Zobrazeno 1 - 10
of 83
pro vyhledávání: '"Ruth, Navon"'
Autor:
Esther Osher, Yossi Anis, Ruth Singer-Shapiro, Nataly Urshanski, Tamar Unger, Shira Albeck, Oren Bogin, Gary Weisinger, Fortune Kohen, Avi Valevski, Aviva Fattal-Valevski, Liora Sagi, Michal Weitman, Yulia Shenberger, Nadav Sagiv, Ruth Navon, Meir Wilchek, Naftali Stern
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 32, Iss 3, Pp 101300- (2024)
Tay-Sachs (TS) disease is a neurodegenerative disease resulting from mutations in the gene encoding the α-subunit (HEXA) of lysosomal β-hexosaminidase A (HexA). We report that (1) recombinant HEXA alone increased HexA activity and decreased GM2 con
Externí odkaz:
https://doaj.org/article/b46b268575554f2eb291b7d475a23c94
Publikováno v:
Neurobiology of Disease, Vol 55, Iss , Pp 1-10 (2013)
Schizophrenia is a common neuropsychiatric disorder that has a strong genetic component. MicroRNAs (miRNAs) have been implicated in neurodevelopmental and psychiatric disorders including schizophrenia, as indicated by their dysregulation in post-mort
Externí odkaz:
https://doaj.org/article/4f7a08e058f64978ba93f0cd345b5355
Publikováno v:
Neurobiology of Disease, Vol 55, Iss, Pp 1-10 (2013)
Schizophrenia is a common neuropsychiatric disorder that has a strong genetic component. MicroRNAs (miRNAs) have been implicated in neurodevelopmental and psychiatric disorders including schizophrenia, as indicated by their dysregulation in post-mort
Publikováno v:
Human Molecular Genetics. 21:311-321
Schizophrenia and bipolar disorder (BPD) are common neurodevelopmental disorders, characterized by various life-crippling symptoms and high suicide rates. Multiple studies support a strong genetic involvement in the etiology of these disorders, altho
Autor:
Leonardo Tondo, Gianfranco Floris, David St Clair, Robert Kerwin, Gilad Silberberg, David A. Collier, Janet Munro, Gerome Breen, Ruth Navon, Anat Levit
Publikováno v:
Pharmacogenetics and Genomics. 18:403-412
OBJECTIVES Multiple reports have implicated chromosomal region 22q13.1 in both schizophrenia and bipolar disorder. The calcium channel gamma-2 subunit gene (cacng2, Stargazin) located on 22q13.1 was recently reported to be associated with schizophren
Autor:
Julien Mendlewicz, Jurgen Del-Favero, Stephan Claes, Daniel Souery, Dirk Goossens, C. Van Broeckhoven, Maaike Alaerts, T Venken, Ruth Navon, S Sluijs
Publikováno v:
Molecular psychiatry
Europe PubMed Central
Europe PubMed Central
We report the results of a 10 cM density genome-wide scan and further fine mapping of three chromosomal candidate regions in 10 Belgian multigenerational families with bipolar (BP) disorder. This two-stage approach revealed significant evidence for l
Autor:
Michal Bronstein, Ariel Darvasi, Ruth Navon, Avraham Weizman, Benjamin Yakir, Mao-Liang Chen, Chia-Hsiang Chen, Anat Levit, Sagiv Shifman
Publikováno v:
Human Genetics. 120:160-170
Several lines of evidence have established the presence of an association between a 3-Mb deletion in chromosome 22q11 and schizophrenia. In this paper we present a complete high-density SNP scan of this segment using DNA pools, and demonstrate signif
Autor:
I. Murad, M. Dobrusin, Alina Cholostoy, U. Bening‐Abu‐Shach, Michael Korostishevsky, I. Bannoura, Wolfgang Maier, Ruth Navon, Robert H. Belmaker, M. Kaganovich, Richard P. Ebstein, Ilana Kremer, Marcella Rietschel, M. Muhaheed
Publikováno v:
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. :91-95
Association of the G72/G30 locus with schizophrenia was recently reported in French Canadian, Russian, and Ashkenazi populations using case-control studies. In the present study we hypothesize the existence of a G72/G30 risk allele over-transmitted t
Autor:
Alina Cholostoy, Maya Ashkenazi, Yael Ratner, Edna Ben-Asher, Miryam Kaganovich, Michael S. Ritsner, Michael Korostishevsky, Ruth Navon, Ullrike Bening-Abu-Shach, Jeanne Bernstein, Dvir Dahary, Doron Lancet
Publikováno v:
Biological Psychiatry. 56:169-176
Background The genes G72/G30 were recently implicated in schizophrenia in both Canadian and Russian populations. We hypothesized that 1) polymorphic changes in this gene region might be associated with schizophrenia in the Ashkenazi Jewish population
Autor:
Evan Reid, P. Nisipeanu, Aziz Mazarib, David Withers, Sergiu C. Blumen, Saif Abu-Mouch, Michael Kahana, Rifka Inzelberg, Simon Bevan, R.L. Carasso, Ruth Navon, David Negus, Ahmad Mahamid, Hanoch Slor
Publikováno v:
Annals of Neurology. 54:796-803
We updated the clinical features of a consanguineous Arab Israeli family, in which four of seven children were affected by spastic paraplegia complicated by skin pigmentary abnormalities. A genomewide linkage screen performed for the family identifie