Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Ruth Jinfen Chai"'
Autor:
Ruth Jinfen Chai, Hendrikje Werner, Peter Yiqing Li, Yin Loon Lee, Khaing Thet Nyein, Irina Solovei, Tuan Danh Anh Luu, Bhavya Sharma, Raju Navasankari, Martina Maric, Lois Yu En Sim, Ying Jie Loh, Edita Aliwarga, Jason Wen Long Cheong, Alexandre Chojnowski, Matias Ilmari Autio, Yu Haiyang, Kenneth Kian Boon Tan, Choong Tat Keng, Shi Ling Ng, Wei Leong Chew, Michael Ferenczi, Brian Burke, Roger Sik Yin Foo, Colin L. Stewart
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Mutations in the LaminA gene are the second most common inherited cause of Dilated Cardiomyopathy, a major form of heart failure. Here the authors show that disruption of the nuclear protein SUN1 in cardiomyocytes, by AAV mediated transduction of a S
Externí odkaz:
https://doaj.org/article/c8e8b6f93e7b442686a2d1ede70d7399
Autor:
Tsui Han Loo, Xiaoqian Ye, Ruth Jinfen Chai, Mitsuteru Ito, Gisèle Bonne, Anne C Ferguson-Smith, Colin L Stewart
Publikováno v:
eLife, Vol 8 (2019)
Here we show that a major muscle specific isoform of the murine LINC complex protein SUN1 is required for efficient muscle regeneration. The nucleoplasmic domain of the isoform specifically binds to and inhibits Drosha, a key component of the micropr
Externí odkaz:
https://doaj.org/article/91a0a0b2e6f24b3b9e111f25c07c8652
Autor:
Xingang Wang, Anne L. Robertson, Jingyu Li, Ruth Jinfen Chai, Wang Haishan, Pranvera Sadiku, Nikolay V. Ogryzko, Martin Everett, Kanagasundaram Yoganathan, Hongbo Robert Luo, Stephen A. Renshaw, Philip W. Ingham
Publikováno v:
Disease Models & Mechanisms, Vol 7, Iss 1, Pp 163-169 (2014)
Cell migration is fundamental to the inflammatory response, but uncontrolled cell migration and excess recruitment of neutrophils and other leukocytes can cause damage to the tissue. Here we describe the use of an in vivo model – the Tg(mpx:GFP)i11
Externí odkaz:
https://doaj.org/article/a8517d4267004992a957ba250976bbc1
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e28090 (2011)
Reasons for the progressive age-related loss of skeletal muscle mass and function, namely sarcopenia, are complex. Few studies describe sarcopenia in mice, although this species is the mammalian model of choice for genetic intervention and developmen
Externí odkaz:
https://doaj.org/article/f8ae235a9bf8457e965607b3f102f747
Publikováno v:
International Journal of Bioprinting.
Patients with severe burns, which cause extensive damage to their skin, require rapid intervention to prevent life-threatening hypothermia, infection, and fluid loss. Current treatments typically involve surgical excision of the burned skin and recon
Publikováno v:
Materials Today: Proceedings. 70:72-77
Autor:
Alexandre Chojnowski, Colin L. Stewart, Lois Yu En Sim, Yin Loon Lee, Choong Tat Keng, Matias Ilmari Autio, Tuan Danh Anh Luu, Ying Jie Loh, Khaing Thet Nyein, Roger Foo, Michael A. Ferenczi, Brian Burke, Shi Ling Ng, Kenneth Kian Boon Tan, Bhavya Sharma, Irina Solovei, Yu Haiyang, Jason Wen Long Cheong, Ruth Jinfen Chai, Peter Yiqing Li, Edita Aliwarga, Raju Navasankari, Martina Maric, Hendrikje Werner, Wei Leong Chew
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Mutations in the LaminA gene are a common cause of monogenic dilated cardiomyopathy. Here we show that mice with a cardiomyocyte-specific Lmna deletion develop cardiac failure and die within 3–4 weeks after inducing the mutation. When the same Lmna
Publikováno v:
Biomaterials. 276
Hydrogels are used in many biomedical applications, including regenerative medicine and surgical training phantoms. However, the ability to shape these materials into complex anatomical structures using additive manufacturing is limited in part by th
Autor:
Anne C. Ferguson-Smith, Gisèle Bonne, Colin L. Stewart, Mitsuteru Ito, Ruth Jinfen Chai, Xiaoqian Ye, Tsui Han Loo
Publikováno v:
eLife
eLife, 2019, 8, ⟨10.7554/eLife.49485⟩
eLife, eLife Sciences Publication, 2019, 8, ⟨10.7554/eLife.49485⟩
eLife, Vol 8 (2019)
eLife, 2019, 8, ⟨10.7554/eLife.49485⟩
eLife, eLife Sciences Publication, 2019, 8, ⟨10.7554/eLife.49485⟩
eLife, Vol 8 (2019)
International audience; Here we show that a major muscle specific isoform of the murine LINC complex protein SUN1 is required for efficient muscle regeneration. The nucleoplasmic domain of the isoform specifically binds to and inhibits Drosha, a key
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::902276e7b4d5cd66b456bd39c019a083
https://hal.sorbonne-universite.fr/hal-02573415/document
https://hal.sorbonne-universite.fr/hal-02573415/document