Výsledky vyhledávání - "Ruth, Harper"

Phase 3, single‐arm, multicenter study of dabigatran etexilate for secondary prevention of venous thromboembolism in children: Rationale and design

Autor: Elizabeth Chalmers, Manuela Albisetti, Martina Brueckmann, Lisa Bomgaars, Savion Gropper, Jacqueline Halton, Igor Tartakovsky, Bushi Wang, Ruth Harper, Lesley G. Mitchell, Matteo Luciani, Fenglei Huang, Ivan Manastirski, Leonardo R. Brandão, Branislav Biss

Publikováno v: Research and Practice in Thrombosis and Haemostasis

Background Anticoagulant therapy for venous thromboembolism (VTE) in children is largely based on treatment recommendations for adults. However, differences in both physiology (ie, renal maturation and drug excretion) and developmental hemostasis mus

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2f8c28968bc418667f47592eeb501ca
http://europepmc.org/articles/PMC6046601

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Design and rationale for the DIVERSITY study: An open‐label, randomized study of dabigatran etexilate for pediatric venous thromboembolism

Autor: Igor Tartakovsky, Manuela Albisetti, Martina Brueckmann, Lesley G. Mitchell, Ivan Manastirski, Lisa Bomgaars, Savion Gropper, Matteo Luciani, Jacqueline Halton, Branislav Biss, Fenglei Huang, Bushi Wang, Elizabeth Chalmers, Leonardo R. Brandão, Ruth Harper

Publikováno v: Research and Practice in Thrombosis and Haemostasis

Essentials Current standard of care (SOC) for pediatric venous thromboembolism (VTE) has limitations.Dabigatran etexilate (DE) versus SOC will be studied in children with VTE in a phase IIb/III trial.A dosing algorithm for DE in children will be asse

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e29d7b1cf50d36de29b618ff9236419f
http://europepmc.org/articles/PMC6055566

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Phase IIa study of dabigatran etexilate in children with venous thrombosis: pharmacokinetics, safety, and tolerability

Autor: Lisa Bomgaars, Lesley G. Mitchell, Igor Tartakovsky, Matteo Luciani, Savion Gropper, Jacqueline Halton, Ruth Harper, Manuela Albisetti, Hugo Maas, Fenglei Huang, Branislav Biss, Martina Brueckmann

Publikováno v: Journal of Thrombosis and Haemostasis. 15:2147-2157

Essentials Dabigatran etexilate may provide a new treatment option for pediatric venous thromboembolism. Children aged 1 to < 12 years were given dabigatran etexilate in an open-label, single-arm study. The pharmacokinetic–pharmacodynamic relations

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a837356d055ff9a3b51fe6f5164dea68
https://doi.org/10.1111/jth.13847

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Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of Dabigatran Etexilate Oral Liquid Formulation in Infants with Venous Thromboembolism

Autor: Lesley G. Mitchell, Manuela Albisetti, Savion Gropper, Jacqueline Halton, Elizabeth Chalmers, Martina Brueckmann, Ildar Nurmeev, Anne-Caroline Picard, Igor Tartakovsky, Leonardo R. Brandão, Fenglei Huang, Hugo Maas, Ruth Harper

Publikováno v: Thrombosis and Haemostasis. 117:2168-2175

Venous thromboembolism (VTE) is more frequent in infants than in older children. Treatment guidelines in children are adapted from adult VTE data, but do not currently include direct oral anticoagulant use. Dabigatran etexilate (DE) use in the paedia

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a97ace21ef4d032a53b6060635674af5
https://doi.org/10.1160/th17-06-0429

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The sum of us. Implementing a Person Centred Care Bundle - A narrative inquiry

Autor: Ruth Harper, Kate Silburn, Louise Ward

Publikováno v: Applied Nursing Research. 55:151276

Aim This study is a narrative inquiry that aims to better understand the experience of nurses implementing a Person-Centred Care (PCC) bundle onto an acute care ward in a large hospital in Melbourne, Australia. Background The PCC includes five key fo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebeac77a0179289c2e0ed0a56f4d52e3
https://doi.org/10.1016/j.apnr.2020.151276

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Elektronická kniha

Learning Everywhere on Campus : Teaching Strategies for Student Affairs Professionals

Autor: Jane Fried, Ruth Harper

Although student affairs practitioners play a key role in student learning, few are familiar with learning theories, the design of experiential education, or pedagogical theory. This edited collection describes programs in which student affairs profe

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