Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Ruth S. Mwatelah"'
Autor:
Aloysious Ssemaganda, Francois Cholette, Michelle Perner, Cheli Kambaran, Wendy Adhiambo, Peter M. Wambugu, Henok Gebrebrhan, Amy Lee, Faisal Nuhu, Ruth S. Mwatelah, Naima Jahan, Tosin E. Omole, Tabitha Wanjiru, Apollo Gitau, Joshua Kimani, Lyle R. McKinnon
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Regulatory T cells (Tregs) play important roles in tissue homeostasis, but few studies have investigated tissue Tregs in the context of genital inflammation, HIV target cell density, and vaginal microbiota in humans. In women from Nairobi (n=64), the
Externí odkaz:
https://doaj.org/article/494025d9bf704595991953ddaa50bf00
Autor:
Amy Lee, François Cholette, Apollo Gitau, Joshua Kimani, Lyle R. McKinnon, Tabitha Wanjiru, Wendy Adhiambo, Henok Gebrebrhan, Faisal Nuhu, Tosin E. Omole, Naima Jahan, Ruth S. Mwatelah, Michelle Perner, Peter M. Wambugu, Aloysious Ssemaganda, Cheli Kambaran
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology
Frontiers in Immunology
Regulatory T cells (Tregs) play important roles in tissue homeostasis, but few studies have investigated tissue Tregs in the context of genital inflammation, HIV target cell density, and vaginal microbiota in humans. In women from Nairobi (n=64), the
Autor:
Ruth S Mwatelah, Raphael M Lwembe, Saida Osman, Bernhards R Ogutu, Rashid Aman, Rose C Kitawi, Laura N Wangai, Florence A Oloo, Gilbert O Kokwaro, Washingtone Ochieng
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0132287 (2015)
Injection drug use is steadily rising in Kenya. We assessed the prevalence of both human immunodeficiency virus type 1 (HIV-1) and hepatitis C virus (HCV) infections among injecting heroin users (IHUs) at the Kenyan Coast.A total of 186 IHUs (mean ag
Externí odkaz:
https://doaj.org/article/34e5d9da391441eab67c9c2cf1ea92cc
Autor:
Naomi Siele, Henok Gebrebrhan, Ruth S. Mwatelah, Sandra Choi, Paul Sandstrom, N. Vincent Reyes, Joshua Kimani, Lyle R. McKinnon, Irene Martin, Maureen Akolo, John E. Kim, François Cholette, Jie Li, T. Blake Ball, John L. Ho, Hezhao Ji, Peter M. Njogu, Cheli Kambaran, Robert Lorway, Wendy Adhiambo, Michael G. Becker, Supriya D. Mehta, Aida Sivro, Paul J. McLaren, Shelley W. Peterson
Publikováno v:
AIDS (London, England). 35(7)
Objective Both HIV infection and identifying as MSM have been linked to altered rectal microbiota composition, but few studies have studied sexual behavioural associations with rectal microbiota within MSM. In addition, most rectal microbiota studies
Autor:
Sharmistha Mishra, Nzioki King’ola, Lyle R. McKinnon, Alexander S. Zevin, Peter Gichangi, Sammy Wambua, Michael G. Becker, Aida Sivro, Cheli Kambaran, Nichole R. Klatt, Paul J. McLaren, Marissa Becker, Eve Cheuk, Huiting Ma, Henok Gebrebrhan, Ruth S. Mwatelah
Publikováno v:
Journal of acquired immune deficiency syndromes (1999). 85(1)
BACKGROUND Although nonoptimal vaginal bacteria and inflammation have been associated with increased HIV risk, the upstream drivers of these phenotypes are poorly defined in young African women. SETTING Mombasa, Kenya. METHODS We characterized vagina
Autor:
Quarraisha Abdool Karim, Salim S. Abdool Karim, Lyle R. McKinnon, Cheryl Baxter, Ruth S. Mwatelah
Publikováno v:
Journal of the International AIDS Society
Introduction Globally, sexually transmitted infections (STI) affect >300 million people annually, and are a major cause of sexual and reproductive health complications in women. In this commentary, we describe how STIs interact with the immune and no
Autor:
Shelley W. Peterson, Christine Bonner, Eve Cheuk, Irene Martin, Sharmistha Mishra, Grant McClarty, Peter Gichangi, Sammy Wambua, Faisal Nuhu, Marissa Becker, Tosin E. Omole, Nzioki King'ola, Lyle R. McKinnon, Naima Jahan, Ruth S. Mwatelah
Publikováno v:
Poster Presentations.
Background Bacterial STIs increase mucosal inflammation and HIV acquisition risk. However, most data are limited to symptomatic STIs, and more data are required regarding the prevalence and correlates of asymptomatic bacterial STIs among high-risk yo
Autor:
Nichole R. Klatt, Sammy Wambua, Huiting Ma, Paul J. McLaren, Marissa Becker, Peter Gichangi, Nzioki King’ola, Eve Cheuk, Ruth S. Mwatelah, Aida Sivro, Lyle R. McKinnon, Sharmistha Mishra, Cheli Kambaran, Alexander S. Zevin, Henok Gebrebrhan
Publikováno v:
SSRN Electronic Journal.
Background: Certain cervicovaginal microbiota and inflammatory cytokines are strongly associated with each other and with HIV acquisition, but the upstream drivers of this "risk milieu" remain partially defined. Methods: We characterized the vaginal
Autor:
Rupert Kaul, James Arthos, Aida Sivro, Lyle R. McKinnon, Lenine J. P. Liebenberg, Salim S. Abdool Karim, Natasha Samsunder, Anthony S. Fauci, Vineet Joag, Nigel Garrett, Aftab A. Ansari, Jintanat Ananworanich, Anisha Balgobin, AO Anzala, Alexandra Schuetz, Jo-Ann S. Passmore, Nittaya Phanuphak, Ruth S. Mwatelah, Quarraisha Abdool Karim, Nonhlanhla Yende-Zuma, Bernard S. Bagaya, Daniel J. Sheward, Rv study groups, Noah Kiwanuka, Joshua Kimani, Claudia Cicala, Sergey Yegorov, Andrew T. Stalker, Fatima Nawaz, Carolyn Williamson, Philippe Selhorst
Publikováno v:
Science Translational Medicine. 10
The gastrointestinal (GI) mucosa is central to HIV pathogenesis, and the integrin α4β7 promotes the homing of immune cells to this site, including those that serve as viral targets. Data from simian immunodeficiency virus (SIV) animal models sugges
Autor:
Mkaya Mwamburi, Nancy Lagat, Ruth S. Mwatelah, Raphael Lwembe, Dorothy J. Ochieng, Kevin Omondi Onyango, Maureen J. Kimulwo, Timothy J. Nzomo, Rashid Aman, Rose C. Kitawi, Bernhards Ogutu, Florence Oloo, Washingtone Ochieng, Joyceline Kinyua
Publikováno v:
JAIDS Journal of Acquired Immune Deficiency Syndromes. 69:e49-e56
BACKGROUND Universal access to highly active antiretroviral therapy (HAART) is still elusive in most developing nations. We asked whether peer support influenced adherence and treatment outcome and if a single viral load (VL) could define treatment f