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pro vyhledávání: '"Ruth S. Phillips"'
Publikováno v:
Journal of Microbiology & Biology Education, Vol 21, Iss 3 (2020)
We designed a 16-week scaffolded student-scientist curriculum using inquiry-based research experiences integrated with professional development activities. This curriculum was implemented to teach undergraduate students enrolled in an introduction to
Externí odkaz:
https://doaj.org/article/cf37fed7ef424d14a698494cda923661
Publikováno v:
Journal of Microbiology & Biology Education
Journal of Microbiology & Biology Education, Vol 21, Iss 3 (2020)
Journal of Microbiology & Biology Education, Vol 21, Iss 3 (2020)
We designed a 16-week scaffolded student-scientist curriculum using inquiry-based research experiences integrated with professional development activities. This curriculum was implemented to teach undergraduate students enrolled in an introduction to
Autor:
Perry J. Blackshear, Sanjukta Ghosh, Eric K. Richfield, Wi S. Lai, Ruth S. Phillips, Silvia V.B. Ramos
Publikováno v:
Biology of Reproduction. 73:297-307
Members of the tristetraprolin (TTP) family of CCCH tandem zinc finger (TZF) proteins can bind directly to AU-rich elements (ARE) in mRNA, causing deadenylation and destabilization of the transcripts to which they bind. We describe here a novel fourt
Autor:
Erik N. Meyers, Perry J. Blackshear, Robert R. Maronpot, Trisha Castranio, Ruth S. Phillips, Noah A. Byrd, Sanjukta Ghosh, Yuji Mishina, Deborah J. Stumpo
Publikováno v:
Molecular and Cellular Biology. 24:6445-6455
The mouse gene Zfp36L1 encodes zinc finger protein 36-like 1 (Zfp36L1), a member of the tristetraprolin (TTP) family of tandem CCCH finger proteins. TTP can bind to AU-rich elements within the 3'-untranslated regions of the mRNAs encoding tumor necro
Publikováno v:
Journal of Biological Chemistry. 277:11606-11613
Members of the tristetraprolin (TTP) family of CCCH tandem zinc finger proteins can bind directly to certain types of AU-rich elements (AREs) in mRNA. Experiments in TTP-deficient mice have shown that TTP is involved in the physiological destabilizat
Autor:
Elizabeth A. Kennington, Ester Carballo, Wi S. Lai, Julie R. Strum, Perry J. Blackshear, Ruth S. Phillips
Publikováno v:
Molecular and Cellular Biology. 19:4311-4323
Mice deficient in tristetraprolin (TTP), the prototype of a family of CCCH zinc finger proteins, develop an inflammatory syndrome mediated by excess tumor necrosis factor alpha (TNF-alpha). Macrophages derived from these mice oversecrete TNF-alpha, b
Autor:
Maria M. Milla, Ruth S. Phillips, Jonathan M. Horowitz, Kathleen T. Rogers, Peter D.R. Higgins
Publikováno v:
Proceedings of the National Academy of Sciences. 93:7594-7599
E2F is a heterodimeric transcription factor that regulates the expression of genes at the G1/S boundary and is composed of two related but distinct families of proteins, E2F and DP. E2F/DP heterodimers form complexes with the retinoblastoma (Rb) prot
Publikováno v:
Zinc Finger Proteins ISBN: 9780306482298
A small family of mammalian zinc finger proteins containing an unusual putative tandem zinc finger motif was identified approximately 13 years ago. The tandem zinc finger domain was characterized by two hypothetical fingers with identical Cx8Cx5Cx3H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f15fdddbeaabeef3618ea2f5d4f570d3
https://doi.org/10.1007/0-387-27421-9_13
https://doi.org/10.1007/0-387-27421-9_13
Autor:
Cheryl B. Bock, Perry J. Blackshear, Fernando Ribeiro-Neto, Deborah J. Stumpo, Elizabeth A. Kennington, Silvia B. V. Ramos, Ruth S. Phillips
Publikováno v:
Development (Cambridge, England). 131(19)
The CCCH tandem zinc finger protein, Zfp36l2, like its better-known relative tristetraprolin (TTP), can decrease the stability of AU-rich element-containing transcripts in cell transfection studies; however, its physiological importance is unknown. W
Publikováno v:
Progress in nucleic acid research and molecular biology. 75
The three known mammalian CCCH tandem zinc finger proteins of the tristetraprolin (TTP) class have recently been demonstrated to be mRNA-binding proteins. The prototype, TTP, functions in normal physiology to promote the instability of the tumor necr