Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Ruth C. R. Meex"'
Autor:
Kenneth Pasmans, Michiel E. Adriaens, Peter Olinga, Ramon Langen, Sander S. Rensen, Frank G. Schaap, Steven W. M. Olde Damink, Florian Caiment, Luc J. C. van Loon, Ellen E. Blaak, Ruth C. R. Meex
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
Individuals with hepatic steatosis often display several metabolic abnormalities including insulin resistance and muscle atrophy. Previously, we found that hepatic steatosis results in an altered hepatokine secretion profile, thereby inducing skeleta
Externí odkaz:
https://doaj.org/article/9cdec5062300492798606c6e4819818a
Publikováno v:
Obesity Reviews. 23
Maintaining good glycemic control to prevent complications is crucial in people with type 2 diabetes and in people with prediabetes and in the general population. Different strategies to improve glycemic control involve the prescription of blood gluc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fc4c73b6e521539672978505e56cee2
https://doi.org/10.1111/obr.13486
https://doi.org/10.1111/obr.13486
Publikováno v:
Nature Reviews Endocrinology. 15(5):261-273
Evidence is accumulating that the gut microbiome is involved in the aetiology of obesity and obesity-related complications such as nonalcoholic fatty liver disease (NAFLD), insulin resistance and type 2 diabetes mellitus (T2DM). The gut microbiota is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::590f36e59cfa1adb4b9d6b7b746a18e8
https://doi.org/10.1038/s41574-019-0156-z
https://doi.org/10.1038/s41574-019-0156-z
Autor:
Matthew J. Watt, Jennifer Chi Yi Lo, Ruth C. R. Meex, Magdalene K. Montgomery, Stacey N Keenan, Andrew Ryan, Shuai Nie
Publikováno v:
Diabetes, 68(3), 543-555. American Diabetes Association
Defects in hepatic lipid metabolism cause nonalcoholic fatty liver disease and insulin resistance, and these pathologies are closely linked. Regulation of lipid droplet metabolism is central to the control of intracellular fatty acid fluxes, and peri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3283a8ebe207a69d725d652cea05d9ca
https://doi.org/10.2337/db18-0670
https://doi.org/10.2337/db18-0670
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e103062 (2014)
Lipolysis involves the sequential breakdown of fatty acids from triacylglycerol and is increased during energy stress such as exercise. Adipose triglyceride lipase (ATGL) is a key regulator of skeletal muscle lipolysis and perilipin (PLIN) 5 is postu
Externí odkaz:
https://doaj.org/article/286f42fe2a434126ab0ec28c2a2f371c
Autor:
Ellen E. Blaak, Ruth C. R. Meex
Publikováno v:
Molecular Nutrition & Food Research
Non‐Alcoholic fatty liver disease (NAFLD) is the most common form of liver disease and is characterized by fat accumulation in the liver. Hypercaloric diets generally increase hepatic fat accumulation, whereas hypocaloric diets decrease liver fat c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26b2c715a2813ca50f38590e9cb78d6e
Autor:
Magdalene K. Montgomery, Camille Devereux, Matthew J. Watt, Jacqueline Bayliss, Cheng Huang, David Roberts, Scott L. Townley, Dorit Samocha-Bonet, Ayenachew Bezawork-Geleta, Ruth C. R. Meex, Ralf B. Schittenhelm, Andrew Ryan, Gregory R. Steinberg, Trevor J. Biden, Luke A. Selth
Publikováno v:
Science Translational Medicine, 12(559):8048. American Association for the Advancement of Science
Intertissue communication is a fundamental feature of metabolic regulation, and the liver is central to this process. We have identified sparc-related modular calcium-binding protein 1 (SMOC1) as a glucose-responsive hepatokine and regulator of gluco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a783e3199ac1dd010bb5fa13902d4cfc
https://cris.maastrichtuniversity.nl/en/publications/4ff0da9e-6b61-4c36-9abf-fbb82385675e
https://cris.maastrichtuniversity.nl/en/publications/4ff0da9e-6b61-4c36-9abf-fbb82385675e
Autor:
Andrew L. Carey, Thomas Tsiloulis, Ruth C. R. Meex, Jacqueline Bayliss, Benedict J. Canny, Matthew J. Watt
Publikováno v:
International Journal of Obesity, 42(4), 721-727. Nature Publishing Group
BACKGROUND/OBJECTIVES: The phenomenon of adipocyte 'beiging' involves the conversion of non-classic brown adipocytes to brown-like adipose tissue with thermogenic, fat-burning properties, and this phenomenon has been shown in rodents to slow the prog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e089efab6406f08a7270dd6c7c540c7e
https://cris.maastrichtuniversity.nl/en/publications/6dddefa8-db9f-4b14-a219-c6a156d956a7
https://cris.maastrichtuniversity.nl/en/publications/6dddefa8-db9f-4b14-a219-c6a156d956a7
Autor:
Michael F. Keating, Kaushala S. Jayawardana, Elizabeth J. Tarling, Pengyi Yang, Benjamin L. Parker, Pauline Morand, Matthew J. Watt, Thomas Q. de Aguiar Vallim, Marcus M. Seldin, Matthew L. Miller, Richard T. Lee, Eser J. Zerenturk, Yingying Liu, Ruth C. R. Meex, Aldons J. Lusis, Brian G. Drew, Sarah C. Moody, David E. James, Calvin Pan, Natalie A. Mellett, Peter J. Meikle, Jacquelyn M. Weir, Ross Lazarus, Elise J. Needham, Anna C. Calkin, Bethan L. Clifford, Kang-Yu Peng
Publikováno v:
Nature, vol 567, iss 7747
Dysregulation of lipid homeostasis is a precipitating event in the pathogenesis and progression of hepatosteatosis and metabolic syndrome. These conditions are highly prevalent in developed societies and currently have limited options for diagnostic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b1bfa88bea79f16882362b6b6eb9b61
https://escholarship.org/uc/item/5090j5bq
https://escholarship.org/uc/item/5090j5bq
Publikováno v:
Nature reviews. Endocrinology. 15(5)
Evidence is accumulating that the gut microbiome is involved in the aetiology of obesity and obesity-related complications such as nonalcoholic fatty liver disease (NAFLD), insulin resistance and type 2 diabetes mellitus (T2DM). The gut microbiota is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c09b0009dd981b6eab5610f8ebf94977
https://pubmed.ncbi.nlm.nih.gov/30670819
https://pubmed.ncbi.nlm.nih.gov/30670819