Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Ruth McQuillan"'
Autor:
Eldad Agyei‐Manu, Nadege Atkins, Bohee Lee, Jasmin Rostron, Marshall Dozier, Maureen Smith, Ruth McQuillan
Publikováno v:
Health Expectations, Vol 26, Iss 4, Pp 1436-1452 (2023)
Abstract Introduction Despite the growing evidence on patient and public involvement (PPI) in health research, little emphasis has been placed on understanding its quality and appropriateness to evidence synthesis (ES) and systematic reviews (SR). Th
Externí odkaz:
https://doaj.org/article/21d2222860f84f91bec5149e202e7ff3
Autor:
Reagan Lee, Wei Xu, Marshall Dozier, Ruth McQuillan, Evropi Theodoratou, Jonine Figueroa, On Behalf of UNCOVER and the International Partnership for Resilience in CancerSystems (I-PaRCS), Breast Cancer Working Group
Publikováno v:
eLife, Vol 12 (2023)
COVID-19 has strained population breast mammography screening programs that aim to diagnose and treat breast cancers earlier. As the pandemic has affected countries differently, we aimed to quantify changes in breast screening volume and uptake durin
Externí odkaz:
https://doaj.org/article/1fcf2f6ea00d4ce9ba619385ab30611c
Autor:
Bohee Lee, Grace Lewis, Eldad Agyei-Manu, Nadege Atkins, Urmila Bhattacharyya, Marshall Dozier, Jasmin Rostron, Aziz Sheikh, Ruth McQuillan, Evropi Theodoratou
Publikováno v:
European Respiratory Review, Vol 31, Iss 166 (2022)
Background The Joint Committee on Vaccination and Immunisation in the United Kingdom requested an evidence synthesis to investigate the relationship between asthma and coronavirus disease 2019 (COVID-19) outcomes. Objective We conducted a systematic
Externí odkaz:
https://doaj.org/article/736fe0ed38aa4439942f865187bc16a0
Autor:
Charlotte M. Bavuma, Sanctus Musafiri, Pierre-Claver Rutayisire, Loise M. Ng’ang’a, Ruth McQuillan, Sarah H. Wild
Publikováno v:
BMC Endocrine Disorders, Vol 20, Iss 1, Pp 1-10 (2020)
Abstract Background Existing prevention and treatment strategies target the classic types of diabetes yet this approach might not always be appropriate in some settings where atypical phenotypes exist. This study aims to assess the socio-demographic
Externí odkaz:
https://doaj.org/article/b015be7bf7be4cc79fb33781331625e6
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 14, Iss 6, p e0008383 (2020)
BackgroundUrogenital schistosomiasis and HIV/AIDS infections are widespread in sub-Saharan Africa (SSA) leading to substantial morbidity and mortality. The co-occurrence of both diseases has led to the possible hypothesis that urogenital schistosomia
Externí odkaz:
https://doaj.org/article/9c3db962793447f6a53e5047539bb785
Autor:
Emily Weiss, Lina Zgaga, Stephanie Read, Sarah Wild, Malcolm G Dunlop, Harry Campbell, Ruth McQuillan, James F Wilson
Publikováno v:
PLoS ONE, Vol 11, Iss 5, p e0155633 (2016)
Orkney, north of mainland Scotland, has the world's highest prevalence of multiple sclerosis (MS); vitamin D deficiency, a marker of low UV exposure, is also common in Scotland. Strong associations have been identified between vitamin D deficiency an
Externí odkaz:
https://doaj.org/article/621dd6bbf067473080d7ce1f6f01dfa2
Autor:
Jared O'Connell, Deepti Gurdasani, Olivier Delaneau, Nicola Pirastu, Sheila Ulivi, Massimiliano Cocca, Michela Traglia, Jie Huang, Jennifer E Huffman, Igor Rudan, Ruth McQuillan, Ross M Fraser, Harry Campbell, Ozren Polasek, Gershim Asiki, Kenneth Ekoru, Caroline Hayward, Alan F Wright, Veronique Vitart, Pau Navarro, Jean-Francois Zagury, James F Wilson, Daniela Toniolo, Paolo Gasparini, Nicole Soranzo, Manjinder S Sandhu, Jonathan Marchini
Publikováno v:
PLoS Genetics, Vol 10, Iss 4, p e1004234 (2014)
Many existing cohorts contain a range of relatedness between genotyped individuals, either by design or by chance. Haplotype estimation in such cohorts is a central step in many downstream analyses. Using genotypes from six cohorts from isolated popu
Externí odkaz:
https://doaj.org/article/7ad43a93c54740d0857b751de9977374
Autor:
Peter K Joshi, James Prendergast, Ross M Fraser, Jennifer E Huffman, Veronique Vitart, Caroline Hayward, Ruth McQuillan, Dominik Glodzik, Ozren Polašek, Nicholas D Hastie, Igor Rudan, Harry Campbell, Alan F Wright, Chris S Haley, James F Wilson, Pau Navarro
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e68604 (2013)
The analysis of less common variants in genome-wide association studies promises to elucidate complex trait genetics but is hampered by low power to reliably detect association. We show that addition of population-specific exome sequence data to glob
Externí odkaz:
https://doaj.org/article/907409466cd94df49150bc46dd9dcc97
Autor:
Ruth McQuillan, Niina Eklund, Nicola Pirastu, Maris Kuningas, Brian P McEvoy, Tõnu Esko, Tanguy Corre, Gail Davies, Marika Kaakinen, Leo-Pekka Lyytikäinen, Kati Kristiansson, Aki S Havulinna, Martin Gögele, Veronique Vitart, Albert Tenesa, Yurii Aulchenko, Caroline Hayward, Asa Johansson, Mladen Boban, Sheila Ulivi, Antonietta Robino, Vesna Boraska, Wilmar Igl, Sarah H Wild, Lina Zgaga, Najaf Amin, Evropi Theodoratou, Ozren Polašek, Giorgia Girotto, Lorna M Lopez, Cinzia Sala, Jari Lahti, Tiina Laatikainen, Inga Prokopenko, Mart Kals, Jorma Viikari, Jian Yang, Anneli Pouta, Karol Estrada, Albert Hofman, Nelson Freimer, Nicholas G Martin, Mika Kähönen, Lili Milani, Markku Heliövaara, Erkki Vartiainen, Katri Räikkönen, Corrado Masciullo, John M Starr, Andrew A Hicks, Laura Esposito, Ivana Kolčić, Susan M Farrington, Ben Oostra, Tatijana Zemunik, Harry Campbell, Mirna Kirin, Marina Pehlic, Flavio Faletra, David Porteous, Giorgio Pistis, Elisabeth Widén, Veikko Salomaa, Seppo Koskinen, Krista Fischer, Terho Lehtimäki, Andrew Heath, Mark I McCarthy, Fernando Rivadeneira, Grant W Montgomery, Henning Tiemeier, Anna-Liisa Hartikainen, Pamela A F Madden, Pio d'Adamo, Nicholas D Hastie, Ulf Gyllensten, Alan F Wright, Cornelia M van Duijn, Malcolm Dunlop, Igor Rudan, Paolo Gasparini, Peter P Pramstaller, Ian J Deary, Daniela Toniolo, Johan G Eriksson, Antti Jula, Olli T Raitakari, Andres Metspalu, Markus Perola, Marjo-Riitta Järvelin, André Uitterlinden, Peter M Visscher, James F Wilson, ROHgen Consortium
Publikováno v:
PLoS Genetics, Vol 8, Iss 7, p e1002655 (2012)
Stature is a classical and highly heritable complex trait, with 80%-90% of variation explained by genetic factors. In recent years, genome-wide association studies (GWAS) have successfully identified many common additive variants influencing human he
Externí odkaz:
https://doaj.org/article/38213f45313a4782904cad96662f9668
Autor:
Maris Kuningas, Ruth McQuillan, James F Wilson, Albert Hofman, Cornelia M van Duijn, André G Uitterlinden, Henning Tiemeier
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e22580 (2011)
Runs of homozygosity (ROH) are extended tracts of adjacent homozygous single nucleotide polymorphisms (SNPs) that are more common in unrelated individuals than previously thought. It has been proposed that estimating ROH on a genome-wide level, by ma
Externí odkaz:
https://doaj.org/article/54b092d209074c3b83c3fd15fa07f3b8