Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Ruth M. Risueño"'
Autor:
Laia Cuesta-Casanovas, Jennifer Delgado-Martínez, Josep M. Cornet-Masana, José M. Carbó, Antònia Banús-Mulet, Francesca Guijarro, Jordi Esteve, Ruth M. Risueño
Publikováno v:
Cancer Cell International, Vol 23, Iss 1, Pp 1-18 (2023)
Abstract Background Development of precision medicine requires the identification of easily detectable and druggable biomarkers. Despite recent targeted drug approvals, prognosis of acute myeloid leukemia (AML) patients needs to be greatly improved,
Externí odkaz:
https://doaj.org/article/00026095bd1140f2bb033ebf31627389
Autor:
Oriol Calvete, Julia Mestre, Ruth M. Risueño, Ana Manzanares, Pamela Acha, Blanca Xicoy, Francesc Solé
Publikováno v:
Biomedicines, Vol 11, Iss 12, p 3222 (2023)
Next-generation sequencing (NGS) tools have importantly helped the classification of myelodysplastic syndromes (MDS), guiding the management of patients. However, new concerns are under debate regarding their implementation in routine clinical practi
Externí odkaz:
https://doaj.org/article/4636b85de0d74f138ff07e445d0865a7
Autor:
Iris Aparici Herraiz, Hugo R. Caires, Óscar Castillo-Fernández, Núria Sima, Lourdes Méndez-Mora, Ruth M. Risueño, Jetsumon Sattabongkot, Wanlapa Roobsoong, Aurora Hernández-Machado, Carmen Fernandez-Becerra, Cristina C. Barrias, Hernando A. del Portillo
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Plasmodium vivax is the most widely distributed human malaria parasite representing 36.3% of disease burden in the South-East Asia region and the most predominant species in the region of the Americas. Recent estimates indicate that 3.3 billion of pe
Externí odkaz:
https://doaj.org/article/e135a84b9c1c4a46b90b94e27a1c9f0a
Autor:
Josep M. Cornet-Masana, Antònia Banús-Mulet, José M. Carbó, Miguel Ángel Torrente, Francesca Guijarro, Laia Cuesta-Casanovas, Jordi Esteve, Ruth M. Risueño
Publikováno v:
EBioMedicine, Vol 47, Iss , Pp 221-234 (2019)
Background: Despite great efforts to identify druggable molecular targets for AML, there remains an unmet need for more effective therapies. Methods: An in silico screening was performed using Connectivity Maps to identify FDA-approved drugs that may
Externí odkaz:
https://doaj.org/article/b2c84a711dbd456585fea65b0bb48e74
Autor:
José M. Carbó, Josep M. Cornet-Masana, Laia Cuesta-Casanovas, Jennifer Delgado-Martínez, Antònia Banús-Mulet, Lise Clément-Demange, Carme Serra, Juanlo Catena, Amadeu Llebaria, Jordi Esteve, Ruth M. Risueño
Publikováno v:
Cancers; Volume 15; Issue 6; Pages: 1912
Acute myeloid leukemia (AML) is a heterogeneous hematological cancer characterized by poor prognosis and frequent relapses. Aside from specific mutation-related changes, in AML, the overall function of lysosomes and mitochondria is drastically altere
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::378eda04dc8e34603f1902a3e7f6d3b5
http://hdl.handle.net/10261/306238
http://hdl.handle.net/10261/306238
Autor:
David Perna-Barrull, Laia Gomez-Muñoz, Silvia Rodriguez-Fernandez, Anna Gieras, Rosa M. Ampudia-Carrasco, Lidia Almenara-Fuentes, Ruth M. Risueño, Sergi Querol, Eva Tolosa, Marta Vives-Pi
Publikováno v:
Archivum immunologiae et therapiae experimentalis. 71(1)
Hematopoietic stem cell (HSC) transplantation is crucial to cure hematologic malignancies. Umbilical cord blood (UCB) is a source of stem cells, but 90% of UCB units are discarded due to low cellularity. Improving the engraftment capacities of CD34+
Autor:
Ruth M. Risueño, Lucía Fernández, Antonio Pérez-Martínez, Diego Megías, Joaquin Martinez-Lopez, Alejandra Leivas, Inmaculada Rapado, Manuel Pérez, Rafael Feito Alonso, Alma Guzmán, Laura Sánchez-Vega
Publikováno v:
CANCER IMMUNOLOGY IMMUNOTHERAPY
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
instname
Cancer Immunology, Immunotherapy
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
instname
Cancer Immunology, Immunotherapy
The multiple myeloma (MM) landscape has changed in the last few years, but most patients eventually relapse because current treatment modalities do not target clonogenic stem cells, which are drug-resistant and can self-renew. We hypothesized that si
Autor:
Laia Cuesta-Casanovas, Jennifer Delgado-Martínez, Josep M. Cornet-Masana, José M. Carbó, Lise Clément-Demange, Ruth M. Risueño
Publikováno v:
Cancer Drug Resistance.
Despite the outstanding advances in understanding the biology underlying the pathophysiology of acute myeloid leukemia (AML) and the promising preclinical data published lastly, AML treatment still relies on a classic chemotherapy regimen largely unc
Autor:
Federico Vázquez, Rosa-Maria Ampudia, Silvia Rodriguez-Fernandez, Laia Gomez-Muñoz, David Perna-Barrull, Marta Vives-Pi, Ruth M. Risueño, Daniel Maspoch, Irma Pujol-Autonell, Mary Cano-Sarabia, Eva Aguilera, Adrian Villalba
Publikováno v:
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Scientific Reports
Digital.CSIC. Repositorio Institucional del CSIC
instname
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Universitat Autònoma de Barcelona
Scientific Reports
Digital.CSIC. Repositorio Institucional del CSIC
instname
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Type 1 diabetes is an autoimmune disease caused by the destruction of the insulin-producing β-cells. To revert type 1 diabetes, the suppression of the autoimmune attack should be combined with a β-cell replacement strategy. It has been previously d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60fa56655a866ea18cee51de4a9ff1a9
https://ddd.uab.cat/record/236025
https://ddd.uab.cat/record/236025
Autor:
Josep Maria Cornet-Masana, Ruth M. Risueño, Francesca Guijarro, Antònia Banús-Mulet, Josep M. Carbó, Jordi Esteve, Laia Cuesta-Casanovas, Miguel Ángel Torrente
Publikováno v:
SSRN Electronic Journal.
Background: Despite great efforts to identify druggable molecular targets for hematological neoplasias, there remains an unmet need for more effective therapies. Methods: We screened FDA-approved drugs that may revert an early transformation gene sig