Neuronal Receptors Display Cytoskeleton-Independent Directed Motion on the Plasma Membrane

Autor: Ruth D. Taylor, Martin Heine, Nigel J. Emptage, Laura C. Andreae

Publikováno v: iScience, Vol 10, Iss , Pp 234-244 (2018)

Summary: Directed transport of transmembrane proteins is generally believed to occur via intracellular transport vesicles. However, using single-particle tracking in rat hippocampal neurons with a pH-sensitive quantum dot probe that specifically repo

Externí odkaz: https://doaj.org/article/3d7da8a9a6db4aa096d02c02288e1654

Δ9-tetrahydrocannabinol and 2-AG decreases neurite outgrowth and differentially affects ERK1/2 and Akt signaling in hiPSC-derived cortical neurons

Autor: Samuel E. Taylor, Lucia Dutan, Laura C. Andreae, Sagnik Bhattacharyya, Deepak Srivastava, Noel J. Buckley, Carole Shum, Jack Price, Ruth D. Taylor, Katherine Warre-Cornish, Emily Annuario

Publikováno v: Shum, C, Dutan, L, Annuario, E, Warre-Cornish, K, Taylor, S E, Taylor, R D, Andreae, L C, Buckley, N J, Price, J, Bhattacharyya, S & Srivastava, D P 2020, ' Δ 9-tetrahydrocannabinol and 2-AG decreases neurite outgrowth and differentially affects ERK1/2 and Akt signaling in hiPSC-derived cortical neurons ', Molecular and Cellular Neuroscience, vol. 103, 103463 . https://doi.org/10.1016/j.mcn.2019.103463

Endocannabinoids regulate different aspects of neurodevelopment. In utero exposure to the exogenous psychoactive cannabinoid Δ9-tetrahydrocannabinol (Δ9-THC), has been linked with abnormal cortical development in animal models. However, much less i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4df105b5023a37b446741b8654cb892
https://doi.org/10.1016/j.mcn.2019.103463

Stem cell-derived neurons from autistic individuals with SHANK3 mutation show morphogenetic abnormalities during early development

Autor: Laura C. Andreae, Stefan Aigner, Nick J. F. Gatford, Deepak Srivastava, Annie Kathuria, Jack Price, Ravi Jagasia, Paulina Nowosiad, Ruth D. Taylor, Walter Lucchesi

Publikováno v: Molecular Psychiatry
Kathuria, A, Nowosiad, P, Jagasia, R, Aigner, S, Roberts, R D T, Andreae, L C, Gatford, N J F, Lucchesi, W, Srivastava, D P & Price, J 2018, ' Stem Cell-derived neurons from autistic individuals with SHANK3 mutation show morphogenetic abnormalities during early development ', Molecular Psychiatry, vol. 23, no. 3, pp. 735-746 . https://doi.org/10.1038/mp.2017.185

Shank3 is a structural protein found predominantly at the post-synaptic density. Mutations in the SHANK3 gene have been associated with risk for autism spectrum disorder (ASD). We generated induced pluripotent stem cells (iPSCs) from control individu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7bb7b79f3e1945f5a026929e93f30a5
http://europepmc.org/articles/PMC5822449

Neuronal receptors display cytoskeleton-independent directed motion on the plasma membrane

Autor: Martin Heine, Laura C. Andreae, Ruth D. Taylor, Nigel J. Emptage

Publikováno v: Taylor, R D, Heine, M, Emptage, N J & Andreae, L C 2018, ' Neuronal Receptors Display Cytoskeleton-Independent Directed Motion on the Plasma Membrane ', iScience, vol. 10, pp. 234-244 . https://doi.org/10.1016/j.isci.2018.12.001
iScience
iScience, Vol 10, Iss, Pp 234-244 (2018)
iScience, 10:234-244

Summary Directed transport of transmembrane proteins is generally believed to occur via intracellular transport vesicles. However, using single-particle tracking in rat hippocampal neurons with a pH-sensitive quantum dot probe that specifically repor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ed9ed684d9e98d6add883a28c623dfc
https://ora.ox.ac.uk/objects/uuid:24e1ee65-91fb-45b9-aed6-d0c4cfd6c9aa

The Influence of a Visit on Attitude and Behavior towards Nature Conservation

Autor: Ruth D. Taylor

Publikováno v: Visitor Studies. 6:163-171

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5b7af99be5b968b79df537f1fc0b2544
https://doi.org/10.1080/10645579309444690