Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Ruth M. Dixon"'
Autor:
John Posner, Ruth M. Dixon, Barry C. Weatherley, Emma J. Seaber, Gary R. Layton, Richard W. Peck, Paul E. Rolan, Stephen D. Jackson
Publikováno v:
Clinical Pharmacology & Therapeutics. 63:342-353
Objective Zolmitriptan is a selective 5HT1B/1D-agonist for the treatment of migraine. In this study we investigated the cardiovascular and central nervous system effects and the pharmacokinetics of zolmitriptan in young and elderly adults. Methods Tw
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cb485c3b7782f207ea805ec54fd5cdc
https://doi.org/10.1016/s0009-9236(98)90166-7
https://doi.org/10.1016/s0009-9236(98)90166-7
Publikováno v:
Journal of Organometallic Chemistry. 437:227-237
The 1 H NMR spectra of a series of alkylcobalamins, principally 2-oxy substituted, including adenosyl- and ribosylcobalamin, have been analysed with particular attention to the conformation of the alkyl moiety. The enantioselectivity of formation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::466747207d57153f14f0f95b4b6aa866
https://doi.org/10.1016/0022-328x(92)83446-o
https://doi.org/10.1016/0022-328x(92)83446-o
Publikováno v:
Journal of the Chemical Society, Chemical Communications. :70
Thermolysis or photolysis of 4,5-dihydroxy-2,2-dimethylpentyl(pyridine)cobaloxime (1a) at either pH 3 or 9 affords 4,4-dimethylpentanal (15–45%) in a model system for B12-dependent diol dehydrase.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b630d33177c6cd8351d0fbde6aac66af
https://doi.org/10.1039/c39900000070
https://doi.org/10.1039/c39900000070
Publikováno v:
Journal of the Chemical Society, Chemical Communications. :603
The crystal structure of (R)- and (S)-2,3-dihydroxypropylcobalamin show Co–Cα–Cβ angles of 119.6 ± 1.7 and 113.6 ± 2.1° and Co–C bond lengths of 2.002(23) and 2.079(30)A, respectively; comparison with the structure of the B12 coenzyme aden
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::90c48161cf3c16d3eb85cc2153b59eb2
https://doi.org/10.1039/c39850000603
https://doi.org/10.1039/c39850000603
Publikováno v:
Journal of the Chemical Society, Chemical Communications. :243
Stereoisomerically pure samples of (2R)- and (2S)-2-hydroxypropyl-, (2R)- and (2S)-2,3-dihydroxypropyl-, (3S)-3,4-dihydroxybutyl-, and (4S)-4,5-dihydroxypentyl-cobalamin have been synthesised by allowing cob(I) alamin to react with the appropriate op
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a9711297357f19633bc8819c1e88aa5e
https://doi.org/10.1039/c39830000243
https://doi.org/10.1039/c39830000243