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Low-density lipoprotein balances T cell metabolism and enhances response to anti-PD-1 blockade in a HCT116 spheroid model

Autor: Nathalie Babl, Joshua Hofbauer, Carina Matos, Florian Voll, Ayse Nur Menevse, Michael Rechenmacher, Ruth Mair, Philipp Beckhove, Wolfgang Herr, Peter J. Siska, Kathrin Renner, Marina Kreutz, Annette Schnell

Publikováno v: Frontiers in Oncology, Vol 13 (2023)

IntroductionThe discovery of immune checkpoints and the development of their specific inhibitors was acclaimed as a major breakthrough in cancer therapy. However, only a limited patient cohort shows sufficient response to therapy. Hence, there is a n

Externí odkaz: https://doaj.org/article/665d9c3a8e194fc4aff448d9891a418f

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Overexpression of IFN-induced protein with tetratricopeptide repeats 3 (IFIT3) in pancreatic cancer: cellular 'pseudoinflammation' contributing to an aggressive phenotype

Autor: Karl-Walter Jauch, Andrea Renner, Yue Zhao, Carsten Jäckel, Christiane Bruns, Peter J. Nelson, Peter Camaj, Ruth Mair, Hanno Niess

Publikováno v: Oncotarget

// Hanno Niess 1 , Peter Camaj 2 , Ruth Mair 1 , Andrea Renner 1 , Yue Zhao 1 , Carsten Jackel 3 , Peter J. Nelson 3 , Karl-Walter Jauch 1 and Christiane J. Bruns 2 1 Department of Surgery, Medical Center of the Ludwig-Maximilians-University, Campus

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af8ce26d1945b0ff384c23b46232ae73
https://doi.org/10.18632/oncotarget.2494

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