Výsledky vyhledávání - "Ruth V Bushnell"

Akademický článek

A novel gamma radiation-inactivated sabin-based polio vaccine.

Autor: Gregory J Tobin, John K Tobin, Elena K Gaidamakova, Taralyn J Wiggins, Ruth V Bushnell, Wai-Ming Lee, Vera Y Matrosova, Stephen J Dollery, Heather N Meeks, Diana Kouiavskaia, Konstantin Chumakov, Michael J Daly

Publikováno v: PLoS ONE, Vol 15, Iss 1, p e0228006 (2020)

A concerted action on the part of international agencies and national governments has resulted in the near-eradication of poliomyelitis. However, both the oral polio vaccine (OPV) and the inactivated polio vaccine (IPV) have deficiencies which make t

Externí odkaz: https://doaj.org/article/7c240a32ddfd483197be6de198ecd437

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Akademický článek

A highly immunogenic UVC inactivated Sabin based polio vaccine

Autor: Gregory J. Tobin, John K. Tobin, Taralyn J. Wiggins, Ruth V. Bushnell, Arina V. Kozar, Matthew F. Maale, David A. MacLeod, Heather N. Meeks, Michael J. Daly, Stephen J. Dollery

Publikováno v: npj Vaccines, Vol 9, Iss 1, Pp 1-8 (2024)

Abstract Despite their efficacy, the currently available polio vaccines, oral polio vaccine (OPV) and inactivated polio vaccine (IPV), possess inherent flaws posing significant challenges in the global eradication of polio. OPV, which uses live Sabin

Externí odkaz: https://doaj.org/article/82ec371184844129a6db076380e478d0

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Akademický článek

Evolution of H3N2 influenza virus in a guinea pig model.

Autor: Jinxue Long, Ruth V Bushnell, John K Tobin, Keyao Pan, Michael W Deem, Peter L Nara, Gregory J Tobin

Publikováno v: PLoS ONE, Vol 6, Iss 7, p e20130 (2011)

Studies of influenza virus evolution under controlled experimental conditions can provide a better understanding of the consequences of evolutionary processes with and without immunological pressure. Characterization of evolved strains assists in the

Externí odkaz: https://doaj.org/article/a484905c7679431ba6ddab1a3b29981d

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Akademický článek

Select Whole-Cell Biofilm-Based Immunogens Protect against a Virulent Staphylococcus Isolate in a Stringent Implant Model of Infection

Autor: Stephen J. Dollery, Janette M. Harro, Taralyn J. Wiggins, Brendan P. Wille, Peter C. Kim, John K. Tobin, Ruth V. Bushnell, Naomi J. P. E. R. Tasker, David A. MacLeod, Gregory J. Tobin

Publikováno v: Vaccines, Vol 10, Iss 6, p 833 (2022)

Many microbes of concern to human health remain without vaccines. We have developed a whole-microbe inactivation technology that enables us to rapidly inactivate large quantities of a pathogen while retaining epitopes that were destroyed by previous

Externí odkaz: https://doaj.org/article/a10dfb6456f24fdfb13f1dc0daf63ee1

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Akademický článek

Radiation-Inactivated Acinetobacter baumannii Vaccine Candidates

Autor: Stephen J. Dollery, Daniel V. Zurawski, Elena K. Gaidamakova, Vera Y. Matrosova, John K. Tobin, Taralyn J. Wiggins, Ruth V. Bushnell, David A. MacLeod, Yonas A. Alamneh, Rania Abu-Taleb, Mariel G. Escatte, Heather N. Meeks, Michael J. Daly, Gregory J. Tobin

Publikováno v: Vaccines, Vol 9, Iss 2, p 96 (2021)

Acinetobacter baumannii is a bacterial pathogen that is often multidrug-resistant (MDR) and causes a range of life-threatening illnesses, including pneumonia, septicemia, and wound infections. Some antibiotic treatments can reduce mortality if dosed

Externí odkaz: https://doaj.org/article/975d9d8c0a5940009a01e2707c28e8ae

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Whole-cell vaccine candidates induce a protective response against virulent Acinetobacter baumannii

Autor: Stephen J. Dollery, Daniel V. Zurawski, Ruth V. Bushnell, John K. Tobin, Taralyn J. Wiggins, David A. MacLeod, Naomi J. P. E. R. Tasker, Yonas A. Alamneh, Rania Abu-Taleb, Christine M. Czintos, Wanwen Su, Mariel G. Escatte, Heather N. Meeks, Michael J. Daly, Gregory J. Tobin

Publikováno v: Frontiers in Immunology. 13

Acinetobacter baumannii causes multi-system diseases in both nosocomial settings and a pre-disposed general population. The bacterium is not only desiccation-resistant but also notoriously resistant to multiple antibiotics and drugs of last resort in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ae5cf266926ec84d88ef92b3d702aea2
https://doi.org/10.3389/fimmu.2022.941010

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Computer vision enabled funnel adapted sensing tube (FAST) for power-free and pipette-free nucleic acid detection

Autor: Mengdi Bao, Shuhuan Zhang, Chad ten Pas, Stephen J. Dollery, Ruth V. Bushnell, F. N. U. Yuqing, Rui Liu, Guoyu Lu, Gregory J. Tobin, Ke Du

Publikováno v: Lab on a chip. 22(24)

A simple, portable, and low-cost microfluidic system-funnel adapted sensing tube (FAST) is developed as an integrated, power-free, and pipette-free biosensor for viral nucleic acids. This FAST chip consists of four reaction chambers separated by carb

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::683b2dcc00dfe44007d5e5bb98fb873c
https://pubmed.ncbi.nlm.nih.gov/36111877

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