Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Ruth Pofahl"'
Publikováno v:
Oncotarget
// Jayesh Deshmukh 1 , Ruth Pofahl 1 , Herbert Pfister 2 , Ingo Haase 1 1 Department of Dermatology, University of Cologne, Cologne, 50937, Germany 2 Institute of Virology, University of Cologne, Cologne, 50935, Germany Correspondence to: Jayesh Desh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2582792c1b2e3f632746e9d88c6521fa
https://doi.org/10.18632/oncotarget.11069
https://doi.org/10.18632/oncotarget.11069
Publikováno v:
Journal of Investigative Dermatology. 134(10):2541-2550
Strong inhibition of NF-κB signaling in the epidermis results in spontaneous skin inflammation in mice and men. As there is evidence for linkage between polymorphisms within the NF-κB signaling pathway and human inflammatory skin phenotypes, we ask
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a8fd920fff5ae69c4da769964330639
Autor:
Renate Knaup, Ruth Pofahl, Kristina Behrendt, Z Hao, Thomas Krieg, D Ussath, Ingo Haase, A Hedrych-Ozimina
Publikováno v:
Cell Death & Differentiation. 18:155-163
FAS/CD95/Apo-1 is a ubiquitously expressed cell-surface receptor involved in the initiation of programmed cell death. Its function in epidermal keratinocytes has been incompletely defined. Available evidence from in vitro studies points to important
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb2b1a2403f41a23dd647a3db3928415
https://doi.org/10.1038/cdd.2010.83
https://doi.org/10.1038/cdd.2010.83
Autor:
Anna Chrostek-Grashoff, Ruth Pofahl, Thomas Krieg, Helmut W. Klein, Benedikt Hartwig, Michael Tscharntke, Carien M. Niessen, Neil Smyth, Cord Brakebusch, Volker Herzog, Catherin Niemann, Ingo Haase
Publikováno v:
Journal of Cell Science. 120:1480-1490
To address the functions of Rac1 in keratinocytes of the basal epidermal layer and in the outer root sheath of hair follicles, we generated transgenic mice expressing a dominant inhibitory mutant of Rac, N17Rac1, under the control of the keratin 14 p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd8d0894756c10d7ef7d09ed1164f55c
https://doi.org/10.1242/jcs.03426
https://doi.org/10.1242/jcs.03426
Autor:
Renate Knaup, Thomas Krieg, Pierre Chambon, Doreen Markur, Daniel Metzger, Ruth Pofahl, Manolis Pasparakis, Athanasios Stratis, Ingo Haase
Publikováno v:
Journal of Investigative Dermatology
Journal of Investigative Dermatology, Nature Publishing Group, 2006, 126 (3), pp.614-20. ⟨10.1038/sj.jid.5700092⟩
Journal of Investigative Dermatology, Nature Publishing Group, 2006, 126 (3), pp.614-20. ⟨10.1038/sj.jid.5700092⟩
International audience; Skin inflammation is a complex process that involves interactions between various cell types residing in different skin compartments. Using mice with conditionally targeted I kappa B kinase 2 (IKK2) alleles, we have previously
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dce3e3268af785d507013e96da72530
https://doi.org/10.1038/sj.jid.5700092
https://doi.org/10.1038/sj.jid.5700092
Publikováno v:
Journal of Cell Science. 116:3227-3238
Adult epidermal keratinocytes migrate by crawling, a process that requires protrusion of the plasma membrane at the front of the cell and contraction of the cell body at the rear. We have found that epidermal growth factor (EGF)and insulin-like growt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dca568fc11619c4d6b1c24d097f3e64c
https://doi.org/10.1242/jcs.00610
https://doi.org/10.1242/jcs.00610
Publikováno v:
Cell Death & Disease
Non-melanoma skin cancer (NMSC) is the most common type of cancer. Increased expression and activity of Rac1, a small Rho GTPase, has been shown previously in NMSC and other human cancers; suggesting that Rac1 may function as an oncogene in skin. DMB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58e692457870b025cda2250847abbdb6
http://europepmc.org/articles/PMC5386559
http://europepmc.org/articles/PMC5386559
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 19(13)
Although it is known that growth factor signaling cascades are active during epithelial wound healing, signals that regulate reepithelialization after wounding are not very well characterized. The small GTP binding protein Ras is a molecular switch i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e31ed72b0c5a750c146973abbe9f5c39
https://pubmed.ncbi.nlm.nih.gov/16170018
https://pubmed.ncbi.nlm.nih.gov/16170018
Autor:
Neil Smyth, Ralf Paus, Jennifer E. Klatte, Ruth Pofahl, Michael Tscharntke, Cord Brakebusch, Carien M. Niessen, Catherin Niemann, Ingo Haase, Kristina Behrendt, Thomas Krieg, Wilhelm Bloch
Publikováno v:
Development. 139:e907-e907
The small GTPase Rac1 is ubiquitously expressed in proliferating and differentiating layers of the epidermis and hair follicles. Previously, Rac1 was shown to regulate stem cell behaviour in these compartments. We have asked whether Rac1 has, in addi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ee8f7f97bfad5bc688070f9c5472884
https://doi.org/10.1242/dev.082123
https://doi.org/10.1242/dev.082123