Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Ruth Muchekehu"'
Autor:
Mark Horn, Ruth Muchekehu, Joselyn Del Rosario, Steven Pirie-Shepherd, Allan Kaspar, Dingguo Liu, Venkata Doppalapudi, Trina Osothprarop, Julia Coronella, Haim Moskowitz, Michael Bacica, Lioudmila Campbell, Anouk Dirksen
Publikováno v:
Translational oncology. 6(5)
Poor drug delivery and penetration of antibody-mediated therapies pose significant obstacles to effective treatment of solid tumors. This study explored the role of pharmacokinetics, valency, and molecular weight in maximizing drug delivery. Biodistr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34af362ceb89442cdb636bf9acb59cdc
https://pubmed.ncbi.nlm.nih.gov/24151537
https://pubmed.ncbi.nlm.nih.gov/24151537
Publikováno v:
Cancer Research. 72:4629-4629
Poor drug concentration, distribution and retention pose significant obstacles to effective therapy of solid tumors. Antibody based immunotherapies must balance pharmacokinetics (PK), molecular weight and potency in order to maximize tumor penetratio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::15d3380ffce55401b32bfccac41b7b00
https://doi.org/10.1158/1538-7445.am2012-4629
https://doi.org/10.1158/1538-7445.am2012-4629