Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Ruth E. Beattie"'
Autor:
Adrian J. Mogg, Elizabeth A. Folly, C E J Mill, J P Beck, Lisa M. Broad, Ruth E. Beattie, Maria-Jesus Blanco
Publikováno v:
British Journal of Pharmacology. 168:1015-1029
Background and Purpose Evidence suggests that phosphorylation of TRPV1 is an important component underlying its aberrant activation in pathological pain states. To date, the detailed pharmacology of diverse TRPV1 receptor agonists and antagonists has
Publikováno v:
European Journal of Pharmacology. 641:114-122
TRPV1 (transient receptor potential vanilloid 1) is a ligand-gated ion channel expressed predominantly in nociceptive primary afferents that plays a key role in pain processing. In vivo activation of TRPV1 receptors by natural agonists like capsaicin
Autor:
Gordon I. McPhie, Ruud Zwart, Elizabeth A. Folly, Emanuele Sher, Laura R. Johnson, Ruth E. Beattie, Kathy H. Pearson, Stephen G. Volsen, Emma Bell, Non M. Evans, Giovanni Benedetti, Lisa M. Broad, Suchira Bose, Neil S. Millar, Peter J. Craig
Publikováno v:
European Journal of Pharmacology. 502:31-40
A chimera comprising the N-terminal region of the human alpha7 nicotinic acetylcholine receptor, fused to the transmembrane/C-terminal domains of the mouse serotonin 5-HT3 receptor, was constructed. Injection of the chimera cDNA into Xenopus oocytes,
Identification and cellular localisation of voltage-operated calcium channels in immature rat testis
Autor:
Angela D'Agostino, Emanuele Sher, Kerry L. Price, Matthew Kemp, Ruth E. Beattie, Alessandra Fragale, S. G. Volsen, Matthew B. Reeves, Salvatore Aguanno, Peter J. Craig
Publikováno v:
Molecular and Cellular Endocrinology. 162:25-33
Sertoli cells regulate the spermatogenic process mainly through the secretion of a complex fluid into the lumen of the seminiferous tubules behind the blood–testis barrier, containing many of the essential proteins necessary for maintenance and mat
Autor:
Edward Perez-Reyes, Annette C. Dolphin, Ruth E. Beattie, Jung-Ha Lee, Peter J. Craig, L. L. Cribbs, J. Richards, S. G. Volsen, Christopher N. Wyatt
Publikováno v:
The Journal of Physiology. 519:35-45
1 The effect has been examined of the accessory α2-δ and β subunits on the properties of α1G currents expressed in monkey COS-7 cells and Xenopus oocytes. 2 In immunocytochemical experiments, the co-expression of α2-δ increased plasma membrane
Autor:
M D Banerjee, Elizabeth A. Folly, Peter J. Craig, S L Carney, Edward Perez-Reyes, S. G. Volsen, Ruth E. Beattie, Emanuele Sher, Matthew B. Reeves, John V. Priestley
Publikováno v:
European Journal of Neuroscience. 11:2949-2964
The molecular identity of a gene which encodes the pore-forming subunit (alpha1G) of a member of the family of low-voltage-activated, T-type, voltage-dependent calcium channels has been described recently. Although northern mRNA analyses have shown a
Autor:
S. G. Volsen, Niki C. Day, W. Smith, Peter J. Craig, Pamela J. Shaw, Michael M. Harpold, Steve B. Ellis, Paul G. Ince, Ruth E. Beattie, Alison L. McCormack
Publikováno v:
Molecular Brain Research. 60:259-269
The beta subunits of voltage-dependent calcium channels (VDCC) modulate the electrophysiology and cell surface expression of pore-forming alpha1 subunits. In the present study we have investigated the distribution of beta1,beta2,beta3 and beta4 in th
Autor:
W. Smith, Stephen G. Volsen, Andrew D. McAinsh, John V. Priestley, Peter J. Craig, Alison L. McCormack, Sharon Averill, Ruth E. Beattie, E. Rebecca Longbottom, Jennifer Lai Yee Yip
Publikováno v:
Journal of Comparative Neurology. 397:251-267
The alpha(1) subunit provides both the voltage-sensing mechanism and the ion pore of voltage-dependent calcium channels. Of the six classes of alpha(1) subunit cloned to date, alpha)1A) is the subject of debate in terms of its functional correlate, a
Autor:
Régis C. Lambert, Michel De Waard, Yves Maulet, Jérôme Mouton, S. G. Volsen, Anne Feltz, Ruth E. Beattie
Publikováno v:
The Journal of Neuroscience. 17:6621-6628
At the molecular level, our knowledge of the low voltage-activated Ca2+channel (T-type) has made little progress. Using an antisense strategy, we investigated the possibility that the T-type channels have a structure similar to high voltage-activated
Autor:
William R. Smith, Michael M. Harpold, Steven B. Ellis, Ruth E. Beattie, Dawn Smith, Alison L. McCormack, Alison Gillespie, J. Paul Burnett, Stephen G. Volsen, Samantha E. Gillard
Publikováno v:
Brain Research Protocols. 1:307-319
Neuronal voltage-dependent calcium channels (VDCCs) each comprising of alpha 1, alpha 2 delta, and beta subunits, are one mechanism by which excitable cells regulate the flux of calcium ions across the cell membrane following depolarisation Studies h