Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Ruth Kiro"'
Publikováno v:
RNA Biology. 11:42-44
The clustered regularly interspaced short palindromic repeats (CRISPR)-CRISPR-associated (Cas) system has recently been used to engineer genomes of various organisms, but surprisingly, not those of bacteriophages (phages). Here we present a method to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18bae72b64e2e5e5a74459176c1cbc16
https://doi.org/10.4161/rna.27766
https://doi.org/10.4161/rna.27766
Publikováno v:
Nanotoxicology. 3:98-108
A panel of genetically-engineered Escherichia coli biosensor bacteria, responsive to chemical stressors inducing heat shock, DNA damage, oxidative stress (peroxide- and superoxide-type) and fatty acid metabolism interference, was used to characterize
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b44933032102e40d8500206e7ccd56a3
https://doi.org/10.1080/17435390802546089
https://doi.org/10.1080/17435390802546089
Autor:
Michael Gershovits, Ruth Kiro, Miriam Manor, Shahar Molshanski-Mor, Rotem Edgar, Udi Qimron, Tal Pupko, Ido Yosef, Mia Laserson
Today's arsenal of antibiotics is ineffective against some emerging strains of antibiotic-resistant pathogens. Novel inhibitors of bacterial growth therefore need to be found. The target of such bacterial-growth inhibitors must be identified, and one
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::277985531027c2939693fab37d22f454
https://europepmc.org/articles/PMC4284602/
https://europepmc.org/articles/PMC4284602/
Publikováno v:
Bacteriophage. 4(1)
Bacterial resistance to antibiotics is an emerging threat requiring urgent solutions. Ever since their discovery, lytic bacteriophages have been suggested as therapeutic agents, but their application faces various obstacles: sequestration of the phag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a630b0149aaec2489732c46384e4b082
https://pubmed.ncbi.nlm.nih.gov/24653944
https://pubmed.ncbi.nlm.nih.gov/24653944
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 110(48)
Bacteriophages take over host resources primarily via the activity of proteins expressed early in infection. One of these proteins, produced by the Escherichia coli phage T7, is gene product (Gp) 0.4. Here, we show that Gp0.4 is a direct inhibitor of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::848d150eb991b64791a23e88ee4a590b
https://pubmed.ncbi.nlm.nih.gov/24218612
https://pubmed.ncbi.nlm.nih.gov/24218612
Publikováno v:
Sberro, Hila; Leavitt, Azita; Kiro, Ruth; Koh, Eugene; Peleg, Yoav; Qimron, Udi; et al.(2013). Discovery of functional toxin/antitoxin systems in bacteria by shotgun cloning. Molecular Cell, 50(1). Lawrence Berkeley National Laboratory: Lawrence Berkeley National Laboratory. Retrieved from: http://www.escholarship.org/uc/item/5qg388pt
Summary Toxin-antitoxin (TA) modules, composed of a toxic protein and a counteracting antitoxin, play important roles in bacterial physiology. We examined the experimental insertion of 1.5 million genes from 388 microbial genomes into an Escherichia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2487b34008ebc431df7cef460ce9e254
http://www.escholarship.org/uc/item/5qg388pt
http://www.escholarship.org/uc/item/5qg388pt
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 108(50)
Prokaryotic DNA arrays arranged as clustered regularly interspaced short palindromic repeats (CRISPR), along with their associated proteins, provide prokaryotes with adaptive immunity by RNA-mediated targeting of alien DNA or RNA matching the sequenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecc6bfb1a077a91c99b65b8514a112ed
https://pubmed.ncbi.nlm.nih.gov/22114197
https://pubmed.ncbi.nlm.nih.gov/22114197