Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Ruth Magaye"'
Autor:
Ruth Magaye, Qi Zhou, Linda Bowman, Baobo Zou, Guochuan Mao, Jin Xu, Vincent Castranova, Jinshun Zhao, Min Ding
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e92418 (2014)
While numerous studies have described the pathogenic and carcinogenic effects of nickel compounds, little has been done on the biological effects of metallic nickel. Moreover, the carcinogenetic potential of metallic nickel nanoparticles is unknown.
Externí odkaz:
https://doaj.org/article/b6f3d45c751843b580277b239af9f1a5
Autor:
Kui Liu, Lu Zhang, Xialu Lin, Liangliang Chen, Hongbo Shi, Ruth Magaye, Baobo Zou, Jinshun Zhao
Publikováno v:
PLoS ONE, Vol 9, Iss 1 (2014)
Externí odkaz:
https://doaj.org/article/8101bb29833b43d5879d15b0795402e5
Autor:
Kui Liu, Lu Zhang, Xialu Lin, Liangliang Chen, Hongbo Shi, Ruth Magaye, Baobo Zou, Jinshun Zhao
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e57043 (2013)
BACKGROUND: Due to the possible involvement of Glutathione S-transferase Mu-1 (GSTM1) and Glutathione S-transferase theta-1 (GSTT1) in the detoxification of environmental carcinogens, environmental toxins, and oxidative stress products, genetic polym
Externí odkaz:
https://doaj.org/article/1e172379ec724ab08838ab0b2c32006d
Publikováno v:
Circulation Research. 127
Background: Cardiac fibrosis is one of the hallmarks of cardiac remodelling in cardiomyopathies such as heart Failure (HF). Dyslipidemia plays a role in the progression of HF. The sphingolipid, dihydrosphingosine 1 phosphate (dhS1P) has been shown to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a2d5e619788bcc4c2b0fd054510c54c3
https://doi.org/10.1161/res.127.suppl_1.487
https://doi.org/10.1161/res.127.suppl_1.487
Autor:
Carmen V. Scullino, Stuart M. Pitson, Andrew R Kompa, Christopher A. Reid, David M. Kaye, Bing Hui Wang, Bernard L. Flynn, Feby Savira, Danny Liew, Darren J. Kelly, Li Huang, Xin Xiong, Ruth Magaye
Publikováno v:
Vascular pharmacology. 141
Protein-bound uremic toxins (PBUTs) have adverse effects on vascular function, which is imperative in the progression of cardiovascular and renal diseases. The role of sphingolipids in PBUT-mediated vasculo-endothelial pathophysiology is unclear. Thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b725b23e0fc362f234b595449550265e
https://pubmed.ncbi.nlm.nih.gov/34600152
https://pubmed.ncbi.nlm.nih.gov/34600152
Autor:
John C. Burnett, Ruth Magaye, Danny Liew, Christopher A. Reid, S. Jeson Sangaralingham, Darren J. Kelly, Feby Savira, Andrew R Kompa, David M. Kaye, Bing Hui Wang
Publikováno v:
Br J Pharmacol
Cardiorenal syndrome (CRS) is a multi-organ disease, encompassing heart, kidney and vascular system dysfunction. CRS is a worldwide problem, with high morbidity, mortality, and inflicts a significant burden on the health care system. The pathophysiol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8b366553c5e3d7736202affc85abb8e
https://europepmc.org/articles/PMC7280015/
https://europepmc.org/articles/PMC7280015/
Autor:
Yue Hua, Jingbin Guo, Wei Xiao, Aihua Chen, Kevin W. Huang, Darren J. Kelly, Ying-Chun Zhou, Jake Cornell, Qiang Fu, Danny Liew, Bing Hui Wang, Lu Lu, Ruth Magaye, Christopher M. Reid
Publikováno v:
Clinical and Experimental Pharmacology and Physiology. 44:55-63
Cardiac fibrosis refers to an excessive deposition of extracellular matrix (ECM) in cardiac tissue. Fibrotic tissue is stiffer and less compliant, resulting in subsequent cardiac dysfunction and heart failure. Cardiac fibrosis in the ageing heart may
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::712669846e4cea81d80d115562a033ad
https://doi.org/10.1111/1440-1681.12753
https://doi.org/10.1111/1440-1681.12753
Autor:
Andrew R Kompa, Robert N. Willette, Li Huang, Darren J. Kelly, Ruth Magaye, Xin Xiong, Bing Hui Wang, Feby Savira, Beat M. Jucker
Publikováno v:
Life Sciences. 272:119267
Aims Indoxyl sulfate (IS), a protein-bound uremic toxin, is implicated in endothelial dysfunction, which contributes to adverse cardiovascular events in chronic kidney disease. Apoptosis signal regulating kinase 1 (ASK1) is a reactive oxygen species-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b674a219776502193160fc8117f53ea
https://doi.org/10.1016/j.lfs.2021.119267
https://doi.org/10.1016/j.lfs.2021.119267
In vitro and in vivo evaluation of the toxicities induced by metallic nickel nano and fine particles
Autor:
Ruth Magaye, Yuanliang Gu, Jinshun Zhao, Hong Su, Xia Yue, Hongbo Shi, Qi Zhou, Yafei Wang, Baobo Zou, Guochuan Mao, Jin Xu
Publikováno v:
Journal of Molecular Histology. 47:273-286
Nickel nanoparticles (Ni NPs) have been applied in various fields along with the rapid development of nanotechnology. However, the potential adverse health effects of the Ni NPs are unclear. To investigate the cyto- and genotoxicity and compare the d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c6e42c7d5f8960513b428ebbf577153
https://doi.org/10.1007/s10735-016-9671-6
https://doi.org/10.1007/s10735-016-9671-6
Autor:
Darren J. Kelly, Yue Hua, Bernard L. Flynn, Danny Liew, Feby Savira, Bing Hui Wang, Christopher M. Reid, Ruth Magaye
Publikováno v:
Cellular and molecular life sciences : CMLS. 76(6)
Dihydrosphingolipids refer to sphingolipids early in the biosynthetic pathway that do not contain a C4-trans-double bond in the sphingoid backbone: 3-ketosphinganine (3-ketoSph), dihydrosphingosine (dhSph), dihydrosphingosine-1-phosphate (dhS1P) and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1284d7bf588b8f4ed7ba154488a17032
https://pubmed.ncbi.nlm.nih.gov/30523364
https://pubmed.ncbi.nlm.nih.gov/30523364