Hypoxia-inducible factor HIF-1α modulates drugs resistance in colon cancer cells

Autor: Martha Leonor Pinzón-Daza, Yenith Cuellar, Alejandro Ondo, Luisa Matheus, Lilia Del Riesgo, Fabio Castillo, Ruth Garzón

Publikováno v: Revista de la Facultad de Medicina, Vol 66, Iss 4, Pp 543-550 (2018)

Introduction: Drug resistance mechanisms may be associated with decreased cell death and its induction may depend on the response to oxidative stress caused by hypoxia. The correlation between hypoxia-inducible factor HIF-1α, the number of reactive

Externí odkaz: https://doaj.org/article/eb18070339a6490eb3df5d67fb17d646

Estrategias pedagógicas como herramienta educativa: 'la tutoría y el proceso formativo de los estudiantes'

Autor: María Orfa Rojas, Ruth Garzón, Lilia del Riesgo, Martha Leonor Pinzón, Alba Lucía Salamanca, Ludy Cristina Pabón

Publikováno v: Revista Iberoamericana de Educación, Vol 50, Iss 3, Pp 1-16 (2009)

La utilización de actividades académicas extra clase se presenta como una estrategia útil para que el estudiante reconozca críticamente sus debilidades y busque autónomamente soluciones, y para que el tutor trascienda los procesos de aprendizaje

Externí odkaz: https://doaj.org/article/9bd29593c0bd427e90ab13d8bbad0e51

Hypoxia-inducible factor HIF-1α modulates drugs resistance in colon cancer cells

Autor: Lilia Del Riesgo, Alejandro Ondo, Yenith Cuellar, Luisa M. Matheus, Martha L. Pinzon-Daza, Fabio Castillo, Ruth Garzón

Publikováno v: Revista de la Facultad de Medicina, Volume: 66, Issue: 4, Pages: 543-550, Published: DEC 2018
Revista de la Facultad de Medicina, Vol 66, Iss 4, Pp 543-550 (2018)
Repositorio EdocUR-U. Rosario
Universidad del Rosario
instacron:Universidad del Rosario

Introduction: Drug resistance mechanisms may be associated with decreased cell death and its induction may depend on the response to oxidative stress caused by hypoxia. The correlation between hypoxia-inducible factor HIF-1α, the number of reactive

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27f187ffc97b101d5cd699b6e6682dfa
https://doi.org/10.15446/revfacmed.v66n4.55149

The Cross-Talk between Canonical and Non-Canonical Wnt-Dependent Pathways Regulates P-Glycoprotein Expression in Human Blood–Brain Barrier Cells

Autor: Pierre-Olivier Couraud, Dario Antonio Ghigo, Joanna Kopecka, Chiara Riganti, Iris Chiara Salaroglio, Ruth Garzón, Martha L. Pinzon-Daza

Publikováno v: Repositorio EdocUR-U. Rosario
Universidad del Rosario
instacron:Universidad del Rosario

In this work, we investigate if and how transducers of the ‘canonical’ Wnt pathway, i.e., Wnt/glycogen synthase kinase 3 (GSK3)/β-catenin, and transducers of the ‘non-canonical’ Wnt pathway, i.e., Wnt/RhoA/RhoA kinase (RhoAK), cooperate to c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab4fe52847fcea925f88cabdf0b43819
https://doi.org/10.1038/jcbfm.2014.100

The association of statins plus LDL receptor-targeted liposome-encapsulated doxorubicin increasesin vitrodrug delivery across blood-brain barrier cells

Autor: Ignacio-Andres Romero, P.O. Couraud, Chiara Riganti, Ruth Garzón, Dario Antonio Ghigo, Martha L. Pinzon-Daza, Babette B. Weksler, Amalia Bosia

Publikováno v: British Journal of Pharmacology. 167:1431-1447

BACKGROUND AND PURPOSE The passage of drugs across the blood–brain barrier (BBB) limits the efficacy of chemotherapy in brain tumours. For instance, the anticancer drug doxorubicin, which is effective against glioblastoma in vitro, has poor efficac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3c769e6f9e085f88d94c1d3789482138
https://doi.org/10.1111/j.1476-5381.2012.02103.x