Zobrazeno 1 - 10
of 103
pro vyhledávání: '"Ruth J Williams"'
Publikováno v:
PLoS Computational Biology, Vol 18, Iss 4, p e1009961 (2022)
Epigenetic cell memory allows distinct gene expression patterns to persist in different cell types despite a common genotype. Although different patterns can be maintained by the concerted action of transcription factors (TFs), it was proposed that l
Externí odkaz:
https://doaj.org/article/9268620195c6434b9c440254ef93da4a
Autor:
Natalie A Cookson, William H Mather, Tal Danino, Octavio Mondragón‐Palomino, Ruth J Williams, Lev S Tsimring, Jeff Hasty
Publikováno v:
Molecular Systems Biology, Vol 7, Iss 1, Pp 1-9 (2011)
Abstract High‐throughput technologies have led to the generation of complex wiring diagrams as a post‐sequencing paradigm for depicting the interactions between vast and diverse cellular species. While these diagrams are useful for analyzing biol
Externí odkaz:
https://doaj.org/article/7509c9323d874f10a48122a309c2e61e
Publikováno v:
Mathematics of Control, Signals, and Systems. 35:399-432
In the last decade, the interactions among histone modifications and DNA methylation and their effect on the DNA structure, i.e., chromatin state, have been identified as key mediators for the maintenance of cell identity, defined as epigenetic cell
Autor:
Amber L. Puha, Ruth J. Williams
Publikováno v:
Stochastic Systems, Vol 6, Iss 2, Pp 251-300 (2016)
In this paper, we develop a new approach to studying the asymptotic behavior of fluid model solutions for critically loaded processor sharing queues. For this, we introduce a notion of relative entropy associated with measure-valued fluid model solut
Externí odkaz:
https://doaj.org/article/3fe21f89c87a42e084702ebfbe761682
Publikováno v:
Bulletin of Mathematical Biology. 85
Continuous-time Markov chains are frequently used as stochastic models for chemical reaction networks, especially in the growing field of systems biology. A fundamental problem for these Stochastic Chemical Reaction Networks (SCRNs) is to understand
Publikováno v:
2022 IEEE 61st Conference on Decision and Control (CDC).
Publikováno v:
2022 European Control Conference (ECC).
Autor:
Yingjia Fu, Ruth J. Williams
Publikováno v:
The Annals of Applied Probability. 32
Publikováno v:
Applied Mathematics & Optimization. 84:175-214
Unlimited access to a motorway network can, in overloaded conditions, cause a loss of throughput. Ramp metering, by controlling access to the motorway at onramps, can help avoid this loss of throughput. The queues that form at onramps are dependent o
Autor:
Yingjia Fu, Ruth J. Williams
Publikováno v:
Stochastic Systems. 10:251-273
This work concerns the asymptotic behavior of solutions to a (strictly) subcritical fluid model for a data communication network, where file sizes are generally distributed and the network operates under a fair bandwidth-sharing policy. Here we consi