Membrane-bound TNF induces protective immune responses to M. bovis BCG infection: regulation of memTNF and TNF receptors comparing two memTNF molecules.

Autor: Maria L Olleros, Dominique Vesin, Ruth Bisig, Marie-Laure Santiago-Raber, Sonia Schuepbach-Mallepell, George Kollias, Olivier Gaide, Irene Garcia

Publikováno v: PLoS ONE, Vol 7, Iss 5, p e31469 (2012)

BACKGROUND: Several activities of the transmembrane form of TNF (memTNF) in immune responses to intracellular bacterial infection have been shown to be different from those exerted by soluble TNF. Evidence is based largely on studies in transgenic mi

Externí odkaz: https://doaj.org/article/3a89a2c3e5ca48ae8396446dcba442e5

The Ccr4-Not Complex Independently Controls both Msn2-Dependent Transcriptional Activation—via a Newly Identified Glc7/Bud14 Type I Protein Phosphatase Module—and TFIID Promoter Distribution

Autor: Joris Winderickx, Martine A. Collart, Katarina Petrovic, Johnny Roosen, Elisabetta Cameroni, Michel Werner, Ivo Pedruzzi, Claudio De Virgilio, Nicole James, Eve Lenssen, Ruth Bisig, Frédérique Dubouloz, Laurent Jean Marie Maillet

Publikováno v: Molecular and Cellular Biology, Vol. 25, No 1 (2005) pp. 488-98
Molecular and Cellular Biology
Molecular and Cellular Biology, 2005, 25, pp.488-498. ⟨10.1128/MCB.25.1.488-498.2005⟩
Molecular and Cellular Biology, American Society for Microbiology, 2005, 25, pp.488-498. ⟨10.1128/MCB.25.1.488-498.2005⟩

International audience; The Ccr4-Not complex is a conserved global regulator of gene expression, which serves as a regulatory platform that senses and/or transmits nutrient and stress signals to various downstream effectors. Presumed effectors of thi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9db4603a3319eb46b4040350e9091105
https://doi.org/10.1128/mcb.25.1.488-498.2005

In vitro inhibition of lipopolysaccharide and mycobacterium bovis bacillus Calmette Guerin-induced inflammatory cytokines and in vivo protection from D-galactosamine/LPS -mediated liver injury by the medicinal plant Sclerocarya birrea

Autor: Ruth Bisig, Sébastien Tauzin, Maria-Luisa Olleros, Télesphore Benoît Nguelefack, Théophile Dimo, Agathe L. Fotio, Etienne Dongo, Irene Garcia, Dominique Vesin, Pierre Kamtchouing

Publikováno v: International Journal of Immunopathology & Pharmacology, Vol. 23, No 1 (2010) pp. 61-72

Sclerocarya birrea is a medicinal plant used for the treatment of inflammatory- and bacterial-related diseases. The present study investigated in vitro and in vivo the effects of the stem bark methanol extract of S. birrea. Nitrite, TNF, IL-1β, IL-6

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a2c05f3309d2af5bc80b7a57ff9c4dc
https://archive-ouverte.unige.ch/unige:20462

Bacillus calmette-guerin infection in NADPH oxidase deficiency: defective mycobacterial sequestration and granuloma formation

Autor: Maria L. Olleros, Karl-Heinz Krause, Michela G. Schäppi, Tiina Kelkka, Xiaojuan Ma Mulone, Irene Garcia, Rikard Holmdahl, Dominique Vesin, Jean-Claude Pache, Julien Cachat, Ruth Bisig, Christine Deffert

Publikováno v: PLoS pathogens
PLOS PATHOGENS
PLoS Pathogens, Vol 10, Iss 9, p e1004325 (2014)
PLOSPATHOGENS
PLOS Pathogens, Vol. 10, No 9 (2014) P. e1004325
PLoS Pathogens

Patients with chronic granulomatous disease (CGD) lack generation of reactive oxygen species (ROS) through the phagocyte NADPH oxidase NOX2. CGD is an immune deficiency that leads to frequent infections with certain pathogens; this is well documented

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b270f8228e2dc5c052805d09b15f2cce

P018 Membrane-bound TNF induces protective cell-mediated immune responses to M. bovis BCG infection: Regulation of transmembrane TNF and TNF receptors mediating protection

Autor: Maria-Luisa Olleros, George Kollias, Dominique Vesin, Sonia Schuepbach-Mallepell, Irene Garcia, Marie-Laure Santiago-Raber, Olivier Gaide, Ruth Bisig

Publikováno v: Cytokine. 59:524

Introduction TNF is a pleiotropic cytokine associated with the development of human immunopathologies and involved in host defense mechanisms. TNF blockade has confirmed the crucial and non-redundant role of TNF in the control and resistance to tuber

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a537897ace2c3529b8a926bda480f35a
https://doi.org/10.1016/j.cyto.2012.06.101