Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Ruth M, O'Regan"'
Autor:
Hamza Bakhtiar, Marina N. Sharifi, Kyle T. Helzer, Yue Shi, Matthew L. Bootsma, Tianfu A. Shang, Matthew R. Chrostek, Tracy J. Berg, S. Carson Callahan, Viridiana Carreno, Grace C. Blitzer, Malinda T. West, Ruth M. O’Regan, Kari B. Wisinski, Martin Sjöström, Shuang G. Zhao
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-10 (2024)
Abstract In preclinical studies, p53 loss of function impacts chemotherapy response, but this has not been consistently validated clinically. We trained a TP53-loss phenocopy gene expression signature from pan-cancer clinical samples in the TCGA. In
Externí odkaz:
https://doaj.org/article/b735ca97c9414b91b5344298927abc08
Autor:
Ticiana A. Leal, Marina N. Sharifi, Nancy Chan, Robert Wesolowski, Anita A. Turk, Justine Y. Bruce, Ruth M. O'Regan, Jens Eickhoff, Lisa M. Barroilhet, Jyoti Malhotra, Janice Mehnert, Eugenia Girda, Elizabeth Wiley, Natalie Schmitz, Shannon Andrews, Glenn Liu, Kari B. Wisinski
Publikováno v:
Cancer Medicine, Vol 11, Iss 21, Pp 3969-3981 (2022)
Abstract Background Inhibitors of poly(ADP‐ribose) polymerase (PARP) proteins potentiate antitumor activity of platinum chemotherapy. This study sought to determine the safety and tolerability of PARP inhibitor talazoparib with carboplatin and pacl
Externí odkaz:
https://doaj.org/article/d110893465fc4eceb9dd0c7b44d3c53f
Autor:
Zeni Kharel, Omar P. Nemer, Wang Xi, Bimala Upadhayaya, Carla I. Falkson, Ruth M. O’Regan, Ajay Dhakal
Publikováno v:
Breast Disease. 41:255-260
Inflammatory breast cancer (IBC) is a rare variety of breast cancer accounting for two percent of breast cancer diagnoses in the United States. It is characterized by peau d’orange, breast edema and erythema on physical examination and dermal lymph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::86a53527dd49c6405e62e2e7667a53b0
https://doi.org/10.3233/bd-210041
https://doi.org/10.3233/bd-210041
Autor:
Mark E. Burkard, Ning Jin, David J. Beebe, Beth A. Weaver, Lee G. Wilke, Ruth M. O'Regan, Amye J. Tevaarwerk, Kari B. Wisinski, Mouhita Humayun, Rachel E. Yan, Christina M. Scribano, John B. Tucker, Roshan X. Norman, Robert F. Lera, Stephanie M. McGregor, Baraa K. Manasrah, Yang Hu
Multinucleated H2B-RFP Tub-GFP MDA-MB-231 Multipolar Division
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10cde5cfaa91872e322c4a8409bc24b3
https://doi.org/10.1158/1535-7163.22522734.v1
https://doi.org/10.1158/1535-7163.22522734.v1
Autor:
Mark E. Burkard, Ning Jin, David J. Beebe, Beth A. Weaver, Lee G. Wilke, Ruth M. O'Regan, Amye J. Tevaarwerk, Kari B. Wisinski, Mouhita Humayun, Rachel E. Yan, Christina M. Scribano, John B. Tucker, Roshan X. Norman, Robert F. Lera, Stephanie M. McGregor, Baraa K. Manasrah, Yang Hu
Mononucleated H2B-RFP Tub-GFP MDA-MB-231 Bipolar Division
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cb7ae04f6851d34fc80c9ea3ad040bc
https://doi.org/10.1158/1535-7163.22522740.v1
https://doi.org/10.1158/1535-7163.22522740.v1
Autor:
Sami Diab, Vassiliki Karantza, Ella Kleynerman, Dongyuan Xing, Claudio Savulsky, Grace Wang, Yuan Yuan, Debra A. Patt, Eleni Andreopoulou, Sharon T. Wilks, Peter A. Kaufman, Ruth M. O'Regan, Michaela L. Tsai, Gursel Aktan, David R. D'Adamo, Virginia G. Kaklamani, Kevin Kalinsky, Sara M. Tolaney
Purpose:As monotherapies, eribulin (chemotherapy) and pembrolizumab (immunotherapy) have shown promise for patients with metastatic triple-negative breast cancer (mTNBC). This phase Ib/II study examined eribulin plus pembrolizumab as a potential mTNB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::703b5a9c0f4a055b8338f260ccadb13b
https://doi.org/10.1158/1078-0432.c.6530040.v1
https://doi.org/10.1158/1078-0432.c.6530040.v1
Autor:
Sami Diab, Vassiliki Karantza, Ella Kleynerman, Dongyuan Xing, Claudio Savulsky, Grace Wang, Yuan Yuan, Debra A. Patt, Eleni Andreopoulou, Sharon T. Wilks, Peter A. Kaufman, Ruth M. O'Regan, Michaela L. Tsai, Gursel Aktan, David R. D'Adamo, Virginia G. Kaklamani, Kevin Kalinsky, Sara M. Tolaney
Supplementary Information
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2651cad31791dcbd5d9c34941f502a4e
https://doi.org/10.1158/1078-0432.22478769.v1
https://doi.org/10.1158/1078-0432.22478769.v1
Autor:
Gustavo A. Miranda-Carboni, Susan A. Krum, Victoria Seewaldt, Tiffany N. Seagroves, William E. Lowry, Ruth M. O'Regan, Lily Yang, Lisa D. Yee, Robert Cardiff, Andrew C. White, Raisa I. Krutilina, Hilaire C. Barch, Stephan Lehr, Joseph K. Gray, Wendy Silva, Julio Silva, William L. Kuenzinger, Stephanie Runke, Jackelyn A. Alva-Ornelas, Peter Wend, Iram Fatima, Ikbale El Ayachi
Triple-negative breast cancer (TNBC) commonly develops resistance to chemotherapy, yet markers predictive of chemoresistance in this disease are lacking. Here, we define WNT10B-dependent biomarkers for β-CATENIN/HMGA2/EZH2 signaling predictive of re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cfbb347fc17e589e41a0e43ba5161ad7
https://doi.org/10.1158/0008-5472.c.6511163.v1
https://doi.org/10.1158/0008-5472.c.6511163.v1
Autor:
Gustavo A. Miranda-Carboni, Susan A. Krum, Victoria Seewaldt, Tiffany N. Seagroves, William E. Lowry, Ruth M. O'Regan, Lily Yang, Lisa D. Yee, Robert Cardiff, Andrew C. White, Raisa I. Krutilina, Hilaire C. Barch, Stephan Lehr, Joseph K. Gray, Wendy Silva, Julio Silva, William L. Kuenzinger, Stephanie Runke, Jackelyn A. Alva-Ornelas, Peter Wend, Iram Fatima, Ikbale El Ayachi
Supplementary Section: 1) Seven supplementary figures and legends: A. Supplementary figure S1: TCGA analysis of WNT10B network. B. Supplementary figure S2: Human IHC analysis of WNT10B, HMGA2 and EZH2. C. Supplementary figure S3: Mouse IHC analysis o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86d588ad2842fb0c7dd56c5ab217cf0a
https://doi.org/10.1158/0008-5472.22422239.v1
https://doi.org/10.1158/0008-5472.22422239.v1
Autor:
Dipali Sharma, Ruth M. O'Regan, Frank A. Anania, Didier Merlin, Brandi B. Knight, LaTonia Taliaferro-Smith, Neeraj K. Saxena
Supplementary Figure Legends 1-2 from Bidirectional Crosstalk between Leptin and Insulin-like Growth Factor-I Signaling Promotes Invasion and Migration of Breast Cancer Cells via Transactivation of Epidermal Growth Factor Receptor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c555ed24fb0a9112890afa80162ba18d
https://doi.org/10.1158/0008-5472.22375989
https://doi.org/10.1158/0008-5472.22375989