Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Ruth, Navon"'
Autor:
Esther Osher, Yossi Anis, Ruth Singer-Shapiro, Nataly Urshanski, Tamar Unger, Shira Albeck, Oren Bogin, Gary Weisinger, Fortune Kohen, Avi Valevski, Aviva Fattal-Valevski, Liora Sagi, Michal Weitman, Yulia Shenberger, Nadav Sagiv, Ruth Navon, Meir Wilchek, Naftali Stern
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 32, Iss 3, Pp 101300- (2024)
Tay-Sachs (TS) disease is a neurodegenerative disease resulting from mutations in the gene encoding the α-subunit (HEXA) of lysosomal β-hexosaminidase A (HexA). We report that (1) recombinant HEXA alone increased HexA activity and decreased GM2 con
Externí odkaz:
https://doaj.org/article/b46b268575554f2eb291b7d475a23c94
Publikováno v:
Neurobiology of Disease, Vol 55, Iss , Pp 1-10 (2013)
Schizophrenia is a common neuropsychiatric disorder that has a strong genetic component. MicroRNAs (miRNAs) have been implicated in neurodevelopmental and psychiatric disorders including schizophrenia, as indicated by their dysregulation in post-mort
Externí odkaz:
https://doaj.org/article/4f7a08e058f64978ba93f0cd345b5355
Publikováno v:
Neurobiology of Disease, Vol 55, Iss, Pp 1-10 (2013)
Schizophrenia is a common neuropsychiatric disorder that has a strong genetic component. MicroRNAs (miRNAs) have been implicated in neurodevelopmental and psychiatric disorders including schizophrenia, as indicated by their dysregulation in post-mort
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cff3c4b9e16962051b671578a8a9613
http://www.sciencedirect.com/science/article/pii/S0969996113000995
http://www.sciencedirect.com/science/article/pii/S0969996113000995
Publikováno v:
Human Molecular Genetics. 21:311-321
Schizophrenia and bipolar disorder (BPD) are common neurodevelopmental disorders, characterized by various life-crippling symptoms and high suicide rates. Multiple studies support a strong genetic involvement in the etiology of these disorders, altho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ec822715bd2c3b8bb92eb8528895897
https://doi.org/10.1093/hmg/ddr461
https://doi.org/10.1093/hmg/ddr461
Autor:
Leonardo Tondo, Gianfranco Floris, David St Clair, Robert Kerwin, Gilad Silberberg, David A. Collier, Janet Munro, Gerome Breen, Ruth Navon, Anat Levit
Publikováno v:
Pharmacogenetics and Genomics. 18:403-412
OBJECTIVES Multiple reports have implicated chromosomal region 22q13.1 in both schizophrenia and bipolar disorder. The calcium channel gamma-2 subunit gene (cacng2, Stargazin) located on 22q13.1 was recently reported to be associated with schizophren
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13ca2a95703613840ea16dc3f2a2c5d7
https://doi.org/10.1097/fpc.0b013e3282f974ca
https://doi.org/10.1097/fpc.0b013e3282f974ca
Autor:
Julien Mendlewicz, Jurgen Del-Favero, Stephan Claes, Daniel Souery, Dirk Goossens, C. Van Broeckhoven, Maaike Alaerts, T Venken, Ruth Navon, S Sluijs
Publikováno v:
Molecular psychiatry
Europe PubMed Central
Europe PubMed Central
We report the results of a 10 cM density genome-wide scan and further fine mapping of three chromosomal candidate regions in 10 Belgian multigenerational families with bipolar (BP) disorder. This two-stage approach revealed significant evidence for l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07b67977efc4a5cc2e284425a3a6ea3f
https://doi.org/10.1038/sj.mp.4002039
https://doi.org/10.1038/sj.mp.4002039
Autor:
Michal Bronstein, Ariel Darvasi, Ruth Navon, Avraham Weizman, Benjamin Yakir, Mao-Liang Chen, Chia-Hsiang Chen, Anat Levit, Sagiv Shifman
Publikováno v:
Human Genetics. 120:160-170
Several lines of evidence have established the presence of an association between a 3-Mb deletion in chromosome 22q11 and schizophrenia. In this paper we present a complete high-density SNP scan of this segment using DNA pools, and demonstrate signif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88428ab3baa6147ab28990824efa2108
https://doi.org/10.1007/s00439-006-0195-0
https://doi.org/10.1007/s00439-006-0195-0
Autor:
I. Murad, M. Dobrusin, Alina Cholostoy, U. Bening‐Abu‐Shach, Michael Korostishevsky, I. Bannoura, Wolfgang Maier, Ruth Navon, Robert H. Belmaker, M. Kaganovich, Richard P. Ebstein, Ilana Kremer, Marcella Rietschel, M. Muhaheed
Publikováno v:
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. :91-95
Association of the G72/G30 locus with schizophrenia was recently reported in French Canadian, Russian, and Ashkenazi populations using case-control studies. In the present study we hypothesize the existence of a G72/G30 risk allele over-transmitted t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4514e1dce1bfe101e923c5c132bc314f
https://doi.org/10.1002/ajmg.b.30212
https://doi.org/10.1002/ajmg.b.30212
Autor:
Alina Cholostoy, Maya Ashkenazi, Yael Ratner, Edna Ben-Asher, Miryam Kaganovich, Michael S. Ritsner, Michael Korostishevsky, Ruth Navon, Ullrike Bening-Abu-Shach, Jeanne Bernstein, Dvir Dahary, Doron Lancet
Publikováno v:
Biological Psychiatry. 56:169-176
Background The genes G72/G30 were recently implicated in schizophrenia in both Canadian and Russian populations. We hypothesized that 1) polymorphic changes in this gene region might be associated with schizophrenia in the Ashkenazi Jewish population
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4ea36ebcb2d64e0470c9b9c64b721fe
https://doi.org/10.1016/j.biopsych.2004.04.006
https://doi.org/10.1016/j.biopsych.2004.04.006
Autor:
Evan Reid, P. Nisipeanu, Aziz Mazarib, David Withers, Sergiu C. Blumen, Saif Abu-Mouch, Michael Kahana, Rifka Inzelberg, Simon Bevan, R.L. Carasso, Ruth Navon, David Negus, Ahmad Mahamid, Hanoch Slor
Publikováno v:
Annals of Neurology. 54:796-803
We updated the clinical features of a consanguineous Arab Israeli family, in which four of seven children were affected by spastic paraplegia complicated by skin pigmentary abnormalities. A genomewide linkage screen performed for the family identifie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd34edb478edee2bcf7c9f69585e64bd
https://doi.org/10.1002/ana.10768
https://doi.org/10.1002/ana.10768