Zobrazeno 1 - 10
of 113
pro vyhledávání: '"Ruth Ann Luna"'
Autor:
Santosh Thapa, Ruth Ann Luna, Bruno P. Chumpitazi, Numan Oezguen, Susan M. Abdel‐Rahman, Uttam Garg, Salma Musaad, James Versalovic, Gregory L. Kearns, Robert J. Shulman
Publikováno v:
Clinical and Translational Science, Vol 15, Iss 4, Pp 1036-1049 (2022)
Abstract Peppermint oil (PMO) is effective in the treatment of functional abdominal pain disorders, but its mechanism of action is unclear. Evidence suggests PMO has microbicidal activity. We investigated the effect of three different doses of PMO on
Externí odkaz:
https://doaj.org/article/ef014f884ec24924b5923f470789c090
Autor:
Thomas D. Horvath, Faith D. Ihekweazu, Sigmund J. Haidacher, Wenly Ruan, Kristen A. Engevik, Robert Fultz, Kathleen M. Hoch, Ruth Ann Luna, Numan Oezguen, Jennifer K. Spinler, Anthony M. Haag, James Versalovic, Melinda A. Engevik
Publikováno v:
iScience, Vol 25, Iss 5, Pp 104158- (2022)
Summary: Gut microbes can synthesize multiple neuro-active metabolites. We profiled neuro-active compounds produced by the gut commensal Bacteroides ovatus in vitro and in vivo by LC-MS/MS. We found that B. ovatus generates acetic acid, propionic aci
Externí odkaz:
https://doaj.org/article/9265eb55b5e3455eacfd6e2f6f4ffdf8
Autor:
Prapaporn Boonma, Jordan M. Shapiro, Emily B. Hollister, Shyam Badu, Qinglong Wu, Erica M. Weidler, Bincy P. Abraham, Sridevi Devaraj, Ruth Ann Luna, James Versalovic, Margaret M. Heitkemper, Tor C. Savidge, Robert J. Shulman
Publikováno v:
Frontiers in Pain Research, Vol 2 (2021)
Background: Little is known regarding the clinical impact of treatment and treatment duration of probiotic VSL#3 on gut and microbiome function in irritable bowel syndrome (IBS). As part of a safety trial, we assessed the effect of VSL#3 treatment du
Externí odkaz:
https://doaj.org/article/b17dc45b76f14cabbd64631563111740
Autor:
Andrea C. Blackman, Santosh Thapa, Alamelu Venkatachalam, Thomas D. Horvath, Jessica K. Runge, Sigmund J. Haidacher, Kathleen M. Hoch, Anthony M. Haag, Ruth Ann Luna, Aikaterini Anagnostou
Publikováno v:
Children, Vol 9, Iss 8, p 1192 (2022)
Background: Peanut oral immunotherapy has emerged as a novel, active management approach for peanut-allergic sufferers, but limited data exist currently on the role of the microbiome in successful desensitization. Objective: We examined the oral and
Externí odkaz:
https://doaj.org/article/5cc622f0176e407280dfa3934dfe6efe
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
Externí odkaz:
https://doaj.org/article/8f7dcccc725f409ba593e924f8b09ba7
Autor:
Santosh Thapa, Alamelu Venkatachalam, Nabeel Khan, Mohammed Naqvi, Miriam Balderas, Jessica K Runge, Anthony Haag, Kathleen M Hoch, Daniel G Glaze, Ruth Ann Luna, Kathleen J Motil
Publikováno v:
PLoS ONE, Vol 16, Iss 5, p e0251231 (2021)
BackgroundGastrointestinal problems affect the health and quality of life of individuals with Rett syndrome (RTT) and pose a medical hardship for their caregivers. We hypothesized that the variability in the RTT phenotype contributes to the dysbiosis
Externí odkaz:
https://doaj.org/article/232372eb776e44c49e47fc33ba90da56
Autor:
Jourdan A. Andersson, Alex G. Peniche, Cristi L. Galindo, Prapaporn Boonma, Jian Sha, Ruth Ann Luna, Tor C. Savidge, Ashok K. Chopra, Sara M. Dann
Publikováno v:
mBio, Vol 11, Iss 2 (2020)
ABSTRACT Frequent and excessive use of antibiotics primes patients to Clostridioides difficile infection (CDI), which leads to fatal pseudomembranous colitis, with limited treatment options. In earlier reports, we used a drug repurposing strategy and
Externí odkaz:
https://doaj.org/article/5e714ff007e247f187ae4679e2689807
Autor:
Mohan Pammi, Santosh Thapa, Miriam Balderas, Jessica K Runge, Alamelu Venkatachalam, Ruth Ann Luna
Publikováno v:
PLoS ONE, Vol 15, Iss 1, p e0227967 (2020)
Neonates are at high risk for central line associated bloodstream infections (CLABSI). Biofilm formation is universal on indwelling catheters but why some biofilms seed the bloodstream to cause CLABSI is not clearly understood. With the objective to
Externí odkaz:
https://doaj.org/article/72225552e01540c0a6c1fbcd7d9ddac7
Autor:
Jennifer S. Labus, Emily B. Hollister, Jonathan Jacobs, Kyleigh Kirbach, Numan Oezguen, Arpana Gupta, Jonathan Acosta, Ruth Ann Luna, Kjersti Aagaard, James Versalovic, Tor Savidge, Elaine Hsiao, Kirsten Tillisch, Emeran A. Mayer
Publikováno v:
Microbiome, Vol 5, Iss 1, Pp 1-17 (2017)
Abstract Background Preclinical and clinical evidence supports the concept of bidirectional brain-gut microbiome interactions. We aimed to determine if subgroups of irritable bowel syndrome (IBS) subjects can be identified based on differences in gut
Externí odkaz:
https://doaj.org/article/8a43c16877064a318a257fba038eff32
Autor:
Ruth Ann Luna, Numan Oezguen, Miriam Balderas, Alamelu Venkatachalam, Jessica K. Runge, James Versalovic, Jeremy Veenstra-VanderWeele, George M. Anderson, Tor Savidge, Kent C. Williams
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 3, Iss 2, Pp 218-230 (2017)
Background & Aims: Emerging data on the gut microbiome in autism spectrum disorder (ASD) suggest that altered hostâmicrobe interactions may contribute to disease symptoms. Although gut microbial communities in children with ASD are reported to diffe
Externí odkaz:
https://doaj.org/article/8a11fdfbb3114208b58efc8ab6e5a9fd