Zobrazeno 1 - 10
of 78
pro vyhledávání: '"Ruud Hovius"'
Autor:
Naemi Luithle, Jelmi uit de Bos, Ruud Hovius, Daria Maslennikova, Renard TM Lewis, Rosemarie Ungricht, Beat Fierz, Ulrike Kutay
Publikováno v:
eLife, Vol 9 (2020)
The inner nuclear membrane is functionalized by diverse transmembrane proteins that associate with nuclear lamins and/or chromatin. When cells enter mitosis, membrane-chromatin contacts must be broken to allow for proper chromosome segregation; yet h
Externí odkaz:
https://doaj.org/article/679c993e628941b28e46150ce42c759e
Autor:
Luigino Grasso, Romain Wyss, Joachim Piguet, Michael Werner, Ghérici Hassaïne, Ruud Hovius, Horst Vogel
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e70929 (2013)
Cellular signaling is classically investigated by measuring optical or electrical properties of single or populations of living cells. Here we show that ligand binding to cell surface receptors and subsequent activation of signaling cascades can be m
Externí odkaz:
https://doaj.org/article/183eec693dad49f686f92c7c99941904
Autor:
Sarah C. R. Lummis, Alexander Roberts, Kathryn A. Cunningham, Carlos M. Villalón, Horst Vogel, Michael Camilleri, Carine Bécamel, Michael Gershon, Katharine Herrick-Davis, Trevor Sharp, Luc Maroteaux, Philippe Marin, Enza Lacivita, Bryan L. Roth, Stephanie W. Watts, Evelyn K. Lambe, Adam L. Halberstadt, Marcello Leopoldo, Daniel Hoyer, Anne Roumier, Milt Teitler, Severine Chaumont-Dubel, Gerard P. Ahern, Ruud Hovius, Adrian Newman-Tancredi, Gareth J. Sanger, Nathalie M. Goodfellow, Andrew C. McCreary, Giuseppe Di Giovanni, Sylvie Claeysen, John F. Neumaier, Finn Olav Levy, Nicholas M. Barnes, David Nelson, Kevin C. Fone, Joël Bockaert, Ghérici Hassaine, Rachel M. Hartley, Hugues Nury
Publikováno v:
Pharmacol Rev
Pharmacological Reviews
Pharmacological Reviews, American Society for Pharmacology and Experimental Therapeutics, 2020, 73 (1), pp.310-520. ⟨10.1124/pr.118.015552⟩
Pharmacological Reviews
Pharmacological Reviews, American Society for Pharmacology and Experimental Therapeutics, 2020, 73 (1), pp.310-520. ⟨10.1124/pr.118.015552⟩
5 HT receptors expressed throughout the human body are targets for established therapeutics and various drugs in development. Their diversity of structure and function reflects the important role 5-HT receptors play in physiologic and pathophysiologi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf55e4383f6dbf6d09b590b20342f025
https://pubmed.ncbi.nlm.nih.gov/33370241
https://pubmed.ncbi.nlm.nih.gov/33370241
Autor:
Paul A. Heppenstall, Satoko Takemoto, Miwa Umebayashi, Ruud Hovius, Annalisa Bucci, Mayya Sundukova, Kai Johnsson, Luc Reymond, Hideo Yokota, Howard Riezman
Functional membrane proteins in the plasma membrane are suggested to have specific membrane environments that play important roles to maintain and regulate the function of proteins. However, the local membrane environments of membrane proteins remain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f9019f29e83c534bf07fe5f9e326c840
https://doi.org/10.1101/2020.12.23.424145
https://doi.org/10.1101/2020.12.23.424145
Autor:
Jelmi uit de Bos, Daria Maslennikova, Ulrike Kutay, Renard Tm Lewis, Beat Fierz, Ruud Hovius, Rosemarie Ungricht, Naemi Luithle
Publikováno v:
eLife, 9
eLife
eLife, Vol 9 (2020)
eLife
eLife, Vol 9 (2020)
The inner nuclear membrane is functionalized by diverse transmembrane proteins that associate with nuclear lamins and/or chromatin. When cells enter mitosis, membrane-chromatin contacts must be broken to allow for proper chromosome segregation; yet h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f592d046467d85877e6cb7e7dcb71a3
https://hdl.handle.net/20.500.11850/461818
https://hdl.handle.net/20.500.11850/461818
Autor:
Ganesh R, Pathare, Alexiane, Decout, Selene, Glück, Simone, Cavadini, Kristina, Makasheva, Ruud, Hovius, Georg, Kempf, Joscha, Weiss, Zuzanna, Kozicka, Baptiste, Guey, Pauline, Melenec, Beat, Fierz, Nicolas H, Thomä, Andrea, Ablasser
Publikováno v:
Nature. 587(7835)
The DNA sensor cyclic GMP-AMP synthase (cGAS) initiates innate immune responses following microbial infection, cellular stress and cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c62a78936391fb06069061638e27bec5
https://pubmed.ncbi.nlm.nih.gov/32911482
https://pubmed.ncbi.nlm.nih.gov/32911482
Autor:
Thomas Vorherr, Rudolf Griss, Kui-Thong Tan, Pier Luca D’Alessandro, Ruud Hovius, Kai Johnsson, Silvia Scarabelli
Publikováno v:
Journal of the American Chemical Society
We are introducing a new approach to evaluate cellular uptake of drugs and drug candidates into living cells. The approach is based on converting the protein target of a given class of compounds into a fluorescent biosensor. By measuring the binding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8fa21b86bdc966ab1f3c18fed27a34c
https://doi.org/10.1021/acssensors.7b00331
https://doi.org/10.1021/acssensors.7b00331
Autor:
Sevil Zencir, Anne-Marinette Cao, Ruud Hovius, Beat Fierz, David Shore, Christoph F. Kurat, Anna Maria Stachowicz, Maxime Mivelaz, Slawomir Kubik, Iuliia Boichenko
Pioneer transcription factors (pTFs) bind to target sites within compact chromatin initiating chromatin remodeling and controlling the recruitment of downstream factors. The mechanisms by which pTFs overcome the chromatin barrier are not well underst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7adc84c11d74b77c418b2b5e6128626
Autor:
Miwa Umebayashi, Paul A. Heppenstall, Ruud Hovius, Mayya Sundukova, Kseniia Kirillova, Howard Riezman, Kai Johnsson, Joana Serrao, Luc Reymond, Efthymia Prifti, Annalisa Bucci
Optical monitoring of neuronal voltage using fluorescent indicators is a powerful approach for interrogation of the cellular and molecular logic of the nervous system. Here we describe a Semisynthetic Tethered Voltage Indicator (STeVI1) based upon Ni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24f9f418d17e4e4ab416eabb49e08fb1