Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Ruth M Kennan"'
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e47932 (2012)
Dichelobacter nodosus is the principal causative agent of ovine footrot and its extracellular proteases are major virulence factors. Virulent isolates of D. nodosus secrete three subtilisin-like serine proteases: AprV2, AprV5 and BprV. These enzymes
Externí odkaz:
https://doaj.org/article/333c5b2405ac485792b8591d4378baa5
Autor:
Ruth M Kennan, Wilson Wong, Om P Dhungyel, Xiaoyan Han, David Wong, Dane Parker, Carlos J Rosado, Ruby H P Law, Sheena McGowan, Shane B Reeve, Vita Levina, Glenn A Powers, Robert N Pike, Stephen P Bottomley, A Ian Smith, Ian Marsh, Richard J Whittington, James C Whisstock, Corrine J Porter, Julian I Rood
Publikováno v:
PLoS Pathogens, Vol 6, Iss 11, p e1001210 (2010)
Many bacterial pathogens produce extracellular proteases that degrade the extracellular matrix of the host and therefore are involved in disease pathogenesis. Dichelobacter nodosus is the causative agent of ovine footrot, a highly contagious disease
Externí odkaz:
https://doaj.org/article/468ef5017baf44698c215e055cd8aa6f
Autor:
Ruth M. Kennan, Marianne Gilhuus, Sara Frosth, Torsten Seemann, Om P. Dhungyel, Richard J. Whittington, John D. Boyce, David R. Powell, Anna Aspán, Hannah J. Jørgensen, Dieter M. Bulach, Julian I. Rood
Publikováno v:
mBio, Vol 10, Iss 5 (2019)
Externí odkaz:
https://doaj.org/article/96fec4619a05429d9f506583952e1d8e
Autor:
Ruth M. Kennan, Marianne Gilhuus, Sara Frosth, Torsten Seemann, Om P. Dhungyel, Richard J. Whittington, John D. Boyce, David R. Powell, Anna Aspán, Hannah J. Jørgensen, Dieter M. Bulach, Julian I. Rood
Publikováno v:
mBio, Vol 5, Iss 5 (2014)
ABSTRACT Footrot is a contagious, debilitating disease of sheep, causing major economic losses in most sheep-producing countries. The causative agent is the Gram-negative anaerobe Dichelobacter nodosus. Depending on the virulence of the infective bac
Externí odkaz:
https://doaj.org/article/aa1139c88c8c43d6a83929178d1670c6
Autor:
Julian I. Rood, Om P. Dhungyel, Marianne Gilhuus, Anna Aspán, Dieter M. Bulach, Richard Whittington, Torsten Seemann, Hannah J. Jørgensen, David R. Powell, Ruth M. Kennan, John D. Boyce, Sara Frosth
Publikováno v:
mBio, Vol 10, Iss 5 (2019)
mBio, Vol 10, Iss 5, p e02560-19 (2019)
mBio
mBio, Vol 10, Iss 5, p e02560-19 (2019)
mBio
Footrot is a contagious, debilitating disease of sheep, causing major economic losses in most sheep-producing countries. The causative agent is the Gram-negative anaerobe Dichelobacter nodosus. Depending on the virulence of the infective bacterial st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e742efedf8fb3403995e297e37164c6
https://doi.org/10.1128/mbio.02560-19
https://doi.org/10.1128/mbio.02560-19
Publikováno v:
Small Ruminant Research. 195:106305
Footrot is a contagious disease of sheep and other small ruminants. The causative agent, Dichelobacter nodosus, is transmitted between hooves via contaminated pasture and soil. However, the bacterium cannot invade the epidermis unless it is compromis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4421e74e9ddff34bb1c0eb7c2736ea03
https://doi.org/10.1016/j.smallrumres.2020.106305
https://doi.org/10.1016/j.smallrumres.2020.106305
Autor:
Wilson Wong, Shane Reeve, Robert N. Pike, Julian I. Rood, Corrine Joy Porter, Cyril F. Reboul, Lakshmi C. Wijeyewickrema, David Steer, James C. Whisstock, A. Ian Smith, Ruth M. Kennan
Publikováno v:
Journal of Biological Chemistry. 286:42180-42187
The ovine footrot pathogen, Dichelobacter nodosus, secretes three subtilisin-like proteases that play an important role in the pathogenesis of footrot through their ability to mediate tissue destruction. Virulent and benign strains of D. nodosus secr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5d9d694af733afcf222c35ea91936c6
https://doi.org/10.1074/jbc.m111.298711
https://doi.org/10.1074/jbc.m111.298711
Autor:
Wilson Wong, James C. Whisstock, Ruth M. Kennan, Carlos J. Rosado, Corrine Joy Porter, Julian I. Rood
Publikováno v:
Acta Crystallographica Section F Structural Biology and Crystallization Communications. 66:289-293
Dichelobacter nodosus is the principal causative agent of ovine footrot, a disease of significant economic importance to the sheep industry. D. nodosus secretes a number of subtilisin-like serine proteases which mediate tissue damage and presumably c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a28e3b746f51f28533d2230ea98072e
https://doi.org/10.1107/s1744309110000333
https://doi.org/10.1107/s1744309110000333
Publikováno v:
Monash University
The objective of this study was to develop an understanding of the molecular mechanisms by which type IV fimbrial biogenesis, natural transformation, and protease secretion are linked in the ovine foot rot pathogen, Dichelobacter nodosus . We have sh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f431143aec867f62b3059915c861cc7
https://doi.org/10.1128/jb.00138-07
https://doi.org/10.1128/jb.00138-07
Autor:
Hervé Tettelin, Hoda Khouri, Keith Al-Hasani, Ramana Madupu, Ben Adler, Xiaoyan Han, Julian I. Rood, Jonathan H. Badger, Ian T. Paulsen, Steven P. Bottomley, J. Glenn Songer, Victoria McCarl, Tara Holley, Garry S. A. Myers, Richard Whittington, Qinghu Ren, Jeremy D. Selengut, William C. Nelson, Robert T. DeBoy, Ruth M. Kennan, John D. Boyce, Yasmin Ali Mohamoud, Nadia Fedorova, Torsten Seemann, Dane Parker
Publikováno v:
Nature Biotechnology. 25:569-575
Dichelobacter nodosus causes ovine footrot, a disease that leads to severe economic losses in the wool and meat industries. We sequenced its 1.4-Mb genome, the smallest known genome of an anaerobe. It differs markedly from small genomes of intracellu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b395633591498438541f89eacb649468
https://doi.org/10.1038/nbt1302
https://doi.org/10.1038/nbt1302