Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Ruth Dumpit"'
Autor:
Deyong Jia, Zhicheng Zhou, Oh-Joon Kwon, Li Zhang, Xing Wei, Yiqun Zhang, Mingyang Yi, Martine P. Roudier, Mary C. Regier, Ruth Dumpit, Peter S. Nelson, Mark Headley, Lawrence True, Daniel W. Lin, Colm Morrissey, Chad J. Creighton, Li Xin
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Forkhead transcription factor FoxF2 plays a crucial role in the development of organs derived from primitive gut. Here the authors show that reduction of Foxf2 expression in stromal cells is associated with high grade prostate cancer and that increas
Externí odkaz:
https://doaj.org/article/6ef1b8477dc94cb884e5bb6309eb3423
Autor:
Radhika A. Patel, Ilsa Coleman, Martine P. Roudier, Eric Q. Konnick, Brian Hanratty, Ruth Dumpit, Jared M. Lucas, Lisa S. Ang, Jin-Yih Low, Maria S. Tretiakova, Gavin Ha, John K. Lee, Lawrence D. True, Angelo M. De Marzo, Peter S. Nelson, Colm Morrissey, Colin C. Pritchard, Michael C. Haffner
Publikováno v:
Cancer Res Commun
Anaplastic lymphoma kinase (ALK) is a tyrosine kinase with genomic and expression changes in many solid tumors. ALK inhibition is the first-line therapy for lung cancers with ALK alterations, and an effective therapy in other tumor types, but has not
Autor:
Michael C. Haffner, Colin C. Pritchard, Colm Morrissey, Peter S. Nelson, Angelo M. De Marzo, Lawrence D. True, John K. Lee, Gavin Ha, Maria S. Tretiakova, Jin-Yih Low, Lisa S. Ang, Jared M. Lucas, Ruth Dumpit, Brian Hanratty, Eric Q. Konnick, Martine P. Roudier, Ilsa Coleman, Radhika A. Patel
Anaplastic lymphoma kinase (ALK) is a tyrosine kinase with genomic and expression changes in many solid tumors. ALK inhibition is the first-line therapy for lung cancers with ALK alterations, and an effective therapy in other tumor types, but has not
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25646326e6abdc2a05ef2261ba0945d7
https://doi.org/10.1158/2767-9764.c.6550595.v1
https://doi.org/10.1158/2767-9764.c.6550595.v1
Autor:
Michael C. Haffner, Colin C. Pritchard, Colm Morrissey, Peter S. Nelson, Angelo M. De Marzo, Lawrence D. True, John K. Lee, Gavin Ha, Maria S. Tretiakova, Jin-Yih Low, Lisa S. Ang, Jared M. Lucas, Ruth Dumpit, Brian Hanratty, Eric Q. Konnick, Martine P. Roudier, Ilsa Coleman, Radhika A. Patel
Supplementary Figures 1-19, Tables 1-2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2162f12980b1a0f8d2e9939fc711ed1b
https://doi.org/10.1158/2767-9764.22544270.v1
https://doi.org/10.1158/2767-9764.22544270.v1
Autor:
Colm Morrissey, Robert L. Vessella, Peter S. Nelson, Paul H. Lange, Martine Roudier, Bruce Montgomery, Celestia S. Higano, Bryce Lakely, Lisly Chéry, Eva Corey, Ruth Dumpit, Hung-Ming Lam, Jared M. Lucas, Lori Kollath, Lawrence D. True, Lisha G. Brown, Ilsa M. Coleman, Xiaotun Zhang
A cluster analysis of adenocarcinoma and neuronal CRPC metastases (n=71). The CHGA+/SYP+ sites cluster together (highlighted in orange (AR+) and yellow (AR-)). Genes between CHGA- vs. CHGA+/SYP+ were compared and considered differentially expressed w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7529d95eab92fa6304f50eb9a2a8b6f4
https://doi.org/10.1158/1078-0432.22461821
https://doi.org/10.1158/1078-0432.22461821
Autor:
Colm Morrissey, Robert L. Vessella, Peter S. Nelson, Paul H. Lange, Martine Roudier, Bruce Montgomery, Celestia S. Higano, Bryce Lakely, Lisly Chéry, Eva Corey, Ruth Dumpit, Hung-Ming Lam, Jared M. Lucas, Lori Kollath, Lawrence D. True, Lisha G. Brown, Ilsa M. Coleman, Xiaotun Zhang
AgilentTM oligo array expression analysis of thirty-seven genes with >2.5-fold differential expression common to 5 CHGA+/SYP+/AR- and 5 CHGA+/SYP+/AR+ CRPC metastases when compared to 61 CHGA- or CHGA+/SYP- CRPC metastases. Mean-centered ratios of ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::070400fe62c4f7380467785426dbf00f
https://doi.org/10.1158/1078-0432.22461815
https://doi.org/10.1158/1078-0432.22461815
Autor:
Peter S. Nelson, Lawrence D. True, Eva Corey, Colm Morrissey, Steven P. Balk, Trevor M. Penning, Alvin M. Matsumoto, Lisa Ang, Ruth Dumpit, John Burns, Jon Bartlett, Maria Tretiakova, Heather E. Biehl, Daniel Tamae, Xiaotun Zhang, Brett T. Marck, Susana Hernandez, Ailin Zhang, Elahe A. Mostaghel
Purpose:Tumor androgens in castration-resistant prostate cancer (CRPC) reflect de novo intratumoral synthesis or adrenal androgens. We used C.B.-17 SCID mice in which we observed adrenal CYP17A activity to isolate the impact of adrenal steroids on CR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a13bd3518a817d49f4a2936c7c306b13
https://doi.org/10.1158/1078-0432.c.6528972.v1
https://doi.org/10.1158/1078-0432.c.6528972.v1
Autor:
Peter S. Nelson, Lawrence D. True, Eva Corey, Colm Morrissey, Steven P. Balk, Trevor M. Penning, Alvin M. Matsumoto, Lisa Ang, Ruth Dumpit, John Burns, Jon Bartlett, Maria Tretiakova, Heather E. Biehl, Daniel Tamae, Xiaotun Zhang, Brett T. Marck, Susana Hernandez, Ailin Zhang, Elahe A. Mostaghel
Supplementary Figs S1-S6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09b3138353c483cbd25be3f9eee5ba5a
https://doi.org/10.1158/1078-0432.22475019
https://doi.org/10.1158/1078-0432.22475019
Autor:
Colm Morrissey, Robert L. Vessella, Peter S. Nelson, Paul H. Lange, Martine Roudier, Bruce Montgomery, Celestia S. Higano, Bryce Lakely, Lisly Chéry, Eva Corey, Ruth Dumpit, Hung-Ming Lam, Jared M. Lucas, Lori Kollath, Lawrence D. True, Lisha G. Brown, Ilsa M. Coleman, Xiaotun Zhang
(A) Hypothetical interactions between NE-associated transcription factors upregulated in CHGA+/SYP+/AR- tumors that promote the AR- NE phenotype. (B) A Venn diagram comparing genes with a SAM score >2.5 between CHGA- and CHGA+/SYP- metastases and CHG
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8abf5544d5b7711b1da367f9d86d79be
https://doi.org/10.1158/1078-0432.22461818
https://doi.org/10.1158/1078-0432.22461818
Autor:
Colm Morrissey, Robert L. Vessella, Peter S. Nelson, Paul H. Lange, Martine Roudier, Bruce Montgomery, Celestia S. Higano, Bryce Lakely, Lisly Chéry, Eva Corey, Ruth Dumpit, Hung-Ming Lam, Jared M. Lucas, Lori Kollath, Lawrence D. True, Lisha G. Brown, Ilsa M. Coleman, Xiaotun Zhang
Purpose: The neuroendocrine phenotype is associated with the development of metastatic castration-resistant prostate cancer (CRPC). Our objective was to characterize the molecular features of the neuroendocrine phenotype in CRPC.Experimental Design:
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab319fbcebd8f46cdbaf3582091b7722
https://doi.org/10.1158/1078-0432.c.6524915
https://doi.org/10.1158/1078-0432.c.6524915