Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Ruth Dempsey"'
Autor:
Ruth Dempsey, Gregory Rodrigo, Florence Vonmoos, Irfan Gunduz, Maxim Belushkin, Marco Esposito
Publikováno v:
Toxicology Reports, Vol 10, Iss , Pp 195-205 (2023)
Heated tobacco products (HTP) have become increasingly common in many countries worldwide. The principle of heating tobacco, without combustion, to produce a nicotine-containing aerosol with remarkably reduced levels of other known toxins, compared t
Externí odkaz:
https://doaj.org/article/215ebd7bc838441b91cc28a785ff4907
Autor:
Timo Hagemeister, Joerg Diekmann, Detlef J. Veltel, Boris P. Mueller, Franz J. Tewes, Arno Knorr, Wolf Reininghaus, Hans-Juergen Haussmann, Ewald Roemer, Regina Stabbert, Pavel Pospisil, Christian Euchenhofer, Ruth Dempsey
Publikováno v:
Toxicology in Vitro. 42:222-246
Tobacco smoke is a complex mixture with over 8700 identified constituents. Smoking causes many diseases including lung cancer, cardiovascular disease, and chronic obstructive pulmonary disease. However, the mechanisms of how cigarette smoke impacts d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14c7fb700e57c8fd04acf1fc7e6551b4
https://doi.org/10.1016/j.tiv.2017.04.003
https://doi.org/10.1016/j.tiv.2017.04.003
Publikováno v:
Beiträge zur Tabakforschung International, Vol 27, Iss 5, Pp 4-32 (2017)
Summary The goal of the present work is to determine if menthol and non-menthol cigarette smokers differ with respect to time to first cigarette (TTFC) and successful smoking cessation via a meta-analysis of published results. For 13 independent esti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5578a000017d81e940c3427c9e42f4e3
https://doaj.org/article/092752c910a149499ea997dba72aa4b2
https://doaj.org/article/092752c910a149499ea997dba72aa4b2
Autor:
Ulrike Kogel, Gregory Vuillaume, Patrick Vanscheeuwijck, Gregory Rodrigo, Stefan Lebrun, Marco Esposito, Ruth Dempsey, Julia Hoeng, Patrice Leroy, Bjoern Titz, Jenny Ho, Monali Bera, Manuel C. Peitsch, Alberto Oviedo, Wei Teck Tan, Nikolai V. Ivanov, Florian Martin
Publikováno v:
Regulatory Toxicology and Pharmacology. 81:S93-S122
The toxicity of a mentholated version of the Tobacco Heating System (THS2.2M), a candidate modified risk tobacco product (MRTP), was characterized in a 90-day OECD inhalation study. Differential gene and protein expression analysis of nasal epitheliu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca12a135a371598ae2bd8c3941cbd5ae
Autor:
Volker Zenzen, Edgar Trelles Sticken, Christian Schunck, Ewald Roemer, Kathrin Luedemann, Lynda L. Conroy, Ruth Dempsey
Publikováno v:
Toxicology Mechanisms and Methods. 25:320-333
Total particulate matter (TPM) and the gas-vapor phase (GVP) of mainstream smoke from the Reference Cigarette 3R4F were assayed in the cytokinesis-block in vitro micronucleus (MN) assay and the in vitro chromosome aberration (CA) assay, both using V7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::827e94b80623a950b5a77a92a5a10203
https://doi.org/10.3109/15376516.2015.1037413
https://doi.org/10.3109/15376516.2015.1037413
Autor:
Ruth Dempsey, Kris Meurrens, Ewald Roemer, H. Weiler, Matthias K. Schorp, J.-J. Piadé, Patrick Vanscheeuwijck
Publikováno v:
Regulatory Toxicology and Pharmacology. 70:S26-S40
A typical Indonesian kretek cigarette brand and an experimental kretek reference cigarette were compared to the reference cigarette 2R4F in two 90-day inhalation studies. Male and female rats were exposed nose-only to mainstream smoke for 6 hours dai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61998057dc3c156fb99d61683b123a92
https://doi.org/10.1016/j.yrtph.2014.09.013
https://doi.org/10.1016/j.yrtph.2014.09.013
Autor:
A. Deger Evans, Susanne Weber, G. Hornig, Ruth Dempsey, J.-J. Piadé, E. Trelles-Sticken, Heike Schramke, Matthias K. Schorp, H. Völkel, Ewald Roemer, Sandra Wittke
Publikováno v:
Regulatory Toxicology and Pharmacology. 70:S15-S25
Two commercial kretek cigarettes typical for the Indonesian market and a reference kretek cigarette were compared to the American-blended reference cigarette 2R4F by smoke chemistry characterization and in vitro cytotoxicity and mutagenicity assessme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fff872639170812a3cd1409cbc389ee7
Autor:
H. Weiler, Ewald Roemer, An Berges, Kris Meurrens, Patrick Vanscheeuwijck, Ruth Dempsey, Matthias K. Schorp, Heike Schramke, J. Hirter
Publikováno v:
Regulatory Toxicology and Pharmacology. 70:S81-S89
The biological activity of mainstream smoke from experimental kretek cigarettes with and without three mixes of ingredients was assessed in a 90-day rat inhalation study and in a 4-day in vivo micronucleus assay. 350 ingredients, commonly used in var
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b818a5b7cd7d134ae08060d630aad42
https://doi.org/10.1016/j.yrtph.2014.09.014
https://doi.org/10.1016/j.yrtph.2014.09.014
Autor:
Zheng Sponsiello-Wang, Ruth Dempsey, Gerd Kallischnigg, Rolf Weitkunat, Christopher R. E. Coggins
Publikováno v:
Beiträge zur Tabakforschung International, Vol 25, Iss 7, Pp 638-648 (2013)
The assessment of cumulative exposure based on collecting information on the history of active cigarette smoking has been and is being undertaken in a variety of ways. While a very detailed assessment may be required for studies with a focus on parti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80fa4e4a864e5db900eba5e20cbd1e32
https://doaj.org/article/7aaa9cf5735545febe9583966e437da2
https://doaj.org/article/7aaa9cf5735545febe9583966e437da2
Publikováno v:
Regulatory Toxicology and Pharmacology. 64:S1-S10
The following series of papers presents an extensive assessment of the Electrically Heated Cigarette Smoking System EHCSS series-K cigarette vs. conventional lit-end cigarettes (CC) as an example for an extended testing strategy for evaluation of red
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cba7397d0a70746c9922ae2ef37af57c
https://doi.org/10.1016/j.yrtph.2012.08.008
https://doi.org/10.1016/j.yrtph.2012.08.008