Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Ruth P. Cusack"'
Autor:
Christiane E. Whetstone, BSc, Ruth P. Cusack, MB, MPH, Emma Price, MSc, Karen Howie, Catie Stevens, BSc, Dhuha Al-Sajee, MD, PhD, Sue Beaudin, BSc, Jennifer Wattie, Nadia Alsaji, MBChB, Abbey Schlatman, BSc, Vanessa Luk, BHSc, Xiaotian Ju, PhD, Paul O’Byrne, MB, Mark Inman, MD, PhD, Roma Sehmi, PhD, Hermenio Lima, MD, PhD, Gail M. Gauvreau, PhD
Publikováno v:
Journal of Allergy and Clinical Immunology: Global, Vol 3, Iss 4, Pp 100310- (2024)
Background: Atopic dermatitis (AD) is a skin barrier dysfunction characterized by tissue eosinophilia. Objective: In patients with AD, we evaluated the effect of eosinophil depletion with benralizumab on markers of inflammation in skin after intrader
Externí odkaz:
https://doaj.org/article/6a842f379659480d957c7c5a1c8f6866
Publikováno v:
Therapeutic Advances in Respiratory Disease, Vol 16 (2022)
Externí odkaz:
https://doaj.org/article/6801d5800058415da6af4843de1b3157
Autor:
Mangalakumari Jeyanathan, Dominik K. Fritz, Sam Afkhami, Emilio Aguirre, Karen J. Howie, Anna Zganiacz, Anna Dvorkin-Gheva, Michael R. Thompson, Richard F. Silver, Ruth P. Cusack, Brian D. Lichty, Paul M. O’Byrne, Martin Kolb, Maria Fe C. Medina, Myrna B. Dolovich, Imran Satia, Gail M. Gauvreau, Zhou Xing, Fiona Smaill
Publikováno v:
JCI Insight, Vol 7, Iss 3 (2022)
Background Adenovirus-vectored (Ad-vectored) vaccines are typically administered via i.m. injection to humans and are incapable of inducing respiratory mucosal immunity. However, aerosol delivery of Ad-vectored vaccines remains poorly characterized,
Externí odkaz:
https://doaj.org/article/0f5b7f6ff7fa419a8108b00742172faf
Autor:
Imran Satia, Adil Adatia, Ruth P. Cusack, Justina M. Greene, Paul M. O'Byrne, Kieran J. Killian, Neil Johnston
Publikováno v:
ERJ Open Research, Vol 7, Iss 2 (2021)
Background The importance of age, sex and respiratory virus prevalence in emergency department (ED) visits and hospitalisations for respiratory tract infections (RTIs), asthma and COPD in a whole population over time is not well established. Methods
Externí odkaz:
https://doaj.org/article/c313c9440d874e299d0db8d9c4a0f84f
Publikováno v:
Cells, Vol 11, Iss 7, p 1105 (2022)
The airway epithelium is the first line of defense for the lungs, detecting inhaled environmental threats through pattern recognition receptors expressed transmembrane or intracellularly. Activation of pattern recognition receptors triggers the relea
Externí odkaz:
https://doaj.org/article/b52d4bd1256e48a591baddc884b0ef3b
Publikováno v:
Breathe, Vol 15, Iss 1, Pp e24-e35 (2019)
Globally, chronic obstructive pulmonary disease (COPD) is the fourth major cause of mortality and morbidity and projected to rise to third within a decade as our efforts to prevent, identify, diagnose and treat patients at a global population level h
Externí odkaz:
https://doaj.org/article/c1e3f9cf9ea7418b9edc467744f2192a
Publikováno v:
Cells, Vol 10, Iss 4, p 817 (2021)
Asthma is a complex and chronic inflammatory disease of the airways, characterized by variable and recurring symptoms, reversible airflow obstruction, bronchospasm, and airway eosinophilia. As the pathophysiology of asthma is becoming clearer, the id
Externí odkaz:
https://doaj.org/article/e62cb91a1dd14436b3f1af9ea099806e
Publikováno v:
Immunology and Allergy Clinics of North America. 43:169-185
Poorly controlled asthma can affect neonatal outcomes including congenital anomalies, which can be reduced with appropriate asthma care during pregnancy. Although there is a concern regarding the safety of asthma medication use during pregnancy and c
Autor:
Maral Ranjbar, Christiane E. Whetstone, Hafsa Omer, Lucy Power, Ruth P. Cusack, Gail M. Gauvreau
Publikováno v:
Genes. 13(10)
Asthma is a chronic disease of the airways characterized by inflammation, tightened muscles, and thickened airway walls leading to symptoms such as shortness of breath, chest tightness, and cough in patients. The increased risk of asthma in children
Autor:
Gail M. Gauvreau, Kieran J. Killian, Firoz Mian, John Bienenstock, Abbey Schlatman, Imran Satia, Jennifer Wattie, Ruth P. Cusack, Paul M. O'Byrne, Paul Forsythe, Catie Stevens
Publikováno v:
Clinical & Experimental Allergy. 51:1133-1143
Background Cough is a common troublesome symptom in asthma which is neuronally mediated. Limosilactobacillus reuteri DSM-17938 (L. reuteri DSM-17938) is a probiotic shown to be effective in pre-clinical models at suppressing neuronal responses to cap