Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Ruthie Davi"'
Publikováno v:
Nature reviews. Drug discovery. 19(12)
Randomized controlled trials are the accepted standard for evaluating investigational therapies, but such trials are sometimes not an option for reasons of ethics or feasibility. Here, we discuss opportunities to address evidence gaps by using histor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c113e610e3db3510ab1d1764fb602abc
https://pubmed.ncbi.nlm.nih.gov/32811986
https://pubmed.ncbi.nlm.nih.gov/32811986
Publikováno v:
Journal of Clinical Oncology. 38:e20521-e20521
e20521 Background: The randomized clinical trial (RCT) is the gold standard in drug development. However, for indications where patients have a strong preference for the investigational product, such as many oncology and rare diseases, the use of a S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9203bdf032637b8ba984892fd4c68f5b
https://doi.org/10.1200/jco.2020.38.15_suppl.e20521
https://doi.org/10.1200/jco.2020.38.15_suppl.e20521
Autor:
Lin-Chi Chen, David S. Lee, Somnath Sarkar, Steven Blotner, Michael Elashoff, Mark Chandler, Ruthie Davi, Donald A. Berry, Philip Beineke
Publikováno v:
Journal of Clinical Oncology. 35:7021-7021
7021 Background: Clinical trials of experimental drugs require controls. Concurrently randomized controls are the gold standard for judging drug effect. Historical controls are not ideal but are much more efficient and economical. Historical controls
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fb744455ce485b9c5503d6d5639a31a1
https://doi.org/10.1200/jco.2017.35.15_suppl.7021
https://doi.org/10.1200/jco.2017.35.15_suppl.7021