Carel F.W. Peeters, Annina P. van Splunter, Putri W. Novianti, Peter J.F. Snijders, Saskia M. Wilting, Daniëlle A.M. Heideman, Barbara C. Snoek, Wina Verlaat
Further detailed description of methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2494bcb6803b68ad1af414b32ecdad98
https://doi.org/10.1158/1078-0432.22470509
https://doi.org/10.1158/1078-0432.22470509
Autor:
Renske D.M. Steenbergen, Chris J.L.M. Meijer, Mark A. van de Wiel, Johannes Berkhof, Folkert J. van Kemenade, Willem J.G. Melchers, Ruud L.M. Bekkers, Leon F.A.G. Massuger, Nienke E. van Trommel, Carel F.W. Peeters, Annina P. van Splunter, Putri W. Novianti, Peter J.F. Snijders, Saskia M. Wilting, Daniëlle A.M. Heideman, Barbara C. Snoek, Wina Verlaat
Supplementary Figure S1: Overview of study populations. Supplementary Figure S2: Correlation heatmap of all 72 hrHPV-positive self-samples analyzed by Infinium Methylation 450K Array. Supplementary Figure S3: The effect of informative co-data. Supple
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ee00f02b7dc102608d13d2ea2b1e421
https://doi.org/10.1158/1078-0432.22470512
https://doi.org/10.1158/1078-0432.22470512
Autor:
Renske D.M. Steenbergen, Chris J.L.M. Meijer, Mark A. van de Wiel, Johannes Berkhof, Folkert J. van Kemenade, Willem J.G. Melchers, Ruud L.M. Bekkers, Leon F.A.G. Massuger, Nienke E. van Trommel, Carel F.W. Peeters, Annina P. van Splunter, Putri W. Novianti, Peter J.F. Snijders, Saskia M. Wilting, Daniëlle A.M. Heideman, Barbara C. Snoek, Wina Verlaat
Purpose: Offering self-sampling of cervico-vaginal material for high-risk human papillomavirus (hrHPV) testing is an effective method to increase the coverage in cervical screening programs. Molecular triage directly on hrHPV-positive self-samples fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::168f750168df7e82353ef04137d126e8
https://doi.org/10.1158/1078-0432.c.6527594
https://doi.org/10.1158/1078-0432.c.6527594
Autor:
Ruud L.M. Bekkers, Phyllis van der Ploeg, Sandrina Lambrechts, Jurgen M.J. Piek, Hans M. Westgeest, Anna M.J. Thijs, Aniek Uittenboogaard, Anja van de Stolpe, Ingrid A. Boere
Publikováno v:
Gynecologic Oncology, 163(2), 433-444. Elsevier Science
Objective. To determine the clinical benefit of monotherapy with PI3K/AKT/mTOR inhibitors in patients diagnosed with advanced or recurrent ovarian cancer and to investigate the predictive value of current PI3K/AKT/ mTOR biomarkers on therapy response
Autor:
Renske D.M. Steenbergen, Maaike C G Bleeker, Lisanne Verhoef, Wim Quint, Chris J.L.M. Meijer, Nicole J Polman, Daniëlle A M Heideman, Ruud L.M. Bekkers, Folkert J. van Kemenade, Johannes Berkhof, Anco Molijn, Willem J. G. Melchers
Publikováno v:
International Journal of Cancer. 150:440-449
Methylation of host-cell deoxyribonucleic acid (DNA) has been proposed as a promising biomarker for triage of high-risk (hr) human papillomavirus (HPV) positive women at screening. Our study aims to validate recently identified host-cell DNA methylat
Autor:
Ruud L.M. Bekkers, Marjolein Hermens, Johan Bulten, Albert G. Siebers, Huib A.A.M. van Vliet, Anne M. van Altena
Publikováno v:
Gynecologic Oncology, 162, 735-740
Gynecologic Oncology, 162(3), 735-740. Elsevier Science
Gynecologic Oncology, 162, 3, pp. 735-740
Gynecologic Oncology, 162(3), 735-740. Elsevier Science
Gynecologic Oncology, 162, 3, pp. 735-740
Objective. Assessing the association between endometriosis and/or adenomyosis and ovarian cancer. Methods. We identified all women with histological proven endometriosis (51,544 women) and/or adenomyosis (85,015 women) from the Dutch pathology databa