Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Ruth Barak"'
Publikováno v:
Analytical Methods. 9:393-401
Although linked to a number of adverse health effects, studies of naphthalene are lacking in the exposure-relevant literature. This compound, a major by-product of the incomplete combustion of most organic materials (traffic vehicle exhaust, power ge
Publikováno v:
Archives of Environmental Contamination and Toxicology. 51:1-10
VX is one of the most toxic chemical warfare agents. Its low volatility and its persistence in the environment raise the issue of long-term exposure risks, either by inhalation or by transdermal penetration. Therefore, a topic of acute interest is th
Publikováno v:
Rapid Communications in Mass Spectrometry. 15:2110-2116
Analysis by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOFMS) was applied for the characterization of Bacillus anthracis spore biomarkers. B. anthracis spores were extracted under a simple procedure, followed
Autor:
M Leitner, Avigdor Shafferman, Zeev Altboum, I. Mendelson, S. Cohen, Itzhak Inbar, Eytan Elhanany, Yehoshua Gozes, David Kobiler, Morly Fisher, Tamar Bino, Chanoch Kronman, Baruch Velan, Ruth Barak, H. Rosenberg
Publikováno v:
Infection and Immunity. 68:4549-4558
The etiological agent of anthrax disease in animals and humans is the spore-forming bacterium Bacillus anthracis. The major factors of virulence of B. anthracis are located on two plasmids, pXO1 and pXO2. pXO2 encodes a poly-d-glutamic acid capsule (
Autor:
Yoffi Segall, Hendrik P. Benschop, Avigdor Shafferman, Arie Ordentlich, Leo P. A. De Jong, Baruch Velan, Meir Fischer, Ruth Barak, Dov Barak
Publikováno v:
FEBS Letters, 3, 407, 347-352
While non-reactivability of cholinesterases from their phosphyl conjugates (aging) is attributed to an unimolecular process involving loss of alkyl group from the phosphyl moiety, no conclusive evidence is available that this is the only reaction pat
Autor:
Kenneth L. Busch, Richard Dunphy, David J. Burinsky, Gabriel Amitai, Adam Vincze, Peter Bel, Gary J. Kunkel, Ruth Barak
Publikováno v:
Journal of Mass Spectrometry. 30:282-289
Positive-ion mass spectra of diquaternary pyridinium oxime salts were measured using fast atom bombardment and liquid secondary ion mass spectrometry in different laboratories to establish both the characteristic behavior and the spectral variability
Autor:
Dana Kaplan, Eytan Elhanany, Arie Ordentlich, Avigdor Shafferman, Ruth Barak, O Dgany, Yoffi Segall, Baruch Velan
Publikováno v:
Cholinergic Mechanisms
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::97614e788a9685d93d5c8585fc9f31b7
https://doi.org/10.3109/9780203493878-93
https://doi.org/10.3109/9780203493878-93
Autor:
Baruch Velan, Dana Kaplan, Eytan Elhanany, Yoffi Segall, Arie Ordentlich, Or Dgany, Ruth Barak, Avigdor Shafferman
Publikováno v:
Chemical research in toxicology. 14(7)
Understanding reaction pathways of phosphylation, reactivation, and "aging" of AChE with toxic organophosphate compounds is both a biochemical and a pharmacological challenge. Here we describe experiments which allowed to resolve some of the less wel
Evidence for P-N bond scission in phosphoroamidate nerve agent adducts of human acetylcholinesterase
Autor:
Dana M. Mizrahi, Dana Kaplan, Arie Ordentlich, Avigdor Shafferman, Baruch Velan, Dov Barak, Ruth Barak, Yoffi Segall, Chanoch Kronman
Publikováno v:
Biochemistry. 39(5)
Acetylcholinesterases (AChEs) form conjugates with certain highly toxic organophosphorus (OP) agents that become gradually resistant to reactivation. This phenomenon termed "aging" is a major factor limiting the effectiveness of therapy in certain ca
Autor:
Baruch Velan, Arie Ordentlich, H.P. Benschop, Avigdor Shafferman, Yoffi Segall, Naomi Ariel, C. Kronman, L. P. A. De Jong, Dov Barak, Ruth Barak
Publikováno v:
Biochemistry, 10, 38, 3055-3066
The stereoselectivity of the phosphonylation reaction and the effects of adduct configuration on the aging process were examined for human acetylcholinesterase (HuAChE) and its selected active center mutants, using the four stereomers of 1,2,2-trimet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5dcd685c6fed21031cfc7b8b73fd6c4b
http://resolver.tudelft.nl/uuid:77789a1e-3506-443e-b1e8-d1552f27a109
http://resolver.tudelft.nl/uuid:77789a1e-3506-443e-b1e8-d1552f27a109