Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Ruth A Henderson"'
Autor:
Sally D. O'Neal, Ruth E. Henderson, Geoffrey M. Groenendale, Daniel P. Groenendale, Ann E. George, Matt J. Hengel, Douglas B. Walsh
Publikováno v:
Journal of the American Society of Brewing Chemists. 74:53-56
This study was conducted to determine whether beers produced with late (i.e., after kettle-boil) additions of hops Humulus lupulus cultivars Cascade or Chinook (either dry hopped with whole or pell...
Autor:
Richard Eric Mewshaw, James C. Keith, Eric S. Manas, Cuijian Yang, Ruth A. Henderson, Heather A. Harris, Richard James Edsall, Zhang B. Xu
Publikováno v:
Journal of Medicinal Chemistry. 48:3953-3979
The 2-phenylnaphthalene scaffold was explored as a simplified version of genistein in order to identify ER selective ligands. With the aid of docking studies, positions 1, 4, and 8 of the 2-phenylnaphthalene template were predicted to be the most pot
Autor:
Z.B. Xu, Chris P. Miller, H.A. Harris, Collini, Robert Emmett Mcdevitt, E.S. Manas, T. Dinh, J.C. Keith, Michael S. Malamas, Iwan Gunawan, Ruth A. Henderson
Publikováno v:
Journal of Medicinal Chemistry. 47:5021-5040
New diphenolic azoles as highly selective estrogen receptor-beta agonists are reported. The more potent and selective analogues of these series have comparable binding affinities for ERbeta as the natural ligand 17beta-estradiol but are >100-fold sel
Autor:
Moran Ra, Yardley Jp, C R Lyttle, Magid Abou-Gharbia, Ruth A. Henderson, Lee M. Greenberger, Collini, Chris P. Miller, Marzolf Jt, Bender Rh, Heather A. Harris, Tran Bd, B S Komm, Yogendra P. Kharode, Rayomand J Unwalla
Publikováno v:
Journal of Medicinal Chemistry. 44:1654-1657
Publikováno v:
Endocrinology. 142:645-652
Estrogen receptor-beta (ERbeta) is a recently discovered member of the steroid hormone superfamily. Because its distribution is distinct from that of the classical estrogen receptor, and it is expressed in several nonclassical estrogen target tissues
Autor:
Nancy Newton, Ruth E Henderson
Publikováno v:
Ambulatory Child Health. 6:247-252
Objectives To assess the effectiveness of a universal school entry hearing screen (sweep audiogram). Methods Information was obtained from the audiology service and Community Child Health records, if available, for children who had an abnormality det
Publikováno v:
The Journal of endocrinology. 185(2)
Estrogens have been shown to modulate disease activity in experimental autoimmune encephalomyelitis (EAE), the mouse model for multiple sclerosis. Consistent with these findings, the severity of disease is reduced in pregnant women with multiple scle
Autor:
Michael D. Collini, David H. Kaufman, Chris P. Miller, Heather A. Harris, Rayomand J. Unwalla, Zhang B. Xu, Ruth A. Henderson, Eric S. Manas
Publikováno v:
ChemInform. 36
A series of 2-(4-hydroxy-phenyl)-benzofuran-5-ols with relatively lipophilic groups in the 7-position of the benzofuran was prepared and the affinity and selectivity for ER beta was measured. Many of the analogues were found to be potent and selectiv
Publikováno v:
Immunology letters. 97(1)
Estrogens have been shown to modulate immune responses. Several studies have demonstrated the capacity of T cells, B cells, and monocytes to respond to estrogens and estrogen receptor (ER) expression in these cell types has been reported. However, li
Autor:
Yelena Leathurby, Ruth A. Henderson, Yogendra P. Kharode, Michael S. Malamas, James Marzolf, Richard C. Winneker, Yuan Zhu, Barry S. Komm, Richard Eric Mewshaw, Chris P. Miller, Heather A. Harris, Donald E. Frail, Leo M. Albert, James C. Keith
Publikováno v:
Endocrinology. 144(10)
The discovery of a second estrogen receptor (ER), called ERβ, in 1996 sparked intense interest within the scientific community to discover its role in mediating estrogen action. However, despite more than 6 yr of research into the function of this r