Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Ruthger van Roey"'
Autor:
Luís Almeida, Ruthger van Roey, Thiago Andrade Patente, Frank Otto, Tom Veldhuizen, Mohan Ghorasaini, Angela van Diepen, Gabriele Schramm, Jianyang Liu, Helena Idborg, Marina Korotkova, Per-Johan Jakobsson, Martin Giera, Cornelis Hendrik Hokke, Bart Everts
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
The parasitic helminth Schistosoma mansoni is a potent inducer of type 2 immune responses by stimulating dendritic cells (DCs) to prime T helper 2 (Th2) responses. We previously found that S. mansoni soluble egg antigens (SEA) promote the synthesis o
Externí odkaz:
https://doaj.org/article/81da8022d2aa40008df4aeac71952bd4
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Pancreatic cancer is a very aggressive disease with 5-year survival rates of less than 10%. The constantly increasing incidence and stagnant patient outcomes despite changes in treatment regimens emphasize the requirement of a better understanding of
Externí odkaz:
https://doaj.org/article/ee2c60151b584f50933fbe927f90219c
Autor:
Luuk de Haan, Johnny Suijker, Ruthger van Roey, Nina Berges, Elissaveta Petrova, Karla Queiroz, Wouter Strijker, Thomas Olivier, Oliver Poeschke, Sakshi Garg, Lenie J. van den Broek
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 15, p 8234 (2021)
The recruitment of T cells is a crucial component in the inflammatory cascade of the body. The process involves the transport of T cells through the vascular system and their stable arrest to vessel walls at the site of inflammation, followed by extr
Externí odkaz:
https://doaj.org/article/e18822e027634a1a969a3ade896b9357
Autor:
Harald Schuhwerk, Constantin Menche, Isabell Armstark, Pooja Gupta, Kathrin Fuchs, Ruthger van Roey, Mohammed H. Mosa, Carol I. Geppert, Stefanie Bärthel, Dieter Saur, Florian R. Greten, Simone Brabletz, Thomas Brabletz, Henner F. Farin, Marc P. Stemmler
The EMT-transcription factor ZEB1 is heterogeneously expressed in tumor cells and in cancer-associated fibroblasts (CAFs) in colorectal cancer (CRC). While ZEB1 in tumor cells regulates metastasis and therapy resistance, its role in CAFs is largely u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::17e29e3e113d6d88894ee754c11b9d04
https://doi.org/10.1101/2023.03.28.534565
https://doi.org/10.1101/2023.03.28.534565
Autor:
Harald Schuhwerk, Julia Kleemann, Pooja Gupta, Ruthger van Roey, Isabell Armstark, Martina Kreileder, Nora Feldker, Vignesh Ramesh, Yussuf Hajjaj, Kathrin Fuchs, Mousumi Mahapatro, Mojca Hribersek, Marco Volante, Arwin Groenewoud, Felix B. Engel, Paolo Ceppi, Markus Eckstein, Arndt Hartmann, Fabian Müller, Torsten Kroll, Marc P. Stemmler, Simone Brabletz, Thomas Brabletz
The DNA damage response (DDR) and epithelial-to-mesenchymal transition (EMT) are two crucial cellular programs in cancer biology. While the DDR orchestrates cell cycle progression, DNA repair and cell death, EMT promotes invasiveness, cellular plasti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eab6567ef70b9ff3ebe73befbe61449f
Publikováno v:
Frontiers in Cell and Developmental Biology
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Pancreatic cancer is a very aggressive disease with 5-year survival rates of less than 10%. The constantly increasing incidence and stagnant patient outcomes despite changes in treatment regimens emphasize the requirement of a better understanding of
Autor:
Karla Queiroz, Elissaveta Petrova, Johnny Suijker, Ruthger van Roey, Nina Berges, Lenie J. van den Broek, Luuk de Haan, Sakshi Garg, Thomas Olivier, Oliver Poeschke, Wouter Strijker
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 8234, p 8234 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 15
International Journal of Molecular Sciences
Volume 22
Issue 15
The recruitment of T cells is a crucial component in the inflammatory cascade of the body. The process involves the transport of T cells through the vascular system and their stable arrest to vessel walls at the site of inflammation, followed by extr
Autor:
Kathrin Fuchs, Fabian Müller, Geert Berx, Julia Kleemann, Isabell Frisch, Rebecca L Eccles, Marc P. Stemmler, Thomas Brabletz, Daniel Baumhoer, Harald Schuhwerk, Maike Roas, Ruthger van Roey, Simone Brabletz, Abbas Agaimy, Manuel Ruh
Publikováno v:
JOURNAL OF PATHOLOGY
Osteosarcoma is an often‐fatal mesenchyme‐derived malignancy in children and young adults. Overexpression of EMT‐transcription factors (EMT‐TFs) has been associated with poor clinical outcome. Here, we demonstrated that the EMT‐TF ZEB1 is a