Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Ruth Conde-Garrosa"'
Autor:
Stefanie K. Wculek, Joaquín Amores-Iniesta, Ruth Conde-Garrosa, Sofía C. Khouili, Ignacio Melero, David Sancho
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-16 (2019)
Abstract Background The manipulation of dendritic cells (DCs) for cancer vaccination has not reached its full potential, despite the revolution in cancer immunotherapy. DCs are fundamental for CD8+ T cell activation, which relies on cross-presentatio
Externí odkaz:
https://doaj.org/article/08387f0f988b409dbb749b5ce8ed67b3
Autor:
Ruth Conde-Garrosa, David Sancho, Santos Mañes, Alfonso R Sanchez-Paulete, Francisco J Cueto, Carlos del Fresno, Paola Brandi, Alexis J. Combes, Elena Hernández-García, Michel Enamorado, Christian P Bromley, Manuel J Gomez, Santiago Zelenay, Salvador Iborra, Matthew F. Krummel
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 5 (2021)
Background Conventional type 1 dendritic cells (cDC1s) are central to antitumor immunity and their presence in the tumor microenvironment associates with improved outcomes in patients with cancer. DNGR-1 (CLEC9A) is a dead cell-sensing receptor highl
Externí odkaz:
https://doaj.org/article/7174fcff49ec4c968e5c2cd9447b8742
Autor:
Sofía C. Khouili, Emma C.L. Cook, Elena Hernández-García, María Martínez-López, Ruth Conde-Garrosa, Salvador Iborra
Publikováno v:
Cell Reports, Vol 33, Iss 9, Pp 108468- (2020)
Summary: Intracellular pathogens have evolved strategies to evade detection by cytotoxic CD8+ T lymphocytes (CTLs). Here, we ask whether Leishmania parasites trigger the SHP-1-FcRγ chain inhibitory axis to dampen antigen cross-presentation in dendri
Externí odkaz:
https://doaj.org/article/c59568341b2f4dc597b1bf14e68d210e
Autor:
Helena M. Izquierdo, Paola Brandi, Manuel-José Gómez, Ruth Conde-Garrosa, Elena Priego, Michel Enamorado, Sarai Martínez-Cano, Iria Sánchez, Laura Conejero, Daniel Jimenez-Carretero, Silvia Martín-Puig, Martin Guilliams, David Sancho
Publikováno v:
Cell Reports, Vol 24, Iss 7, Pp 1738-1746 (2018)
Summary: The rapid transit from hypoxia to normoxia in the lung that follows the first breath in newborn mice coincides with alveolar macrophage (AM) differentiation. However, whether sensing of oxygen affects AM maturation and function has not been
Externí odkaz:
https://doaj.org/article/c9d11d4f274940618ebe34423d921468
Autor:
Elena Hernández-García, Francisco J. Cueto, Emma C. L. Cook, Ana Redondo-Urzainqui, Sara Charro-Zanca, Iñaki Robles-Vera, Ruth Conde-Garrosa, Ivana Nikolić, Guadalupe Sabio, David Sancho, Salvador Iborra
Publikováno v:
Repisalud
Instituto de Salud Carlos III (ISCIII)
Cellular and Molecular Immunology
Instituto de Salud Carlos III (ISCIII)
Cellular and Molecular Immunology
Conventional dendritic cells (cDCs) scan and integrate environmental cues in almost every tissue, including exogenous metabolic signals. While cDCs are critical in maintaining immune balance, their role in preserving energy homeostasis is unclear. He
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56b8365d0c9466e55e63f4a0a506bd04
http://hdl.handle.net/20.500.12105/15098
http://hdl.handle.net/20.500.12105/15098
Autor:
Alexis J. Combes, Santiago Zelenay, Christian P. Bromley, Matthew F. Krummel, Ignacio Melero, Paola Brandi, Alfonso R. Sánchez-Paulete, Carlos del Fresno, Manuel Gómez, Elena Hernández-García, Francisco J. Cueto, Michel Enamorado, Ruth Conde-Garrosa, Salvador Iborra, David Sancho, Santos Mañes
Publikováno v:
Repisalud
Instituto de Salud Carlos III (ISCIII)
Bromley, C 2021, ' DNGR-1 limits Flt3L-mediated antitumor immunity by restraining tumor-infiltrating type I conventional dendritic cells ', Journal for ImmunoTherapy of Cancer . https://doi.org/10.1136/jitc-2020-002054
Journal for Immunotherapy of Cancer
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 5 (2021)
Journal for immunotherapy of cancer, vol 9, iss 5
Instituto de Salud Carlos III (ISCIII)
Bromley, C 2021, ' DNGR-1 limits Flt3L-mediated antitumor immunity by restraining tumor-infiltrating type I conventional dendritic cells ', Journal for ImmunoTherapy of Cancer . https://doi.org/10.1136/jitc-2020-002054
Journal for Immunotherapy of Cancer
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 5 (2021)
Journal for immunotherapy of cancer, vol 9, iss 5
Conventional type 1 dendritic cells (cDC1s) are central to antitumor immunity and their presence in the tumor microenvironment associates with improved outcomes in patients with cancer. DNGR-1 (CLEC9A) is a dead cell-sensing receptor highly restricte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e719150dc3d908f46d05f4443ec98bd
http://hdl.handle.net/20.500.12105/15091
http://hdl.handle.net/20.500.12105/15091
Autor:
María Martínez-López, Emma C. L. Cook, Elena Hernández-García, Sofía C. Khouili, Salvador Iborra, Ruth Conde-Garrosa
Publikováno v:
Cell Reports, Vol 33, Iss 9, Pp 108468-(2020)
Repisalud
Instituto de Salud Carlos III (ISCIII)
Repisalud
Instituto de Salud Carlos III (ISCIII)
Intracellular pathogens have evolved strategies to evade detection by cytotoxic CD8+ T lymphocytes (CTLs). Here, we ask whether Leishmania parasites trigger the SHP-1-FcRγ chain inhibitory axis to dampen antigen cross-presentation in dendritic cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22d9ee02aced76038f76543b1711d039
https://pubmed.ncbi.nlm.nih.gov/33264612
https://pubmed.ncbi.nlm.nih.gov/33264612
Autor:
Sofía C. Khouili, Ruth Conde-Garrosa, Elena Hernández-García, Salvador Iborra, Emma C. L. Cook, María Martínez-López
Publikováno v:
SSRN Electronic Journal.
Pathogens that establish intracellular niches may have evolved strategies to prevent their detection by cytotoxic CD8+ T lymphocytes (CTL), which in some cases requires antigen cross-presentation by dendritic cells (DC). Here, we asked whether Leishm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5fbd9e3c908c56520dcfb695c17a0ad3
https://doi.org/10.2139/ssrn.3645487
https://doi.org/10.2139/ssrn.3645487
Autor:
Joaquín Amores-Iniesta, Ignacio Melero, Stefanie K. Wculek, Ruth Conde-Garrosa, Sofía C. Khouili, David Sancho
Publikováno v:
Journal for Immunotherapy of Cancer
Journal for ImmunoTherapy of Cancer
Dadun. Depósito Académico Digital de la Universidad de Navarra
Consejo Superior de Investigaciones Científicas (CSIC)
Repisalud
Instituto de Salud Carlos III (ISCIII)
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-16 (2019)
Journal for ImmunoTherapy of Cancer
Dadun. Depósito Académico Digital de la Universidad de Navarra
Consejo Superior de Investigaciones Científicas (CSIC)
Repisalud
Instituto de Salud Carlos III (ISCIII)
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-16 (2019)
BACKGROUND: The manipulation of dendritic cells (DCs) for cancer vaccination has not reached its full potential, despite the revolution in cancer immunotherapy. DCs are fundamental for CD8+ T cell activation, which relies on cross-presentation of exo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cdb0b79a5522edca1af326cd6f180f7
https://hdl.handle.net/20.500.12105/7504
https://hdl.handle.net/20.500.12105/7504
Autor:
Michel Enamorado, David Sancho, Francisco J. Cueto, María Martínez-López, Sofía C. Khouili, Ruth Conde-Garrosa, Salvador Iborra, Carlos del Fresno
Publikováno v:
Immunity. 45:847-860
Despite the crucial role of tissue-resident memory T (Trm) cells in protective immunity, their priming remains poorly understood. Here, we have shown differential priming requirements for Trm versus circulating memory CD8+ T cells. In vaccinia cutane
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c02c22a132a65668d9e9d7eae7aed036
https://doi.org/10.1016/j.immuni.2016.08.019
https://doi.org/10.1016/j.immuni.2016.08.019