Zobrazeno 1 - 9 of 9 pro vyhledávání: '"Ruth Verplaetse"'
1
Hematocrit-Independent Quantitation of Stimulants in Dried Blood Spots: Pipet versus Microfluidic-Based Volumetric Sampling Coupled with Automated Flow-Through Desorption and Online Solid Phase Extraction-LC-MS/MS Bioanalysis
Autor: Jack Henion, Ruth Verplaetse
Publikováno v: Analytical Chemistry. 88:6789-6796
A workflow overcoming microsample collection issues and hematocrit (HCT)-related bias would facilitate more widespread use of dried blood spots (DBS). This report describes comparative results between the use of a pipet and a microfluidic-based sampl
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf2c0698de98d5342714c7f5f02d585f
https://doi.org/10.1021/acs.analchem.6b01190
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2
Quantitative determination of opioids in whole blood using fully automated dried blood spot desorption coupled to on-line SPE-LC-MS/MS
Autor: Jack Henion, Ruth Verplaetse
Publikováno v: Drug Testing and Analysis. 8:30-38
Opioids are well known, widely used painkillers. Increased stability of opioids in the dried blood spot (DBS) matrix compared to blood/plasma has been described. Other benefits provided by DBS techniques include point-of-care collection, less invasiv
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f001d5353b21744e64cc60878fa11d05
https://doi.org/10.1002/dta.1927
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3
Development and validation of a new TD-GC/MS method and its applicability in the search for human and animal decomposition products
Autor: W. Van de Voorde, Jan Tytgat, D. Maes, E. Rosier, Wim Develter, Ruth Verplaetse, M. Dekens, Eva Cuypers
Publikováno v: Analytical and Bioanalytical Chemistry
Differentiation between human and animal remains by means of analysis of volatile compounds released during decomposition is impossible since no volatile marker(s) specific for human decomposition has been established today. Hence, the identification
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6256efa4369770590303a6b429e99e5
http://europepmc.org/articles/PMC4026628
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4
Quantitative determination of opioids in whole blood using fully automated dried blood spot desorption coupled to on-line SPE-LC-MS/MS
Autor: Ruth, Verplaetse, Jack, Henion
Publikováno v: Drug testing and analysis. 8(1)
Opioids are well known, widely used painkillers. Increased stability of opioids in the dried blood spot (DBS) matrix compared to blood/plasma has been described. Other benefits provided by DBS techniques include point-of-care collection, less invasiv
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ea4ed6af5ca78dbe68de266236be72d1
https://pubmed.ncbi.nlm.nih.gov/26607771
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5
Chronic administration of anticholinergics in rats induces a shift from muscarinic to purinergic transmission in the bladder wall
Autor: Thomas Gevaert, Silvia Pinto, Mathieu Boudes, Jan Tytgat, Dirk De Ridder, Thomas Voets, Jan Franken, Aurélie Menigoz, Rudi Vennekens, Ruth Verplaetse, Pieter Uvin
Publikováno v: European urology. 64(3)
Background First-line pharmacotherapy for overactive bladder consists of anticholinergics. However, patient compliance is exceptionally low, which may be due to progressive loss of effectiveness. Objective To decipher the involved molecular mechanism
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75554604ad3fb737bd112b9e42170547
https://pubmed.ncbi.nlm.nih.gov/25986845
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6
Screening of Urine and Blood Using Limited Sample Preparation and Information Dependent Acquisition with LC-MS/MS as Alternative for Immunoassays in Forensic Toxicology
Autor: Eva Cuypers, Jan Tytgat, Ruth Verplaetse, Sylvie Decabooter
Publikováno v: Journal of Forensic Toxicology & Pharmacology.
Screening of Urine and Blood Using Limited Sample Preparation and Information Dependent Acquisition with LC-MS/MS as Alternative for Immunoassays in Forensic Toxicology Immunoassays are widely used to perform an initial toxicological screening of bio
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::113b4d0228db0b327a6642d1ce77837e
https://doi.org/10.4172/2325-9841.1000112
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7
The evaluation of the applicability of a high pH mobile phase in ultrahigh performance liquid chromatography tandem mass spectrometry analysis of benzodiazepines and benzodiazepine-like hypnotics in urine and blood
Autor: Jan Tytgat, Eva Cuypers, Ruth Verplaetse
Publikováno v: Journal of chromatography. A. 1249
A sensitive liquid chromatography tandem mass spectrometry method was developed and validated for simultaneous detection of benzodiazepines, benzodiazepine-like hypnotics and some metabolites (7-aminoflunitrazepam, alprazolam, bromazepam, brotizolam,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5d89f5a5e4d8066497d3cbe92391899
https://pubmed.ncbi.nlm.nih.gov/22749457
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8
Development and validation of a sensitive ultra performance liquid chromatography tandem mass spectrometry method for the analysis of fentanyl and its major metabolite norfentanyl in urine and whole blood in forensic context
Autor: Ruth Verplaetse, Jan Tytgat
Publikováno v: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 878(22)
Fentanyl and its major metabolite norfentanyl often occur in low doses in biological samples. Therefore, a highly sensitive liquid chromatography tandem mass spectrometry (LC–MS/MS) method has been developed and fully validated. Sample preparation
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11d14b0b9dc47ae011ee1cddad87e27f
https://pubmed.ncbi.nlm.nih.gov/20542478
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