Zobrazeno 1 - 10 of 77 pro vyhledávání: '"Rutteman Gerard R"'
1
Akademický článek
Specific down-regulation of XIAP with RNA interference enhances the sensitivity of canine tumor cell-lines to TRAIL and doxorubicin
Autor: Rothuizen Jan, Rutteman Gerard R, Arends Brigitte, Jonkers Martijn DB, Spee Bart, Penning Louis C
Publikováno v: Molecular Cancer, Vol 5, Iss 1, p 34 (2006)
Abstract Background Apoptosis resistance occurs in various tumors. The anti-apoptotic XIAP protein is responsible for inhibiting apoptosis by reducing caspase-3 activation. Our aim is to evaluate whether RNA inhibition against XIAP increases the sens
Externí odkaz: https://doaj.org/article/26a8404a23094690b77acfef1fbe11aa
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3
Multi-omics approach identifies germline regulatory variants associated with hematopoietic malignancies in retriever dog breeds
Autor: Evans, Jacquelyn M, Parker, Heidi G, Rutteman, Gerard R, Plassais, Jocelyn, Grinwis, Guy C M, Harris, Alexander C, Lana, Susan E, Ostrander, Elaine A, Sub Oncologie/Cytologie, VPDC pathologie, dPB CR, Veterinair Pathologisch Diagnostisch Cnt, LS Pathologie, VP pathologie
Publikováno v: PLoS Genetics, Vol 17, Iss 5, p e1009543 (2021)
PLoS Genetics
PLoS Genetics, 17(5). Public Library of Science
Histiocytic sarcoma is an aggressive hematopoietic malignancy of mature tissue histiocytes with a poorly understood etiology in humans. A histologically and clinically similar counterpart affects flat-coated retrievers (FCRs) at unusually high freque
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::358a4c16b40d652f90d634ee2cd90081
https://doi.org/10.1101/2021.04.05.438235
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4
Akademický článek
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6
Akademický článek
Nuclear DNA-Content in Mesenchymal Lesions in Dogs: Its Value as Marker of Malignancy and Extent of Genomic Instability.
Autor: Boerkamp, Kim M.1 K.M.Boerkamp@uu.nl, Rutteman, Gerard R.1 G.R.Rutteman@uu.nl, Kik, Marja J. L.2 M.Kik@uu.nl, Kirpensteijn, Jolle1 J.Kirpensteijn@uu.nl, Schulze, Christoph2 Christoph.Schulze@Landeslabor-bbb.de, Grinwis, Guy C. M.2 Grinwis@uu.nl
Publikováno v: Cancers. Dec2012, Vol. 4 Issue 4, p1300-1317. 18p. 5 Charts, 2 Graphs.
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7
Unclassified sarcomas: a study to improve classification in a cohort of Golden Retriever dogs
Autor: Boerkamp, Kim M, Hellmén, Eva, Willén, Helena, Grinwis, Guy C M, Teske, Erik, Rutteman, Gerard R, dCSCA AVR, dPB CR, Applied Veterinary Research, Sub Oncologie/Cytologie, Veterinair Pathologisch Diagnostisch Cnt, Dep Pathobiologie, dCSCA RMSC-2
Publikováno v: Journal of Veterinary Diagnostic Investigation, 28(6), 623. American Association of Veterinary Laboratory Diagnosticians
Morphologically, canine soft-tissue sarcomas (STSs) resemble human STSs. In humans, proper classification of STSs is considered essential to improve insight in the biology of these tumors, and to optimize diagnosis and therapy. To date, there is a pa
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ce1908ba4d9bef03cfb314878322ec6
https://dspace.library.uu.nl/handle/1874/345985
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8
Hypoxia Up-Regulates Galectin-3 in Mammary Tumor Progression and Metastasis
Autor: de Oliveira, Joana T, Ribeiro, Cláudia, Barros, Rita, Gomes, Catarina, de Matos, Augusto J, Reis, Celso A, Rutteman, Gerard R, Gärtner, Fátima, Sub Oncologie/Cytologie, CSCA TR2, Regenerative Medicine, Stem Cells & Cancer
Publikováno v: PLoS One, 10(7). Public Library of Science
PLoS ONE
PLoS ONE, Vol 10, Iss 7, p e0134458 (2015)
The tumor microenvironment encompasses several stressful conditions for cancer cells such as hypoxia, oxidative stress and pH alterations. Galectin-3, a well-studied member of the beta-galactoside-binding animal family of lectins has been implicated
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb96d062241c49777d17caba6b7da195
https://dspace.library.uu.nl/handle/1874/335480
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9
The two main forms of histiocytic sarcoma in the predisposed Flatcoated retriever dog display variation in gene expression
Autor: Boerkamp, Kim M, van Steenbeek, Frank G, Penning, Louis C, Groot Koerkamp, Marian J A, van Leenen, Dik, Vos-Loohuis, Manon, Grinwis, Guy C M, Rutteman, Gerard R, Tissue Repair, Sub Oncologie/Cytologie, CSCA AVM, Onderzoek, Universitair Veterinair Diagnostisch Lab, CSCA TR1, Biochemisch laboratorium, Veterinair Pathologisch Diagnostisch Cnt, PB AVM, Dep Pathobiologie, CSCA TR2
Publikováno v: PLoS ONE, Vol 9, Iss 6, p e98258 (2014)
PLoS ONE
PLoS One, 9(6). Public Library of Science
Examination of gene functions in specific tumor types improves insight in tumorigenesis and helps design better treatments. Due to the rarity of histiocytic/dendritic cell sarcoma in humans, it is difficult to accrue such knowledge. Therefore, compar
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8104991c269879ce28b8bbb7a253e0a1
http://europepmc.org/articles/PMC4041757?pdf=render
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10
Akademický článek
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