Untargeted metabolomics and infrared ion spectroscopy identify biomarkers for pyridoxine-dependent epilepsy.

Autor: Engelke UF; Translational Metabolic Laboratory, Department of Laboratory Medicine, Radboud University Medical Center, Nijmegen, Netherlands., van Outersterp RE; Institute for Molecules and Materials, FELIX Laboratory and., Merx J; Institute for Molecules and Materials, Synthetic Organic Chemistry, Radboud University, Nijmegen, Netherlands., van Geenen FA; Institute for Molecules and Materials, FELIX Laboratory and., van Rooij A; Translational Metabolic Laboratory, Department of Laboratory Medicine, Radboud University Medical Center, Nijmegen, Netherlands., Berden G; Institute for Molecules and Materials, FELIX Laboratory and., Huigen MC; Translational Metabolic Laboratory, Department of Laboratory Medicine, Radboud University Medical Center, Nijmegen, Netherlands., Kluijtmans LA; Translational Metabolic Laboratory, Department of Laboratory Medicine, Radboud University Medical Center, Nijmegen, Netherlands., Peters TM; Translational Metabolic Laboratory, Department of Laboratory Medicine, Radboud University Medical Center, Nijmegen, Netherlands.; Department of Neurology, Donders Institute for Brain, Cognition and Behavior, Radboud University Medical Center, Nijmegen, Netherlands., Al-Shekaili HH; Centre for Molecular Medicine and Therapeutics, British Columbia Children's Hospital Research Institute, Department of Medical Genetics, University of British Columbia Vancouver, British Columbia, Canada., Leavitt BR; Centre for Molecular Medicine and Therapeutics, British Columbia Children's Hospital Research Institute, Department of Medical Genetics, University of British Columbia Vancouver, British Columbia, Canada., de Vrieze E; Department of Otorhinolaryngology, Donders Institute for Brain, Cognition and Behavior, Radboud University Medical Center, Nijmegen, Netherlands., Broekman S; Department of Otorhinolaryngology, Donders Institute for Brain, Cognition and Behavior, Radboud University Medical Center, Nijmegen, Netherlands., van Wijk E; Department of Otorhinolaryngology, Donders Institute for Brain, Cognition and Behavior, Radboud University Medical Center, Nijmegen, Netherlands., Tseng LA; Department of Pediatrics, Emma Children's Hospital, Amsterdam University Medical Centers, Amsterdam, Netherlands., Kulkarni P; Translational Metabolic Laboratory, Department of Laboratory Medicine, Radboud University Medical Center, Nijmegen, Netherlands., Rutjes FP; Institute for Molecules and Materials, Synthetic Organic Chemistry, Radboud University, Nijmegen, Netherlands., Mecinović J; Institute for Molecules and Materials, Synthetic Organic Chemistry, Radboud University, Nijmegen, Netherlands.; Department of Physics, Chemistry and Pharmacy, University of Southern Denmark, Odense, Denmark., Struys EA; Department of Clinical Chemistry, Amsterdam University Medical Centers, location VU Medical Centre, Amsterdam, Netherlands., Jansen LA; Division of Pediatric Neurology, Washington University School of Medicine, St. Louis, Missouri, USA., Gospe SM Jr; Departments of Neurology and Pediatrics, University of Washington, Seattle, Washington, USA.; Department of Pediatrics, Duke University, Durham, North Carolina, USA., Mercimek-Andrews S; Division of Clinical and Metabolic Genetics, Department of Pediatrics, University of Toronto, Toronto, Ontario, Canada.; Department of Medical Genetics, University of Alberta, Edmonton, Alberta, Canada., Hyland K; Medical Neurogenetics Laboratories, Atlanta, Georgia, USA., Willemsen MA; Department of Pediatric Neurology, Radboud University Medical Centre, Nijmegen, Netherlands., Bok LA; Department of Pediatrics, Máxima Medical Centre, Veldhoven, Netherlands., van Karnebeek CD; Department of Pediatrics, Emma Children's Hospital, Amsterdam University Medical Centers, Amsterdam, Netherlands.; Department of Pediatrics-Metabolic Diseases, Radboud Center for Mitochondrial Medicine, Radboud University Medical Center, Nijmegen, Netherlands.; United for Metabolic Diseases (UMD), Netherlands., Wevers RA; Translational Metabolic Laboratory, Department of Laboratory Medicine, Radboud University Medical Center, Nijmegen, Netherlands., Boltje TJ; Institute for Molecules and Materials, Synthetic Organic Chemistry, Radboud University, Nijmegen, Netherlands., Oomens J; Institute for Molecules and Materials, FELIX Laboratory and.; Van't Hoff Institute for Molecular Sciences, University of Amsterdam, Amsterdam, Netherlands., Martens J; Institute for Molecules and Materials, FELIX Laboratory and., Coene KL; Translational Metabolic Laboratory, Department of Laboratory Medicine, Radboud University Medical Center, Nijmegen, Netherlands.

Publikováno v: The Journal of clinical investigation [J Clin Invest] 2021 Aug 02; Vol. 131 (15).

Trans-cyclooctene—a Swiss army knife for bioorthogonal chemistry: exploring the synthesis, reactivity, and applications in biomedical breakthroughs.

Autor: Adhikari, Karuna^1,2 (AUTHOR), Vanermen, Maarten^1,2 (AUTHOR), Da Silva, Gustavo² (AUTHOR), Van den Wyngaert, Tim^2,3 (AUTHOR), Augustyns, Koen¹ (AUTHOR) Koen.Augustyns@uantwerpen.be, Elvas, Filipe^2,3 (AUTHOR) Filipe.Elvas@uantwerpen.be

Publikováno v: EJNMMI Radiopharmacy & Chemistry. 6/6/2024, Vol. 9 Issue 1, p1-56. 56p.

Magnetic resonance imaging with upconversion nanoprobes capable of crossing the blood-cerebrospinal fluid barrier.

Autor: Han, Fang¹ (AUTHOR), Gao, Jiahao¹ (AUTHOR), Lv, Guanglei² (AUTHOR), Liu, Tao³ (AUTHOR), Hu, Qingfeng⁴ (AUTHOR), Zhu, Meilin¹ (AUTHOR), Du, Zunguo⁵ (AUTHOR), Yang, Jing¹ (AUTHOR), Yao, Zhenwei¹ (AUTHOR), Fang, Xiangming⁶ (AUTHOR) xiangming_fang@njmu.edu.cn, Ni, Dalong⁷ (AUTHOR) ndl12353@rjh.com.cn, Zhang, Jiawen¹ (AUTHOR) jiawen_zhang@fudan.edu.cn

Publikováno v: Journal of Nanobiotechnology. 1/30/2024, Vol. 22 Issue 1, p1-11. 11p.

Speeding up Viedma ripening.

Autor: Engwerda AH; Institute for Molecules and Materials, Radboud University, Heyendaalseweg 135, 6525 AJ, Nijmegen, The Netherlands. H.Meekes@science.ru.nl., Meekes H; Institute for Molecules and Materials, Radboud University, Heyendaalseweg 135, 6525 AJ, Nijmegen, The Netherlands. H.Meekes@science.ru.nl., Kaptein B; DSM Ahead R&D - Innovative Synthesis, PO Box 1066, 6160 BB Geleen, The Netherlands. bernard.kaptein@dsm.com., Rutjes FP; Institute for Molecules and Materials, Radboud University, Heyendaalseweg 135, 6525 AJ, Nijmegen, The Netherlands. H.Meekes@science.ru.nl., Vlieg E; Institute for Molecules and Materials, Radboud University, Heyendaalseweg 135, 6525 AJ, Nijmegen, The Netherlands. H.Meekes@science.ru.nl.

Publikováno v: Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2016 Oct 04; Vol. 52 (81), pp. 12048-12051.

A New Ir-NHC Catalyst for Signal Amplification by Reversible Exchange in D2 O.

Autor: Spannring P; Institute for Molecules and Materials, Radboud University, Heyendaalseweg 135, 6525 AJ Nijmegen, The Netherlands., Reile I; Institute for Molecules and Materials, Radboud University, Heyendaalseweg 135, 6525 AJ Nijmegen, The Netherlands., Emondts M; RWTH Aachen, Institut für Technische und Makromolekulare Chemie, Worringerweg 2, 52074 Aachen, Germany., Schleker PP; RWTH Aachen, Institut für Technische und Makromolekulare Chemie, Worringerweg 2, 52074 Aachen, Germany., Hermkens NK; Institute for Molecules and Materials, Radboud University, Heyendaalseweg 135, 6525 AJ Nijmegen, The Netherlands., van der Zwaluw NG; Institute for Molecules and Materials, Radboud University, Heyendaalseweg 135, 6525 AJ Nijmegen, The Netherlands., van Weerdenburg BJ; Institute for Molecules and Materials, Radboud University, Heyendaalseweg 135, 6525 AJ Nijmegen, The Netherlands., Tinnemans P; Institute for Molecules and Materials, Radboud University, Heyendaalseweg 135, 6525 AJ Nijmegen, The Netherlands., Tessari M; Institute for Molecules and Materials, Radboud University, Heyendaalseweg 135, 6525 AJ Nijmegen, The Netherlands., Blümich B; RWTH Aachen, Institut für Technische und Makromolekulare Chemie, Worringerweg 2, 52074 Aachen, Germany., Rutjes FP; Institute for Molecules and Materials, Radboud University, Heyendaalseweg 135, 6525 AJ Nijmegen, The Netherlands., Feiters MC; Institute for Molecules and Materials, Radboud University, Heyendaalseweg 135, 6525 AJ Nijmegen, The Netherlands. m.feiters@science.ru.nl.

Publikováno v: Chemistry (Weinheim an der Bergstrasse, Germany) [Chemistry] 2016 Jun 27; Vol. 22 (27), pp. 9277-82. Date of Electronic Publication: 2016 Jun 03.