Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Ruth Bolier"'
Autor:
Jacqueline Langedijk, Ruth Bolier, Dagmar Tolenaars, Lysbeth ten Bloemendaal, Suzanne Duijst, Dirk de Waart, Ulrich Beuers, Piter Bosma, Ronald Oude Elferink
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Pruritus is one of the most distressing symptoms in cholestatic patients. Plasma autotaxin (ATX) activity correlates with the severity of pruritus in cholestatic patients, but the pathophysiology is unclear. To study pruritus in mice, we mea
Externí odkaz:
https://doaj.org/article/8a91086451c548c488f3ed16188f6c17
Autor:
Ruth Bolier, Elsemieke S. de Vries, Albert Parés, Jeltje Helder, E. Marleen Kemper, Koos Zwinderman, Ronald P. Oude Elferink, Ulrich Beuers, the Netherlands Association for the Study of the Liver (NASL) Cholestatic Liver Diseases Study Group
Publikováno v:
Trials, Vol 18, Iss 1, Pp 1-9 (2017)
Abstract Background Pruritus (itch) is a frequent, burdensome and difficult-to-treat symptom in patients with cholestasis. Fibrates are currently under investigation for the treatment of primary biliary cholangitis in patients with a suboptimal respo
Externí odkaz:
https://doaj.org/article/bea8d41a13ee43b188786ddf2e53facc
Autor:
Willem-Jan Keune, Jens Hausmann, Ruth Bolier, Dagmar Tolenaars, Andreas Kremer, Tatjana Heidebrecht, Robbie P. Joosten, Manjula Sunkara, Andrew J. Morris, Elisa Matas-Rico, Wouter H. Moolenaar, Ronald P. Oude Elferink, Anastassis Perrakis
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
Autotaxin generates the bioactive lipid lysophosphatidic acid to regulate diverse biological processes. Here, the authors identify a role for bile salts as direct allosteric inhibitors of autotaxin activity, suggesting that steroids may function as r
Externí odkaz:
https://doaj.org/article/2ccdbeab88fd47eba8cb69bd11c92811
Autor:
Jacqueline Langedijk, Ruth Bolier, Yi-Té Lee, Ronald P.J. Oude Elferink, Catherine Williamson, Stan F.J. van de Graaf, Luciano Adorini, Amber Meurs, Ulrich Beuers, Dagmar Tolenaars
Publikováno v:
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE, 1867(11):166239. Elsevier
Background Autotaxin is an enzyme that converts lysophospholipid into lysophosphatidic acid (LPA), a highly potent signaling molecule through a range of LPA receptors. It is therefore important to investigate which factors play a role in regulating A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b38fc1c41728073d30ba677708de030
https://pure.amc.nl/en/publications/inhibition-of-autotaxin-by-bile-salts-and-bile-saltlike-molecules-increases-its-expression-by-feedback-regulation(9153cc2d-8e9d-4f4f-a81e-be7e90966f92).html
https://pure.amc.nl/en/publications/inhibition-of-autotaxin-by-bile-salts-and-bile-saltlike-molecules-increases-its-expression-by-feedback-regulation(9153cc2d-8e9d-4f4f-a81e-be7e90966f92).html
Publikováno v:
Journal of gerontological nursing, 42(12), 49-57. Slack Incorporated
How to Obtain Contact Hours by Reading this Article Instructions 1.4 contact hours will be awarded by Villanova University College of Nursing upon successful completion of this activity. A contact hour is a unit of measurement that denotes 60 minutes
Autor:
Karin C M J van Nieuwkerk, Elsemieke de Vries, Nahid Mostafavi, Karel J. van Erpecum, Frans van der Heide, Ruth Bolier, Marleen de Vree, Albert Parés, Jorn C Goet, Jef Verbeek, Ulrich Beuers, Ronald P.J. Oude Elferink, Jeltje Helder, Cyriel Y. Ponsioen, Joost P.H. Drenth, Henk R. van Buuren
Publikováno v:
Gastroenterology, 160, 3, pp. 734-743.e6
Gastroenterology, 160(3), 734-743.e6. W.B. Saunders
Gastroenterology, 160(3), 734-743.e6. W.B. Saunders Ltd
Gastroenterology, 160(3), 734-743.e6. W B SAUNDERS CO-ELSEVIER INC
Gastroenterology, 160(3), 734-+. Elsevier Saunders
Netherlands Association for the Study of the Liver-Cholestasis Working Group 2021, ' Fibrates for Itch (FITCH) in Fibrosing Cholangiopathies: A Double-Blind, Randomized, Placebo-Controlled Trial ', Gastroenterology, vol. 160, no. 3, pp. 734-743.e6 . https://doi.org/10.1053/j.gastro.2020.10.001
Gastroenterology, 160, 734-743.e6
Gastroenterology, 160(3), 734-743.e6. W.B. Saunders
Gastroenterology, 160(3), 734-743.e6. W.B. Saunders Ltd
Gastroenterology, 160(3), 734-743.e6. W B SAUNDERS CO-ELSEVIER INC
Gastroenterology, 160(3), 734-+. Elsevier Saunders
Netherlands Association for the Study of the Liver-Cholestasis Working Group 2021, ' Fibrates for Itch (FITCH) in Fibrosing Cholangiopathies: A Double-Blind, Randomized, Placebo-Controlled Trial ', Gastroenterology, vol. 160, no. 3, pp. 734-743.e6 . https://doi.org/10.1053/j.gastro.2020.10.001
Gastroenterology, 160, 734-743.e6
BACKGROUND AND AIMS: Pruritus may seriously impair quality of life in patients with cholestatic diseases such as primary or secondary sclerosing cholangitis (PSC, SSC) and primary biliary cholangitis (PBC). Pharmacologic strategies show limited effic
Autor:
Ruth Bolier, Ronald P.J. Oude Elferink, Albert Parés, Job Saris, Joanne Verheij, Dagmar Tolenaars, Ulrich Beuers, Andreas E. Kremer, Piter J. Bosma
Publikováno v:
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE, 1862(4), 696-704. Elsevier
Objective: Serum autotaxin (ATX) activity is significantly increased in cholestatic patients. Our study aimed to unravel the source(s) of ATX in cholestasis. Materials and methods: ATX activity and protein were measured in sera of healthy (n = 33) an
Autor:
Ulrich Beuers, Vinod S. Hegade, Stuart Kendrick, Ruth Bolier, Ronald P.J. Oude Elferink, David Jones
Publikováno v:
Frontline gastroenterology, 7(3), 158-166. BMJ Publishing Group
Pruritus (itch) is an important symptom of primary biliary cirrhosis (PBC), an archetypal cholestatic liver disease. Cholestatic pruritus can be a debilitating symptom causing significant deterioration in patients’ quality of life. Effective manage
Autor:
Dirk R. de Waart, Ruth Bolier, Suzanne Duijst, Coen C. Paulusma, Laura N. Bull, Johan K. Hiralall, Karina Sayuri Utsunomiya, Kam S. Ho-Mok, Ronald P.J. Oude Elferink, Jyoti Naik, Piter J. Bosma
Publikováno v:
Hepatology (Baltimore, Md.), 64(1), 161-174. John Wiley and Sons Ltd
Hepatology (Baltimore, Md.), vol 64, iss 1
Hepatology (Baltimore, Md.), vol 64, iss 1
UNLABELLED ATP11C is a homolog of ATP8B1, both of which catalyze the transport of phospholipids in biological membranes. Mutations in ATP8B1 cause progressive familial intrahepatic cholestasis type1 in humans, which is characterized by a canalicular
Autor:
Ruth Bolier, Diana Delgado, Bahar Niknejad, Elissa Kozlov, Charles Henderson, M. Carrington Reid, Corinna E. Löckenhoff
Publikováno v:
Niknejad, B, Bolier, R, Henderson, C R, Delgado, D, Kozlov, E, Löckenhoff, C E & Reid, M C 2018, ' Association between psychological interventions and chronic pain outcomes in older adults: A systematic review and meta-analysis ', JAMA Internal Medicine, vol. 178, no. 6, pp. 830-839 . https://doi.org/10.1001/jamainternmed.2018.0756
IMPORTANCE: Chronic noncancer pain (hereafter referred to as chronic pain) is common among older adults and managed frequently with pharmacotherapies that produce suboptimal outcomes. Psychological treatments are recommended, but little information i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b253114adb89f530750af7013ab04d1b
https://europepmc.org/articles/PMC6145761/
https://europepmc.org/articles/PMC6145761/