Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Ruth M Klement"'
Autor:
Martha V Koerner, Florian M Pauler, Quanah J Hudson, Federica Santoro, Anna Sawicka, Philipp M Guenzl, Stefan H Stricker, Yvonne M Schichl, Paulina A Latos, Ruth M Klement, Katarzyna E Warczok, Jacek Wojciechowski, Christian Seiser, Robert Kralovics, Denise P Barlow
Publikováno v:
PLoS Genetics, Vol 8, Iss 3, p e1002540 (2012)
A CpG island (CGI) lies at the 5' end of the Airn macro non-protein-coding (nc) RNA that represses the flanking Igf2r promoter in cis on paternally inherited chromosomes. In addition to being modified on maternally inherited chromosomes by a DNA meth
Externí odkaz:
https://doaj.org/article/101388fd6d6d45abbce01052c01e8d80
Autor:
Katarzyna E. Warczok, Daniela Mayer, Florian M. Pauler, Denise P. Barlow, Ruth M. Klement, Alexey Stukalov, Federica Santoro
Publikováno v:
Development. 140:1184-1195
The imprinted Airn macro long non-coding (lnc) RNA is an established example of a cis-silencing lncRNA. Airn expression is necessary to initiate paternal-specific silencing of the Igf2r gene, which is followed by gain of a somatic DNA methylation imp
Autor:
Paulina A. Latos, Denise P. Barlow, Ruth M. Klement, Roman R. Stocsits, Pawel Pasierbek, Martha V. Koerner, Karin Aumayr, Quanah J. Hudson, Stefan H. Stricker, H. Başak Şenergin, Katarzyna E. Warczok, Florian M. Pauler, Wolfgang Allhoff
Publikováno v:
Science. 338:1469-1472
Long Noncoding RNAs The past 5 years have uncovered thousands of long (>100 nucleotides) noncoding RNAs (lncRNAs) outpacing our understanding of their functions and mechanisms in regulating the genome. Lee (p. 1435 ) reviews the known and suspected m