Nonlinear Z‐score modeling for improved detection of cognitive abnormality

Autor: John Kornak, Julie Fields, Walter Kremers, Sara Farmer, Hilary W. Heuer, Leah Forsberg, Danielle Brushaber, Amy Rindels, Hiroko Dodge, Sandra Weintraub, Lilah Besser, Brian Appleby, Yvette Bordelon, Jessica Bove, Patrick Brannelly, Christina Caso, Giovanni Coppola, Reilly Dever, Christina Dheel, Bradford Dickerson, Susan Dickinson, Sophia Dominguez, Kimiko Domoto‐Reilly, Kelley Faber, Jessica Ferrall, Ann Fishman, Jamie Fong, Tatiana Foroud, Ralitza Gavrilova, Deb Gearhart, Behnaz Ghazanfari, Nupur Ghoshal, Jill Goldman, Jonathan Graff‐Radford, Neill Graff‐Radford, Ian M. Grant, Murray Grossman, Dana Haley, John Hsiao, Robin Hsiung, Edward D. Huey, David Irwin, David Jones, Lynne Jones, Kejal Kantarci, Anna Karydas, Daniel Kaufer, Diana Kerwin, David Knopman, Ruth Kraft, Joel Kramer, Walter Kukull, Maria Lapid, Irene Litvan, Peter Ljubenkov, Diane Lucente, Codrin Lungu, Ian Mackenzie, Miranda Maldonado, Masood Manoochehri, Scott McGinnis, Emily McKinley, Mario Mendez, Bruce Miller, Namita Multani, Chiadi Onyike, Jaya Padmanabhan, Alexander Pantelyat, Rodney Pearlman, Len Petrucelli, Madeline Potter, Rosa Rademakers, Eliana Marisa Ramos, Katherine Rankin, Katya Rascovsky, Erik D. Roberson, Emily Rogalski‐Miller, Pheth Sengdy, Les Shaw, Adam M. Staffaroni, Margaret Sutherland, Jeremy Syrjanen, Carmela Tartaglia, Nadine Tatton, Joanne Taylor, Arthur Toga, John Trojanowski, Ping Wang, Bonnie Wong, Zbigniew Wszolek, Brad Boeve, Adam Boxer, Howard Rosen, ARTFL/LEFFTDS Consortium

Publikováno v: Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 11, Iss 1, Pp 797-808 (2019)

Abstract Introduction Conventional Z‐scores are generated by subtracting the mean and dividing by the standard deviation. More recent methods linearly correct for age, sex, and education, so that these “adjusted” Z‐scores better represent whe

Externí odkaz: https://doaj.org/article/a6622d356e19452690bcb069ec439d27

Frontal lobe 1H MR spectroscopy in asymptomatic and symptomatic MAPT mutation carriers

Autor: Qin Chen, Christina Dheel, Jonathan Graff-Radford, Howie Rosen, Neill R. Graff-Radford, Leah K. Forsberg, Adam L. Boxer, David S. Knopman, Dana Haley, Debra Gearhart, Jeffrey L. Gunter, Zbigniew K. Wszolek, Ruth Kraft, Maria I. Lapid, Jeremy Syrjanen, David R. Jones, Ralitza H. Gavrilova, Timothy G. Lesnick, Kejal Kantarci, Julie A. Fields, Nirubol Tosakulwong, Bradley F. Boeve, Rosa Rademakers, Danielle Brushaber

Publikováno v: Neurology. 93:e758-e765

ObjectiveTo determine the frontal lobe proton magnetic resonance spectroscopy (1H MRS) abnormalities in asymptomatic and symptomatic carriers of microtubule-associated protein tau (MAPT) mutations.MethodsWe recruited patients with MAPT mutations from

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::59940e27eb8e50e7d64c75bf2c2ac91b
https://doi.org/10.1212/wnl.0000000000007961

Comparison of sporadic and familial behavioral variant frontotemporal dementia (FTD) in a North American cohort

Autor: Jessica Ferrall, Julie A. Fields, Edward D. Huey, Anna Karydas, Len Petrucelli, John Kornak, Kejal Kantarci, Pei Ning Wang, G-Y Hsiung, Dana Haley, Artfl, Emily C. McKinley, Erik D. Roberson, Masood Manoochehri, Maria Carmela Tartaglia, Brian S. Appleby, Zbigniew Wszolek, Walter K. Kremers, Amy Wolf, Diana R. Kerwin, Bradford C. Dickerson, Murray Grossman, Bruce L. Miller, Ian Grant, Ann Fishman, Jill Goldman, Leah K. Forsberg, Miranda Maldonado, Howard J. Rosen, Ian R. Mackenzie, Patrick Brannelly, Joel H. Kramer, Eliana Marisa Ramos, Behnaz Ghazanfari, Lefftds consortia, Katherine P. Rankin, Katya Rascovsky, Mario F. Mendez, Yvette Bordelon, Leslie M. Shaw, Arthur W. Toga, Chiadikaobi U. Onyike, Irene Litvan, Scott M. McGinnis, Peter A. Ljubenkov, Hilary W. Heuer, Rodney Pearlman, Walter A. Kukull, Nadine Tatton, Adam L. Boxer, Ruth Kraft, David T.W. Jones, Joanne Taylor, Giovanni Coppola, Tatiana Foroud, Debra Gearhart, Jonathan Graff-Radford, B. F. Boeve, Alexander Pantelyat, Danielle Brushaber, Daniel I. Kaufer, Rosa Rademakers, Madeline Potter, Kelly Faber, John Q. Trojanowski, Jamie Fong, Christina Caso, Emily Rogalski, Nupur Ghoshal, Neill Graff-Radford, Jeremy Syrjanen, Susan Dickinson, Pheth Sengdy, Jessica Bove, Sandra Weintraub, Bonnie Wong, Kimiko Domoto-Reilly, David S. Knopman, David J. Irwin

Publikováno v: Alzheimers Dement

Author(s): Heuer, Hilary W; Wang, P; Rascovsky, K; Wolf, A; Appleby, B; Bove, J; Bordelon, Y; Brannelly, P; Brushaber, DE; Caso, C; Coppola, G; Dickerson, B; Dickinson, S; Domoto-Reilly, K; Faber, K; Ferrall, J; Fields, J; Fishman, A; Fong, J; Foroud

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8880125937f4973bdacfaffcace77a62
https://pubmed.ncbi.nlm.nih.gov/31914226

The longitudinal evaluation of familial frontotemporal dementia subjects protocol : framework and methodology

Autor: Katherine P. Rankin, Diane Lucente, Debra Gearhart, David J. Irwin, John Kornak, Jennifer G. Goldman, Tatiana Foroud, Ging-Yuek Robin Hsiung, Jessica Bove, Rosa Rademakers, Bradley F. Boeve, Jonathan Graff-Radford, Howard J. Rosen, Sandra Weintraub, Danielle Brushaber, Walter K. Kremers, Bonnie Wong, John Q. Trojanowski, Arthur W. Toga, Julie A. Fields, Leah K. Forsberg, Dana Haley, Nupur Ghoshal, Bradford C. Dickerson, Len Petrucelli, Madeline Potter, Murray Grossman, Anna Karydas, Walter A. Kukull, Joel H. Kramer, Kejal Kantarci, Rielly Dever, Eliana Marisa Ramos, David S. Knopman, Susan Dickinson, Les Shaw, Pheth Sengdy, Jamie Fong, Neill Graff-Radford, Adam L. Boxer, David T.W. Jones, Hilary W. Heuer, Scott M. McGinnis, Rodney Pearlman, Jeremy Syrjanen, Nadine Tatton, Joanne Taylor, Giovanni Coppola, Katya Rascovsky, Bruce L. Miller, Masood Manoochehri, Christina Dheel, Edward D. Huey, Zbigniew Wszolek, Ruth Kraft, Maria I. Lapid, Lynne Jones, Kelley Faber, Ralitza H. Gavrilova, Ian R. Mackenzie, Patrick Brannelly

Publikováno v: Alzheimer's & dementia
Alzheimers Dement

Introduction It is important to establish the natural history of familial frontotemporal lobar degeneration (f-FTLD) and provide clinical and biomarker data for planning these studies, particularly in the asymptomatic phase. Methods The Longitudinal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5b07cd7194976ebe12240d532b302eb
https://repository.uantwerpen.be/docstore/d:irua:5312

Use of the CDR® plus NACC FTLD in mild FTLD: Data from the ARTFL/LEFFTDS consortium

Autor: Christina Dheel, Kimiko Domoto-Reilly, Diane Lucente, Sandra Weintraub, Jonathan Graff-Radford, Howie Rosen, Tatiana Foroud, Christina Caso, Robin Hsiung, Emily Rogalski, Ruth Kraft, Walter A. Kukull, Emily C. McKinley, Yvette Bordelon, Sophia Dominguez, Codrin Lungu, Arthur W. Toga, Leslie M. Shaw, Erik D. Roberson, Maria Carmela Tartaglia, John Q. Trojanowski, Patrick Brannelly, Zbigniew K. Wszolek, Bonnie Wong, Jessica Bove, Julie A. Fields, Masood Manoochehri, Ping Wang, Neill R. Graff-Radford, Anna Karydas, Leonard Petrucelli, Irene Litvan, Brian S. Appleby, Madeline Potter, Kejal Kantarci, Ian Grant, Adam L. Boxer, David T.W. Jones, Ann Fishman, Jamie Fong, Leah K. Forsberg, Bruce L. Miller, Edward D. Huey, Susan Dickinson, Pheth Sengdy, Katya Rascovsky, Walter K. Kremers, Bradford C. Dickerson, Chiadi U. Onyike, Jessica Ferrell, Danielle Brushaber, Murray Grossman, Joel H. Kramer, Eliana Marisa Ramos, Behnaz Ghazanfari, Scott M. McGinnis, Rodney Pearlman, Ralitza H. Gavrilova, Miranda Maldonado, Dana Haley, Jill Goldman, Reilly Dever, Nupur Ghoshal, Diana R. Kerwin, Lynne Jones, Kelley Faber, Joanne Taylor, Giovanni Coppola, Debra Gearhart, Ian R. A. Mackenzie, Alexander Pantelyat, Daniel I. Kaufer, Katherine P. Rankin, Rosa Rademakers, Bradley F. Boeve, Mario F. Mendez, Hilary W. Heuer, David J. Irwin, Nadine Tatton, Jeremy Syrjanen, Toji Miyagawa, John Kornak, David S. Knopman, Namita Multani, Jaya Padmanabhan

Publikováno v: Alzheimers Dement

Introduction Behavior/Comportment/Personality (BEHAV) and Language (LANG) domains were added to the Clinical Dementia Rating (CDR®) for improving evaluation of patients with frontotemporal lobar degeneration (FTLD) (CDR® plus NACC FTLD). Methods We

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ed3ce12a506428d3b0dfd4010dbff63
https://pubmed.ncbi.nlm.nih.gov/31477517