Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Ruth M. Darrow"'
Autor:
Ruth M. Darrow, Rekha Rangarajan, Alison Ziesel, John C. Lang, Paul Wong, Daniel T. Organisciak, Christine M. Rapp
Publikováno v:
Photochemistry and Photobiology. 88:1396-1407
Mineral supplements are often included in multivitamin preparations because of their beneficial effects on metabolism. In this study, we used an animal model of light-induced retinal degeneration to test for photoreceptor cell protection by the essen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ac45e2b13829ce8b48836185dd8e7db
https://doi.org/10.1111/j.1751-1097.2012.01134.x
https://doi.org/10.1111/j.1751-1097.2012.01134.x
Publikováno v:
Photochemistry and Photobiology. 75:547-553
This study investigated a possible circadian rhythm of light damage susceptibility in photoreceptors of both cyclic light-reared and dark-reared rats. A single exposure to intense green light was administered, beginning either in the early light peri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f9ab26980238c27d07f9a0b8e971959
https://doi.org/10.1562/0031-8655(2002)0750547efacro2.0.co2
https://doi.org/10.1562/0031-8655(2002)0750547efacro2.0.co2
Autor:
Daniel T. Organisciak, Stanley A Hazen, Ruth M. Darrow, Silvia C. Finnemann, George Hoppe, Maria Febbraio, Roy L. Silverstein, Eugene A. Podrez, Robert G. Salomon, Mingjiang Sun, Suresh P. Annangudi, Lian Shan
Publikováno v:
Journal of Biological Chemistry. 281:4222-4230
Clearance by the retinal pigment epithelium (RPE) of shed photoreceptor outer segments (OSs), a tissue with one of the highest turnover rates in the body, is critical to the maintenance and normal function of the retina. We hypothesized that there is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b90b1176378bf757636547a186f02d40
https://doi.org/10.1074/jbc.m509769200
https://doi.org/10.1074/jbc.m509769200
Autor:
Dennis J. Stuehr, Lin Yan, John W. Crabb, Kulwant S. Aulak, K.A. West, Daniel T. Organisciak, Hirokazu Sakaguchi, Joe G. Hollyfield, Ruth M. Darrow, Masaru Miyagi
Publikováno v:
Molecular & Cellular Proteomics. 1:293-303
As part of ongoing efforts to better understand the role of protein oxidative modifications in retinal pathology, protein nitration in retina has been compared between rats exposed to damaging light or maintained in the dark. In the course of the res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0ad87037c246479554c89c65c607356
https://doi.org/10.1074/mcp.m100034-mcp200
https://doi.org/10.1074/mcp.m100034-mcp200
Publikováno v:
Photochemistry and Photobiology. 70:261-268
In the rat, photoreceptor cell death from exposure to intense visible light can be prevented by prior treatment with antioxidants. In this study we subjected albino rats raised in dim cyclic light and rats made more susceptible to light damage by rea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8cba596361e5b11a7e1ab7e9e4cfef46
https://doi.org/10.1111/j.1751-1097.1999.tb07998.x
https://doi.org/10.1111/j.1751-1097.1999.tb07998.x
Publikováno v:
Photochemistry and Photobiology. 69:91-98
— Intense visible light can damage retinal photoreceptor cells by photochemical or thermal processes, leading to cell death. The precise mechanism of light-induced damage is unknown; however, oxidative stress is thought to be involved, based on the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a4e7684b24a8c06ecfd000d35765f3e7
https://doi.org/10.1111/j.1751-1097.1999.tb05311.x
https://doi.org/10.1111/j.1751-1097.1999.tb05311.x
Autor:
Joe G. Hollyfield, Ruth M. Darrow, Masaru Miyagi, Daniel T. Organisciak, Hirokazu Sakaguchi, John W. Crabb, John S. Crabb
Publikováno v:
Experimental Eye Research. 76:131-133
Toward a better understanding of light-induced photoreceptor damage, the crystallin content of rat retina was examined following intense light exposure. Nine crystallin species were identified by mass spectrometric analysis of rat retina fractionated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3763ba07b2c666760cf2fb883bd8c0d
https://doi.org/10.1016/s0014-4835(02)00249-x
https://doi.org/10.1016/s0014-4835(02)00249-x
Autor:
Yoshikazu Imanishi, Daniel T. Organisciak, Rong Zeng, Haixu Tang, Ruth M. Darrow, Masaru Miyagi, Vikram Palamalai, Dagmar Hajkova, Quanhu Sheng, Chao Yuan, K. C. Sekhar Rao
Acute light-induced photoreceptor degeneration has been studied in experimental animals as a model for photoreceptor cell loss in human retinal degenerative diseases. Light absorption by rhodopsin in rod photoreceptor outer segments (OS) induces oxid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc8c56e63d97402472becace0d0380dc
https://europepmc.org/articles/PMC2818867/
https://europepmc.org/articles/PMC2818867/
Publikováno v:
Current Eye Research. 11:231-241
To assess the protective effect of ascorbic acid in retinal light damage of rats, we have determined the uptake and retinal tissue distributions of its L- and D- stereoisomers following interperitoneal or intraocular injections. The effects of intens
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72f3be1c416ec9dd4b352b239133d01c
https://doi.org/10.3109/02713689209001774
https://doi.org/10.3109/02713689209001774
Publikováno v:
Experimental Eye Research. 53:773-779
Long-term environmental light-mediated changes in visual cell transduction proteins were studied to assess the influence of rearing environment on their levels and their potential effects on intense light-induced retinal damage. The levels of rhodops
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6906872dca550005fbc6cd26e40bb389
https://doi.org/10.1016/0014-4835(91)90113-s
https://doi.org/10.1016/0014-4835(91)90113-s