Zobrazeno 1 - 10
of 211
pro vyhledávání: '"Ruud A. Bank"'
Autor:
Nataly Puerta Cavanzo, Sophie A. Riesmeijer, Iris L. Holt-Kedde, Paul M. N. Werker, Bram Piersma, Peter Olinga, Ruud A. Bank
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)
Abstract Dupuytren’s disease is a chronic, progressive fibroproliferative condition of the hand fascia which results in digital contraction. So far, treatments do not directly interfere with the (myo)fibroblasts that are responsible for the formati
Externí odkaz:
https://doaj.org/article/686b76e24d904eaaaf0d16754775ab61
Autor:
Daan C.J. Mohede, MD, Igle Jan de Jong, MD, PhD, Ruud A. Bank, PhD, Mels F. van Driel, MD, PhD
Publikováno v:
Sexual Medicine, Vol 6, Iss 4, Pp 302-308 (2018)
Introduction: In Europe and the United States, verteporfin (Visudyne; VP) is registered and used in treating macular degeneration. Research showed that VP decreased expression of fibrotic genes in fibroblasts collected from nodules of patients suffer
Externí odkaz:
https://doaj.org/article/94d2a623b3444fc984ac58b7a587cf73
Publikováno v:
Frontiers in Medicine, Vol 7 (2021)
An unsolved therapeutic problem in fibrosis is the overproduction of collagen. In order to screen the effect of anti-fibrotic drugs on collagen deposition, the Scar-in-a-Jar approach has been introduced about a decade ago. With macromolecular crowdin
Externí odkaz:
https://doaj.org/article/b26db37c766342768d57a216cf62e413
Autor:
Wouter Tobias van Haaften, Tjasso Blokzijl, Hendrik Sijbrand Hofker, Peter Olinga, Gerard Dijkstra, Ruud A. Bank, Miriam Boersema
Publikováno v:
Therapeutic Advances in Gastroenterology, Vol 13 (2020)
Background and Aims: Crohn’s disease (CD) can be complicated by intestinal fibrosis. Pharmacological therapies against intestinal fibrosis are not available. The aim of this study was to determine whether pathways involved in collagen metabolism ar
Externí odkaz:
https://doaj.org/article/9e48b0b11a31439f91188307e7e9da02
Autor:
Rutger A. F. Gjaltema, Désirée Goubert, Christian Huisman, Consuelo del Pilar García Tobilla, Mihály Koncz, Pytrick G. Jellema, Dandan Wu, Uilke Brouwer, Antal Kiss, Pernette J. Verschure, Ruud A. Bank, Marianne G. Rots
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 10, p 3634 (2020)
Epigenetic editing, an emerging technique used for the modulation of gene expression in mammalian cells, is a promising strategy to correct disease-related gene expression. Although epigenetic reprogramming results in sustained transcriptional modula
Externí odkaz:
https://doaj.org/article/5d79f594822e425a9a45ea409f5d9dc4
Autor:
Emilia Bigaeva, Nataly Puerta Cavanzo, Elisabeth G. D. Stribos, Amos J. de Jong, Carin Biel, Henricus A. M. Mutsaers, Michael S. Jensen, Rikke Nørregaard, Anna M. Leliveld, Igle J. de Jong, Jan-Luuk Hillebrands, Harry van Goor, Miriam Boersema, Ruud A. Bank, Peter Olinga
Publikováno v:
Pharmaceutics, Vol 12, Iss 5, p 459 (2020)
Animal models are a valuable tool in preclinical research. However, limited predictivity of human biological responses in the conventional models has stimulated the search for reliable preclinical tools that show translational robustness. Here, we us
Externí odkaz:
https://doaj.org/article/88f984b7474147c889380ff361af2440
Autor:
Ruud A. Bank, Bram Piersma
Publikováno v:
Essays in Biochemistry. 63:377-387
The hallmark of fibrosis is an excessive accumulation of collagen, ultimately leading to organ failure. It has become evident that the deposited collagen also exhibits qualitative modifications. A marked modification is the increased cross-linking, l
Publikováno v:
Sexual Medicine, Vol 6, Iss 4, Pp 302-308 (2018)
Sexual Medicine
Sexual medicine, 6(4), 302-308. ELSEVIER SCI LTD
Sexual Medicine
Sexual medicine, 6(4), 302-308. ELSEVIER SCI LTD
Introduction In Europe and the United States, verteporfin (Visudyne; VP) is registered and used in treating macular degeneration. Research showed that VP decreased expression of fibrotic genes in fibroblasts collected from nodules of patients sufferi
Autor:
Svenja Sydor, Ruud A. Bank, Natalia Smith-Cortinez, Janette Heegsma, Dirk R. de Waart, Defu Kong, Klaas Nico Faber, Raphael R. Fagundes, Coen C. Paulusma, Vincent E de Meijer, Peter Olinga, Cormac T. Taylor, Valentina Gomez
Publikováno v:
FASEB journal, 35(2):e21219. FASEB
The FASEB Journal, 35(2):e21219. FEDERATION AMER SOC EXP BIOL
The FASEB Journal, 35(2):e21219. FEDERATION AMER SOC EXP BIOL
Liver fibrosis is characterized by the accumulation of extracellular matrix proteins, mainly composed of collagen. Hepatic stellate cells (HSCs) mediate liver fibrosis by secreting collagen. Vitamin C (ascorbic acid) is a cofactor of prolyl-hydroxyla
Publikováno v:
Frontiers in Medicine
Frontiers in Medicine, 7:615774. Frontiers Media S.A.
Frontiers in Medicine, Vol 7 (2021)
Frontiers in Medicine, 7:615774. Frontiers Media S.A.
Frontiers in Medicine, Vol 7 (2021)
An unsolved therapeutic problem in fibrosis is the overproduction of collagen. In order to screen the effect of anti-fibrotic drugs on collagen deposition, the Scar-in-a-Jar approach has been introduced about a decade ago. With macromolecular crowdin